Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL01700:Vmn1r61'

104420

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r61

Ensembl Gene

ENSMUSG00000094313

Gene Name

vomeronasal 1 receptor 61

Synonyms

Gm7186

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.064) question?

Stock #

IGL01700

Quality Score

Status

Chromosome

Chromosomal Location

5610251-5612068 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 5611203 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Arginine to Serine at position 37 (R37S)

Ref Sequence

ENSEMBL: ENSMUSP00000128012 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000164880]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000164880
AA Change: R37S

PolyPhen 2 Score 0.817 (Sensitivity: 0.84; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000128012
Gene: ENSMUSG00000094313
AA Change: R37S

Domain	Start	End	E-Value	Type
Pfam:TAS2R	1	294	5.3e-12	PFAM
Pfam:7tm_1	20	279	5e-9	PFAM
Pfam:V1R	31	299	9.5e-21	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 37 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca12	T	A	1: 71,280,390	M1778L	probably benign	Het
Aldh6a1	C	T	12: 84,439,538	C202Y	probably damaging	Het
Ankrd36	A	G	11: 5,632,198	T276A	probably benign	Het
Ankrd55	T	C	13: 112,381,168	I556T	probably benign	Het
Aqp4	A	G	18: 15,399,865	I57T	probably benign	Het
Atp1a1	T	C	3: 101,594,258	D43G	possibly damaging	Het
Cyld	G	A	8: 88,707,099	R172H	probably damaging	Het
Diexf	G	A	1: 193,118,265	P416S	probably damaging	Het
Ear2	A	T	14: 44,103,259	R125*	probably null	Het
Efcab9	T	C	11: 32,527,451	R24G	probably damaging	Het
F7	C	A	8: 13,028,685	Q39K	probably benign	Het
Galntl6	A	T	8: 57,958,460		probably benign	Het
Kcnj5	A	G	9: 32,322,629	V130A	probably damaging	Het
Magee2	A	G	X: 104,855,968	I359T	possibly damaging	Het
Myh1	T	G	11: 67,211,412	I843S	probably damaging	Het
Nfat5	T	A	8: 107,339,130	M98K	probably damaging	Het
Nrip3	T	A	7: 109,761,867	N200I	possibly damaging	Het
Olfr818	A	T	10: 129,945,941	N40K	probably damaging	Het
Phkb	A	T	8: 86,017,465	Q581L	probably benign	Het
Plxdc2	T	C	2: 16,512,115	V69A	probably benign	Het
Pou3f1	G	T	4: 124,658,857	W384L	probably damaging	Het
Prrc2a	G	A	17: 35,150,667	S1890L	possibly damaging	Het
Psmc1	C	A	12: 100,113,078	P27H	probably damaging	Het
Pvr	C	A	7: 19,909,232	A359S	probably benign	Het
Rasal1	A	T	5: 120,676,817	I711F	probably benign	Het
Ror1	C	T	4: 100,409,771	A223V	probably damaging	Het
Slc22a16	A	T	10: 40,603,908	I638L	unknown	Het
Slfn10-ps	C	T	11: 83,029,112		noncoding transcript	Het
Sptbn4	A	G	7: 27,404,268	L1176P	probably damaging	Het
Usp21	A	T	1: 171,283,402	F421I	probably damaging	Het
Vps13a	G	A	19: 16,744,857	R364*	probably null	Het
Vps29	A	G	5: 122,362,867	Y165C	probably damaging	Het
Wdfy4	T	C	14: 33,020,238		probably benign	Het
Wdr24	A	G	17: 25,825,828	D219G	probably damaging	Het
Xpo1	T	C	11: 23,276,422		probably benign	Het
Zfp831	C	A	2: 174,644,918	T462K	possibly damaging	Het
Zswim5	T	C	4: 116,986,461		probably benign	Het

Other mutations in Vmn1r61

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02859:Vmn1r61	APN	7	5611289	missense	probably benign	0.37
IGL03344:Vmn1r61	APN	7	5610494	missense	possibly damaging	0.95
R0189:Vmn1r61	UTSW	7	5610700	missense	probably benign	0.03
R0336:Vmn1r61	UTSW	7	5611067	missense	probably benign
R0616:Vmn1r61	UTSW	7	5610999	missense	possibly damaging	0.65
R1490:Vmn1r61	UTSW	7	5611243	missense	probably benign	0.00
R1737:Vmn1r61	UTSW	7	5611061	missense	probably benign	0.01
R1755:Vmn1r61	UTSW	7	5611303	nonsense	probably null
R1795:Vmn1r61	UTSW	7	5611325	utr 5 prime	probably benign
R3929:Vmn1r61	UTSW	7	5611177	missense	probably benign	0.01
R4487:Vmn1r61	UTSW	7	5610925	missense	possibly damaging	0.76
R4629:Vmn1r61	UTSW	7	5611250	missense	probably benign	0.08
R4785:Vmn1r61	UTSW	7	5611125	nonsense	probably null
R4785:Vmn1r61	UTSW	7	5611127	missense	probably benign
R5108:Vmn1r61	UTSW	7	5610520	missense	probably benign
R5305:Vmn1r61	UTSW	7	5610815	missense	probably damaging	1.00
R5914:Vmn1r61	UTSW	7	5610530	missense	probably damaging	1.00
R6150:Vmn1r61	UTSW	7	5610679	missense	probably benign	0.00
R6232:Vmn1r61	UTSW	7	5610851	missense	probably damaging	1.00
R6722:Vmn1r61	UTSW	7	5610688	missense	possibly damaging	0.55
R7488:Vmn1r61	UTSW	7	5610768	missense	possibly damaging	0.56
R7496:Vmn1r61	UTSW	7	5610431	missense	probably benign	0.19
R8353:Vmn1r61	UTSW	7	5610887	missense	probably benign	0.11
R8453:Vmn1r61	UTSW	7	5610887	missense	probably benign	0.11
R8847:Vmn1r61	UTSW	7	5610818	missense	probably damaging	1.00

Posted On

2014-01-21