Incidental Mutation 'IGL01700:Vmn1r61'
| ID |
104420 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r61
|
| Ensembl Gene |
ENSMUSG00000094313 |
| Gene Name |
vomeronasal 1 receptor 61 |
| Synonyms |
Gm7186 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.069)
|
| Stock # |
IGL01700
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
5613410-5614312 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 5614202 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Serine
at position 37
(R37S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000128012
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000164880]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000164880
AA Change: R37S
PolyPhen 2
Score 0.817 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000128012
Gene: ENSMUSG00000094313
AA Change: R37S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
1 |
294 |
5.3e-12 |
PFAM |
|
Pfam:7tm_1
|
20 |
279 |
5e-9 |
PFAM |
|
Pfam:V1R
|
31 |
299 |
9.5e-21 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 37 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca12 |
T |
A |
1: 71,319,549 (GRCm39) |
M1778L |
probably benign |
Het |
| Aldh6a1 |
C |
T |
12: 84,486,312 (GRCm39) |
C202Y |
probably damaging |
Het |
| Ankrd36 |
A |
G |
11: 5,582,198 (GRCm39) |
T276A |
probably benign |
Het |
| Ankrd55 |
T |
C |
13: 112,517,702 (GRCm39) |
I556T |
probably benign |
Het |
| Aqp4 |
A |
G |
18: 15,532,922 (GRCm39) |
I57T |
probably benign |
Het |
| Atp1a1 |
T |
C |
3: 101,501,574 (GRCm39) |
D43G |
possibly damaging |
Het |
| Cyld |
G |
A |
8: 89,433,727 (GRCm39) |
R172H |
probably damaging |
Het |
| Ear2 |
A |
T |
14: 44,340,716 (GRCm39) |
R125* |
probably null |
Het |
| Efcab9 |
T |
C |
11: 32,477,451 (GRCm39) |
R24G |
probably damaging |
Het |
| F7 |
C |
A |
8: 13,078,685 (GRCm39) |
Q39K |
probably benign |
Het |
| Galntl6 |
A |
T |
8: 58,411,494 (GRCm39) |
|
probably benign |
Het |
| Kcnj5 |
A |
G |
9: 32,233,925 (GRCm39) |
V130A |
probably damaging |
Het |
| Magee2 |
A |
G |
X: 103,899,574 (GRCm39) |
I359T |
possibly damaging |
Het |
| Myh1 |
T |
G |
11: 67,102,238 (GRCm39) |
I843S |
probably damaging |
Het |
| Nfat5 |
T |
A |
8: 108,065,762 (GRCm39) |
M98K |
probably damaging |
Het |
| Nrip3 |
T |
A |
7: 109,361,074 (GRCm39) |
N200I |
possibly damaging |
Het |
| Or6c219 |
A |
T |
10: 129,781,810 (GRCm39) |
N40K |
probably damaging |
Het |
| Phkb |
A |
T |
8: 86,744,094 (GRCm39) |
Q581L |
probably benign |
Het |
| Plxdc2 |
T |
C |
2: 16,516,926 (GRCm39) |
V69A |
probably benign |
Het |
| Pou3f1 |
G |
T |
4: 124,552,650 (GRCm39) |
W384L |
probably damaging |
Het |
| Prrc2a |
G |
A |
17: 35,369,643 (GRCm39) |
S1890L |
possibly damaging |
Het |
| Psmc1 |
C |
A |
12: 100,079,337 (GRCm39) |
P27H |
probably damaging |
Het |
| Pvr |
C |
A |
7: 19,643,157 (GRCm39) |
A359S |
probably benign |
Het |
| Rasal1 |
A |
T |
5: 120,814,882 (GRCm39) |
I711F |
probably benign |
Het |
| Ror1 |
C |
T |
4: 100,266,968 (GRCm39) |
A223V |
probably damaging |
Het |
| Slc22a16 |
A |
T |
10: 40,479,904 (GRCm39) |
I638L |
unknown |
Het |
| Slfn10-ps |
C |
T |
11: 82,919,938 (GRCm39) |
|
noncoding transcript |
Het |
| Sptbn4 |
A |
G |
