Incidental Mutation 'IGL01697:9430015G10Rik'
ID104319
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol 9430015G10Rik
Ensembl Gene ENSMUSG00000059939
Gene NameRIKEN cDNA 9430015G10 gene
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.058) question?
Stock #IGL01697
Quality Score
Status
Chromosome4
Chromosomal Location156109982-156127265 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to A at 156119156 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000131817 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000072554] [ENSMUST00000105576] [ENSMUST00000169550]
Predicted Effect probably benign
Transcript: ENSMUST00000072554
SMART Domains Protein: ENSMUSP00000072366
Gene: ENSMUSG00000059939

DomainStartEndE-ValueType
signal peptide 1 18 N/A INTRINSIC
Pfam:DUF4501 23 199 1.5e-94 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000105576
SMART Domains Protein: ENSMUSP00000101201
Gene: ENSMUSG00000059939

DomainStartEndE-ValueType
signal peptide 1 18 N/A INTRINSIC
Pfam:DUF4501 20 51 4e-12 PFAM
Pfam:DUF4501 49 167 7.7e-69 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000125786
Predicted Effect noncoding transcript
Transcript: ENSMUST00000127332
Predicted Effect noncoding transcript
Transcript: ENSMUST00000141802
Predicted Effect noncoding transcript
Transcript: ENSMUST00000141882
Predicted Effect noncoding transcript
Transcript: ENSMUST00000154944
Predicted Effect probably benign
Transcript: ENSMUST00000169550
SMART Domains Protein: ENSMUSP00000131817
Gene: ENSMUSG00000059939

DomainStartEndE-ValueType
signal peptide 1 18 N/A INTRINSIC
Pfam:DUF4501 20 199 1e-109 PFAM
Coding Region Coverage
Validation Efficiency
MGI Phenotype PHENOTYPE: Homozygous mutant null mice show a decreased mean percentage of CD4 cells and an increased mean percentage of B cells in peripheral blood. Female mutant mice also exhibit abnormal thermal nociception, showing decreased sensitivity to acute pain during hot plate testing. [provided by MGI curators]
Allele List at MGI
Other mutations in this stock
Total: 30 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Arid2 A C 15: 96,361,572 probably null Het
Cadm1 C A 9: 47,850,324 D435E probably damaging Het
Dagla A G 19: 10,271,198 F33L probably benign Het
Edrf1 A G 7: 133,643,730 H199R probably benign Het
F5 T A 1: 164,194,052 N1365K probably benign Het
Fam205c T A 4: 42,874,163 M2L probably benign Het
Gipc2 T G 3: 152,137,608 I131L probably benign Het
Gpc1 C T 1: 92,858,410 S507F possibly damaging Het
Grid1 A G 14: 35,309,257 D269G probably benign Het
Ighv12-3 A T 12: 114,366,953 M1K probably null Het
Kif5b T C 18: 6,226,871 H129R possibly damaging Het
Lipo3 A T 19: 33,559,565 C252S probably damaging Het
Mast4 A C 13: 102,767,893 N645K probably damaging Het
Megf9 T A 4: 70,433,472 T471S possibly damaging Het
Mmrn1 A G 6: 60,976,493 D586G possibly damaging Het
Ninl A T 2: 150,939,947 L1206Q probably damaging Het
Olfr1446 T A 19: 12,890,467 T37S probably benign Het
Olfr45 T C 7: 140,691,652 V249A possibly damaging Het
Olfr765 C A 10: 129,046,502 C187F probably damaging Het
Oog2 T A 4: 144,195,184 N221K possibly damaging Het
Pik3ap1 G A 19: 41,324,579 A365V probably damaging Het
Ppwd1 T C 13: 104,220,464 E181G probably benign Het
Scaf11 A C 15: 96,423,623 probably benign Het
Skint7 T A 4: 111,980,457 probably benign Het
Sox14 T C 9: 99,875,663 I8V probably benign Het
Stim1 A T 7: 102,425,969 probably benign Het
Ttc37 C T 13: 76,128,733 L479F probably benign Het
Ttll3 T C 6: 113,399,729 S357P probably benign Het
Vmn1r178 T A 7: 23,893,689 I54N probably damaging Het
Zdhhc2 T C 8: 40,467,419 probably benign Het
Other mutations in 9430015G10Rik
AlleleSourceChrCoordTypePredicted EffectPPH Score
R1162:9430015G10Rik UTSW 4 156122418 critical splice donor site probably null
R3824:9430015G10Rik UTSW 4 156119150 splice site probably null
R5664:9430015G10Rik UTSW 4 156123559 missense probably damaging 1.00
R7711:9430015G10Rik UTSW 4 156119192 missense probably damaging 0.96
R8388:9430015G10Rik UTSW 4 156125431 missense probably damaging 1.00
Z1176:9430015G10Rik UTSW 4 156122011 missense probably benign 0.09
Z1177:9430015G10Rik UTSW 4 156122377 missense probably benign 0.38
Posted On2014-01-21