Incidental Mutation 'IGL01696:Olfr893'
ID104291
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Olfr893
Ensembl Gene ENSMUSG00000093901
Gene Nameolfactory receptor 893
SynonymsGA_x6K02T2PVTD-31889215-31890153, MOR170-11
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.084) question?
Stock #IGL01696
Quality Score
Status
Chromosome9
Chromosomal Location38208365-38211598 bp(+) (GRCm38)
Type of Mutationunclassified
DNA Base Change (assembly) A to C at 38209049 bp
ZygosityHeterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s): [ENSMUST00000093867] [ENSMUST00000211975]
Predicted Effect probably benign
Transcript: ENSMUST00000093867
SMART Domains Protein: ENSMUSP00000091390
Gene: ENSMUSG00000093901

DomainStartEndE-ValueType
Pfam:7tm_4 33 309 1.2e-45 PFAM
Pfam:7tm_1 43 292 8e-20 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000211975
Predicted Effect probably benign
Transcript: ENSMUST00000212815
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Allele List at MGI
Other mutations in this stock
Total: 26 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adam1b A G 5: 121,500,793 S730P possibly damaging Het
Ano3 T G 2: 110,667,737 D753A probably damaging Het
Apoc4 C T 7: 19,678,184 C113Y probably damaging Het
Arhgdia A G 11: 120,580,376 probably benign Het
Ccdc129 A G 6: 55,897,695 H210R probably benign Het
Ccdc171 A G 4: 83,655,578 T459A possibly damaging Het
Ccdc190 A C 1: 169,933,824 K165T probably damaging Het
Dopey2 T C 16: 93,770,240 V1185A probably benign Het
Ednrb C T 14: 103,823,189 V223I probably benign Het
Ermp1 T C 19: 29,646,138 I151V possibly damaging Het
Gm15737 T A 6: 92,879,821 probably benign Het
Herc3 A G 6: 58,860,386 H348R possibly damaging Het
Immp2l G T 12: 41,628,807 A95S probably damaging Het
Invs A G 4: 48,425,997 Y928C probably damaging Het
Olfr365 A G 2: 37,201,511 E90G probably benign Het
Olfr829 A T 9: 18,857,056 I135L probably benign Het
Pkd1l2 G T 8: 117,056,387 S731R probably benign Het
Pkhd1l1 T C 15: 44,529,351 M1694T possibly damaging Het
Pld2 C A 11: 70,542,780 R212S probably damaging Het
Plekhg6 A G 6: 125,378,830 F4L probably benign Het
Rps6ka6 T C X: 111,407,517 Q634R probably benign Het
Slc1a3 T C 15: 8,642,338 E378G probably benign Het
Tmem184b T C 15: 79,378,529 T43A possibly damaging Het
Ttn A G 2: 76,746,788 V24587A probably damaging Het
Uba7 T A 9: 107,977,348 L262Q probably damaging Het
Zfp954 G T 7: 7,115,398 H382Q probably damaging Het
Other mutations in Olfr893
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00331:Olfr893 APN 9 38209238 missense probably damaging 1.00
IGL00914:Olfr893 APN 9 38209799 intron probably null
IGL01563:Olfr893 APN 9 38209701 missense probably damaging 1.00
IGL02064:Olfr893 APN 9 38209578 missense probably damaging 1.00
IGL02605:Olfr893 APN 9 38209236 missense probably damaging 0.99
R0415:Olfr893 UTSW 9 38209973 missense probably benign
R0463:Olfr893 UTSW 9 38209064 missense probably benign 0.00
R0843:Olfr893 UTSW 9 38209283 missense possibly damaging 0.81
R1441:Olfr893 UTSW 9 38209481 missense probably damaging 1.00
R1939:Olfr893 UTSW 9 38209429 nonsense probably null
R2512:Olfr893 UTSW 9 38209374 missense probably damaging 1.00
R4890:Olfr893 UTSW 9 38209290 missense probably benign 0.00
R5439:Olfr893 UTSW 9 38209754 missense probably benign 0.00
R6918:Olfr893 UTSW 9 38209652 missense possibly damaging 0.95
Posted On2014-01-21