Incidental Mutation 'IGL01697:Oog2'
| ID |
104308 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Oog2
|
| Ensembl Gene |
ENSMUSG00000066030 |
| Gene Name |
oogenesin 2 |
| Synonyms |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
IGL01697
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
4 |
| Chromosomal Location |
144190719-144196934 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 144195184 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 221
(N221K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000079267
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000080405]
[ENSMUST00000143978]
|
| AlphaFold |
Q7TPX8 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000080405
AA Change: N221K
PolyPhen 2
Score 0.896 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000079267
Gene: ENSMUSG00000066030
AA Change: N221K
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1a4ya_
|
204 |
391 |
2e-7 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000129781
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000141847
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000143978
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 30 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9430015G10Rik |
T |
A |
4: 156,119,156 (GRCm38) |
|
probably benign |
Het |
| Arid2 |
A |
C |
15: 96,361,572 (GRCm38) |
|
probably null |
Het |
| Cadm1 |
C |
A |
9: 47,850,324 (GRCm38) |
D435E |
probably damaging |
Het |
| Dagla |
A |
G |
19: 10,271,198 (GRCm38) |
F33L |
probably benign |
Het |
| Edrf1 |
A |
G |
7: 133,643,730 (GRCm38) |
H199R |
probably benign |
Het |
| F5 |
T |
A |
1: 164,194,052 (GRCm38) |
N1365K |
probably benign |
Het |
| Gipc2 |
T |
G |
3: 152,137,608 (GRCm38) |
I131L |
probably benign |
Het |
| Gpc1 |
C |
T |
1: 92,858,410 (GRCm38) |
S507F |
possibly damaging |
Het |
| Grid1 |
A |
G |
14: 35,309,257 (GRCm38) |
D269G |
probably benign |
Het |
| Ighv12-3 |
A |
T |
12: 114,366,953 (GRCm38) |
M1K |
probably null |
Het |
| Kif5b |
T |
C |
18: 6,226,871 (GRCm38) |
H129R |
possibly damaging |
Het |
| Lipo3 |
A |
T |
19: 33,559,565 (GRCm38) |
C252S |
probably damaging |
Het |
| Mast4 |
A |
C |
13: 102,767,893 (GRCm38) |
N645K |
probably damaging |
Het |
| Megf9 |
T |
A |
4: 70,433,472 (GRCm38) |
T471S |
possibly damaging |
Het |
| Mmrn1 |
A |
G |
6: 60,976,493 (GRCm38) |
D586G |
possibly damaging |
Het |
| Ninl |
A |
T |
2: 150,939,947 (GRCm38) |
L1206Q |
probably damaging |
Het |
| Or13a17 |
T |
C |
7: 140,691,652 (GRCm38) |
V249A |
possibly damaging |
Het |
| Or5b96 |
T |
A |
19: 12,890,467 (GRCm38) |
T37S |
probably benign |
Het |
| Or6c8b |
C |
A |
10: 129,046,502 (GRCm38) |
C187F |
probably damaging |
Het |
| Pik3ap1 |
G |
A |
19: 41,324,579 (GRCm38) |
A365V |
probably damaging |
Het |
| Ppwd1 |
T |
C |
13: 104,220,464 (GRCm38) |
E181G |
probably benign |
Het |
| Scaf11 |
A |
C |
15: 96,423,623 (GRCm38) |
|
probably benign |
Het |
| Skic3 |
C |
T |
13: 76,128,733 (GRCm38) |
L479F |
probably benign |
Het |
| Skint7 |
T |
A |
4: 111,980,457 (GRCm38) |
|
probably benign |
Het |
| Sox14 |
T |
C |
9: 99,875,663 (GRCm38) |
I8V |
probably benign |
Het |
| Spata31f3 |
T |
A |
4: 42,874,163 (GRCm38) |
M2L |
probably benign |
Het |
| Stim1 |
A |
T |
7: 102,425,969 (GRCm38) |
|
probably benign |
Het |
| Ttll3 |
T |
C |
6: 113,399,729 (GRCm38) |