7: 27,103,693 (GRCm39) |
L1176P |
probably damaging |
Het |
| Usp21 |
A |
T |
1: 171,110,975 (GRCm39) |
F421I |
probably damaging |
Het |
| Utp25 |
G |
A |
1: 192,800,573 (GRCm39) |
P416S |
probably damaging |
Het |
| Vps13a |
G |
A |
19: 16,722,221 (GRCm39) |
R364* |
probably null |
Het |
| Vps29 |
A |
G |
5: 122,500,930 (GRCm39) |
Y165C |
probably damaging |
Het |
| Wdfy4 |
T |
C |
14: 32,742,195 (GRCm39) |
|
probably benign |
Het |
| Wdr24 |
A |
G |
17: 26,044,802 (GRCm39) |
D219G |
probably damaging |
Het |
| Xpo1 |
T |
C |
11: 23,226,422 (GRCm39) |
|
probably benign |
Het |
| Zfp831 |
C |
A |
2: 174,486,711 (GRCm39) |
T462K |
possibly damaging |
Het |
| Zswim5 |
T |
C |
4: 116,843,658 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Vmn1r61 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02859:Vmn1r61
|
APN |
7 |
5,614,288 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL03344:Vmn1r61
|
APN |
7 |
5,613,493 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0189:Vmn1r61
|
UTSW |
7 |
5,613,699 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0336:Vmn1r61
|
UTSW |
7 |
5,614,066 (GRCm39) |
missense |
probably benign |
|
|
R0616:Vmn1r61
|
UTSW |
7 |
5,613,998 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R1490:Vmn1r61
|
UTSW |
7 |
5,614,242 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1737:Vmn1r61
|
UTSW |
7 |
5,614,060 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1755:Vmn1r61
|
UTSW |
7 |
5,614,302 (GRCm39) |
nonsense |
probably null |
|
|
R1795:Vmn1r61
|
UTSW |
7 |
5,614,324 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R3929:Vmn1r61
|
UTSW |
7 |
5,614,176 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4487:Vmn1r61
|
UTSW |
7 |
5,613,924 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R4629:Vmn1r61
|
UTSW |
7 |
5,614,249 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4785:Vmn1r61
|
UTSW |
7 |
5,614,126 (GRCm39) |
missense |
probably benign |
|
|
R4785:Vmn1r61
|
UTSW |
7 |
5,614,124 (GRCm39) |
nonsense |
probably null |
|
|
R5108:Vmn1r61
|
UTSW |
7 |
5,613,519 (GRCm39) |
missense |
probably benign |
|
|
R5305:Vmn1r61
|
UTSW |
7 |
5,613,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5914:Vmn1r61
|
UTSW |
7 |
5,613,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6150:Vmn1r61
|
UTSW |
7 |
5,613,678 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6232:Vmn1r61
|
UTSW |
7 |
5,613,850 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6722:Vmn1r61
|
UTSW |
7 |
5,613,687 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R7488:Vmn1r61
|
UTSW |
7 |
5,613,767 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R7496:Vmn1r61
|
UTSW |
7 |
5,613,430 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8353:Vmn1r61
|
UTSW |
7 |
5,613,886 (GRCm39) |
missense |
probably benign |
0.11 |
|
R8453:Vmn1r61
|
UTSW |
7 |
5,613,886 (GRCm39) |
missense |
probably benign |
0.11 |
|
R8847:Vmn1r61
|
UTSW |
7 |
5,613,817 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9549:Vmn1r61
|
UTSW |
7 |
5,614,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9559:Vmn1r61
|
UTSW |
7 |
5,613,498 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Posted On |
2014-01-21 |
Incidental Mutation