Incidental Mutation 'IGL01712:Tex16'
ID104831
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Tex16
Ensembl Gene ENSMUSG00000034555
Gene Nametestis expressed gene 16
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.072) question?
Stock #IGL01712
Quality Score
Status
ChromosomeX
Chromosomal Location112011007-112127326 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 112093754 bp
ZygosityHeterozygous
Amino Acid Change Serine to Proline at position 87 (S87P)
Ref Sequence ENSEMBL: ENSMUSP00000118847 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000038546] [ENSMUST00000130247] [ENSMUST00000207962]
Predicted Effect probably damaging
Transcript: ENSMUST00000038546
AA Change: S76P

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000048187
Gene: ENSMUSG00000034555
AA Change: S76P

DomainStartEndE-ValueType
low complexity region 1 12 N/A INTRINSIC
low complexity region 110 122 N/A INTRINSIC
low complexity region 616 669 N/A INTRINSIC
low complexity region 674 699 N/A INTRINSIC
low complexity region 811 824 N/A INTRINSIC
low complexity region 833 850 N/A INTRINSIC
Predicted Effect probably damaging
Transcript: ENSMUST00000130247
AA Change: S87P

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000118847
Gene: ENSMUSG00000034555
AA Change: S87P

DomainStartEndE-ValueType
low complexity region 10 24 N/A INTRINSIC
low complexity region 121 133 N/A INTRINSIC
low complexity region 627 680 N/A INTRINSIC
low complexity region 685 710 N/A INTRINSIC
low complexity region 822 835 N/A INTRINSIC
low complexity region 844 861 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000131304
Predicted Effect probably benign
Transcript: ENSMUST00000207962
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 48 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adgrb3 A G 1: 25,826,279 V161A probably benign Het
Arhgdib G A 6: 136,924,197 T178M probably damaging Het
Atp11a T A 8: 12,851,138 I989K probably benign Het
Bcam T C 7: 19,758,767 S498G probably damaging Het
Bcas3 A G 11: 85,581,048 I728V probably damaging Het
Cep57 G T 9: 13,813,417 P119Q possibly damaging Het
Clip4 T A 17: 71,799,041 I73N probably damaging Het
Cpa4 A G 6: 30,590,816 D371G possibly damaging Het
Dnah7a A G 1: 53,423,270 S3721P probably benign Het
Fam166a T C 2: 25,218,792 probably benign Het
Fcrla T C 1: 170,921,623 probably null Het
Foxg1 T C 12: 49,385,620 S379P possibly damaging Het
Gatm T A 2: 122,600,825 Y227F possibly damaging Het
Gm8298 T A 3: 59,868,900 I164N possibly damaging Het
Grid2 A T 6: 64,665,915 D887V possibly damaging Het
Gtpbp6 A T 5: 110,104,379 I429N probably benign Het
Ighmbp2 A G 19: 3,273,038 probably benign Het
Irs4 T C X: 141,722,399 N934D unknown Het
Kif16b T A 2: 142,648,471 N1257I probably damaging Het
L1cam T C X: 73,864,438 Y169C probably damaging Het
L3mbtl3 A T 10: 26,276,235 M821K probably damaging Het
Lig3 A G 11: 82,789,541 probably benign Het
Lpin2 T A 17: 71,215,068 D32E probably damaging Het
Mcoln3 T C 3: 146,128,264 probably benign Het
Mgst2 T C 3: 51,664,571 V40A probably damaging Het
Mov10l1 T C 15: 89,024,766 S997P probably damaging Het
Mycbpap G T 11: 94,512,655 H187Q possibly damaging Het
Olfr136 A T 17: 38,335,957 T267S probably benign Het
Olfr652 T C 7: 104,565,019 V266A probably benign Het
Onecut2 T A 18: 64,386,602 S478T probably damaging Het
Pcdhb5 A T 18: 37,321,253 I229F probably damaging Het
Pfas A G 11: 68,991,060 V933A probably benign Het
Phldb2 A T 16: 45,751,429 I1200N probably damaging Het
Pla2g4e C A 2: 120,189,403 probably null Het
Prr36 G A 8: 4,215,243 P169L probably damaging Het
Rhot2 A G 17: 25,841,360 probably null Het
Serpina3f C T 12: 104,218,398 P267L probably damaging Het
Sppl2a C T 2: 126,904,903 probably benign Het
Tas2r122 A T 6: 132,711,762 M56K possibly damaging Het
Tbxas1 A G 6: 39,081,060 T450A probably benign Het
Them7 T A 2: 105,378,885 F183L possibly damaging Het
Tmbim7 A G 5: 3,670,074 T116A probably damaging Het
Tomm40 G T 7: 19,703,363 S224R probably benign Het
Top3a A T 11: 60,761,736 I84N probably damaging Het
Vmn1r28 A G 6: 58,265,408 T79A probably benign Het
Vmn2r61 A T 7: 42,260,237 Y62F probably damaging Het
Zbtb42 T C 12: 112,680,284 C298R probably benign Het
Zfp395 G A 14: 65,386,387 E102K probably damaging Het
Other mutations in Tex16
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02576:Tex16 APN X 112118956 missense probably benign 0.07
IGL03261:Tex16 APN X 112118855 missense possibly damaging 0.90
R2274:Tex16 UTSW X 112121141 missense probably damaging 0.98
R3607:Tex16 UTSW X 112093970 missense probably damaging 1.00
R4209:Tex16 UTSW X 112120943 missense probably benign 0.01
R4210:Tex16 UTSW X 112120943 missense probably benign 0.01
U24488:Tex16 UTSW X 112119118 missense probably benign 0.05
Posted On2014-01-21