S357P |
probably benign |
Het |
| Vmn1r178 |
T |
A |
7: 23,893,689 (GRCm38) |
I54N |
probably damaging |
Het |
| Zdhhc2 |
T |
C |
8: 40,467,419 (GRCm38) |
|
probably benign |
Het |
|
| Other mutations in Oog2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00843:Oog2
|
APN |
4 |
144,195,172 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01317:Oog2
|
APN |
4 |
144,195,267 (GRCm38) |
missense |
probably benign |
0.16 |
|
IGL02237:Oog2
|
APN |
4 |
144,196,446 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
IGL02411:Oog2
|
APN |
4 |
144,195,048 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02476:Oog2
|
APN |
4 |
144,195,229 (GRCm38) |
missense |
probably benign |
0.02 |
|
IGL03284:Oog2
|
APN |
4 |
144,196,607 (GRCm38) |
unclassified |
probably benign |
|
|
IGL03394:Oog2
|
APN |
4 |
144,194,006 (GRCm38) |
missense |
probably benign |
0.17 |
|
R0538:Oog2
|
UTSW |
4 |
144,196,084 (GRCm38) |
nonsense |
probably null |
|
|
R0892:Oog2
|
UTSW |
4 |
144,196,499 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1024:Oog2
|
UTSW |
4 |
144,196,286 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4156:Oog2
|
UTSW |
4 |
144,193,953 (GRCm38) |
intron |
probably benign |
|
|
R4157:Oog2
|
UTSW |
4 |
144,193,953 (GRCm38) |
intron |
probably benign |
|
|
R4166:Oog2
|
UTSW |
4 |
144,194,841 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4167:Oog2
|
UTSW |
4 |
144,196,212 (GRCm38) |
missense |
probably benign |
0.18 |
|
R4732:Oog2
|
UTSW |
4 |
144,193,941 (GRCm38) |
intron |
probably benign |
|
|
R4734:Oog2
|
UTSW |
4 |
144,196,451 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4741:Oog2
|
UTSW |
4 |
144,195,145 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R4909:Oog2
|
UTSW |
4 |
144,195,099 (GRCm38) |
missense |
possibly damaging |
0.78 |
|
R4954:Oog2
|
UTSW |
4 |
144,190,732 (GRCm38) |
start gained |
probably benign |
|
|
R6437:Oog2
|
UTSW |
4 |
144,195,108 (GRCm38) |
splice site |
probably null |
|
|
R6487:Oog2
|
UTSW |
4 |
144,196,485 (GRCm38) |
missense |
possibly damaging |
0.48 |
|
R6946:Oog2
|
UTSW |
4 |
144,196,464 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R7000:Oog2
|
UTSW |
4 |
144,195,327 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7167:Oog2
|
UTSW |
4 |
144,195,175 (GRCm38) |
missense |
probably benign |
0.04 |
|
R7303:Oog2
|
UTSW |
4 |
144,195,342 (GRCm38) |
missense |
probably benign |
0.04 |
|
R7399:Oog2
|
UTSW |
4 |
144,195,281 (GRCm38) |
missense |
probably benign |
0.01 |
|
R8004:Oog2
|
UTSW |
4 |
144,194,251 (GRCm38) |
missense |
probably benign |
0.00 |
|
R8141:Oog2
|
UTSW |
4 |
144,194,207 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R8411:Oog2
|
UTSW |
4 |
144,194,173 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8932:Oog2
|
UTSW |
4 |
144,194,115 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9290:Oog2
|
UTSW |
4 |
144,196,445 (GRCm38) |
missense |
probably benign |
0.02 |
|
R9348:Oog2
|
UTSW |
4 |
144,195,219 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9614:Oog2
|
UTSW |
4 |
144,196,137 (GRCm38) |
missense |
probably damaging |
1.00 |
|
RF009:Oog2
|
UTSW |
4 |
144,195,285 (GRCm38) |
missense |
probably benign |
0.36 |
|
Z1177:Oog2
|
UTSW |
4 |
144,194,015 (GRCm38) |
missense |
probably damaging |
0.99 |
|
| Posted On |
2014-01-21 |
Incidental Mutation