Incidental Mutation 'IGL01697:Zdhhc2'
ID104320
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Zdhhc2
Ensembl Gene ENSMUSG00000039470
Gene Namezinc finger, DHHC domain containing 2
Synonyms
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL01697
Quality Score
Status
Chromosome8
Chromosomal Location40423815-40510268 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to C at 40467419 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000129996 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000049389] [ENSMUST00000128166] [ENSMUST00000167766]
Predicted Effect probably benign
Transcript: ENSMUST00000049389
SMART Domains Protein: ENSMUSP00000041727
Gene: ENSMUSG00000039470

DomainStartEndE-ValueType
transmembrane domain 16 38 N/A INTRINSIC
Pfam:zf-DHHC 66 248 4.1e-43 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000128166
SMART Domains Protein: ENSMUSP00000123070
Gene: ENSMUSG00000039470

DomainStartEndE-ValueType
transmembrane domain 16 38 N/A INTRINSIC
transmembrane domain 48 70 N/A INTRINSIC
Pfam:zf-DHHC 122 248 1.8e-37 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000131672
Predicted Effect probably benign
Transcript: ENSMUST00000167766
SMART Domains Protein: ENSMUSP00000129996
Gene: ENSMUSG00000039470

DomainStartEndE-ValueType
transmembrane domain 16 38 N/A INTRINSIC
Pfam:zf-DHHC 66 248 4.1e-43 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 30 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
9430015G10Rik T A 4: 156,119,156 probably benign Het
Arid2 A C 15: 96,361,572 probably null Het
Cadm1 C A 9: 47,850,324 D435E probably damaging Het
Dagla A G 19: 10,271,198 F33L probably benign Het
Edrf1 A G 7: 133,643,730 H199R probably benign Het
F5 T A 1: 164,194,052 N1365K probably benign Het
Fam205c T A 4: 42,874,163 M2L probably benign Het
Gipc2 T G 3: 152,137,608 I131L probably benign Het
Gpc1 C T 1: 92,858,410 S507F possibly damaging Het
Grid1 A G 14: 35,309,257 D269G probably benign Het
Ighv12-3 A T 12: 114,366,953 M1K probably null Het
Kif5b T C 18: 6,226,871 H129R possibly damaging Het
Lipo3 A T 19: 33,559,565 C252S probably damaging Het
Mast4 A C 13: 102,767,893 N645K probably damaging Het
Megf9 T A 4: 70,433,472 T471S possibly damaging Het
Mmrn1 A G 6: 60,976,493 D586G possibly damaging Het
Ninl A T 2: 150,939,947 L1206Q probably damaging Het
Olfr1446 T A 19: 12,890,467 T37S probably benign Het
Olfr45 T C 7: 140,691,652 V249A possibly damaging Het
Olfr765 C A 10: 129,046,502 C187F probably damaging Het
Oog2 T A 4: 144,195,184 N221K possibly damaging Het
Pik3ap1 G A 19: 41,324,579 A365V probably damaging Het
Ppwd1 T C 13: 104,220,464 E181G probably benign Het
Scaf11 A C 15: 96,423,623 probably benign Het
Skint7 T A 4: 111,980,457 probably benign Het
Sox14 T C 9: 99,875,663 I8V probably benign Het
Stim1 A T 7: 102,425,969 probably benign Het
Ttc37 C T 13: 76,128,733 L479F probably benign Het
Ttll3 T C 6: 113,399,729 S357P probably benign Het
Vmn1r178 T A 7: 23,893,689 I54N probably damaging Het
Other mutations in Zdhhc2
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01751:Zdhhc2 APN 8 40473001 missense probably benign
IGL01752:Zdhhc2 APN 8 40473001 missense probably benign
IGL01800:Zdhhc2 APN 8 40464243 missense probably damaging 1.00
IGL02475:Zdhhc2 APN 8 40473025 missense probably null 1.00
IGL02554:Zdhhc2 APN 8 40462114 missense probably damaging 1.00
R0662:Zdhhc2 UTSW 8 40447098 missense probably damaging 1.00
R0720:Zdhhc2 UTSW 8 40472907 splice site probably null
R1511:Zdhhc2 UTSW 8 40467972 missense probably benign 0.00
R4738:Zdhhc2 UTSW 8 40464142 intron probably null
R5114:Zdhhc2 UTSW 8 40445784 missense probably benign 0.06
R5935:Zdhhc2 UTSW 8 40464236 missense probably damaging 0.96
R6029:Zdhhc2 UTSW 8 40472927 missense probably null
R7210:Zdhhc2 UTSW 8 40467439 missense probably damaging 0.96
R7792:Zdhhc2 UTSW 8 40447141 missense probably benign 0.02
Posted On2014-01-21