Incidental Mutation 'IGL01718:Mrgpra1'
ID105016
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Mrgpra1
Ensembl Gene ENSMUSG00000050650
Gene NameMAS-related GPR, member A1
SynonymsMrgA1
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.054) question?
Stock #IGL01718
Quality Score
Status
Chromosome7
Chromosomal Location47334875-47354240 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to T at 47335927 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000129978 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000098438]
Predicted Effect probably null
Transcript: ENSMUST00000098438
SMART Domains Protein: ENSMUSP00000129978
Gene: ENSMUSG00000050650

DomainStartEndE-ValueType
low complexity region 14 27 N/A INTRINSIC
low complexity region 36 49 N/A INTRINSIC
Pfam:7tm_1 57 225 2.1e-8 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 28 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Aldh1a3 A G 7: 66,400,205 F422L possibly damaging Het
Ap2m1 T C 16: 20,542,194 probably benign Het
Asic1 A G 15: 99,672,002 Y68C probably damaging Het
Ccdc18 A G 5: 108,201,348 D1002G possibly damaging Het
Cyp2c29 A T 19: 39,330,260 I434F possibly damaging Het
Diaph3 T A 14: 86,656,338 R78S unknown Het
Dnase1l2 T C 17: 24,441,716 D188G possibly damaging Het
Exosc9 T C 3: 36,553,929 probably benign Het
Fgf23 G A 6: 127,080,473 V251I probably benign Het
Fndc3c1 T C X: 106,445,928 T296A probably benign Het
Gm5592 A G 7: 41,289,193 E633G probably damaging Het
Gm7102 A G 19: 61,175,761 S79P probably damaging Het
Gpr155 T C 2: 73,382,232 M16V probably benign Het
Jakmip3 T G 7: 138,989,392 S2A possibly damaging Het
Lrba T A 3: 86,351,248 N1347K probably damaging Het
Mars T C 10: 127,305,838 R266G possibly damaging Het
Olfr835 T A 9: 19,035,288 L55* probably null Het
Pdzk1ip1 T A 4: 115,092,914 probably benign Het
Ppid G T 3: 79,593,679 C52F probably damaging Het
Reln A G 5: 21,947,514 I2318T possibly damaging Het
Rhpn2 G A 7: 35,370,754 D146N probably benign Het
Tspoap1 G T 11: 87,780,255 R1670L possibly damaging Het
Ttc22 G A 4: 106,638,576 V376M probably damaging Het
Ttn T A 2: 76,730,402 L29218F probably damaging Het
Ttn A T 2: 76,730,404 L29218I probably damaging Het
Zfp609 G A 9: 65,702,400 Q1094* probably null Het
Zfp831 C T 2: 174,643,838 T102I possibly damaging Het
Zglp1 C T 9: 21,063,379 C171Y probably benign Het
Other mutations in Mrgpra1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00903:Mrgpra1 APN 7 47335578 missense probably benign 0.00
IGL01317:Mrgpra1 APN 7 47335624 missense probably benign 0.00
IGL02252:Mrgpra1 APN 7 47335164 missense probably benign 0.00
IGL03301:Mrgpra1 APN 7 47335416 missense probably benign
R0012:Mrgpra1 UTSW 7 47335470 missense probably damaging 0.98
R1019:Mrgpra1 UTSW 7 47335085 missense probably benign 0.00
R2224:Mrgpra1 UTSW 7 47335106 missense possibly damaging 0.50
R2520:Mrgpra1 UTSW 7 47335272 missense possibly damaging 0.75
R2924:Mrgpra1 UTSW 7 47334870 splice site probably null
R3038:Mrgpra1 UTSW 7 47334996 nonsense probably null
R3900:Mrgpra1 UTSW 7 47335527 missense possibly damaging 0.76
R4692:Mrgpra1 UTSW 7 47335698 missense probably damaging 1.00
R4783:Mrgpra1 UTSW 7 47335470 missense probably damaging 0.98
R4784:Mrgpra1 UTSW 7 47335470 missense probably damaging 0.98
R4785:Mrgpra1 UTSW 7 47335470 missense probably damaging 0.98
R4981:Mrgpra1 UTSW 7 47335211 missense probably damaging 1.00
R5031:Mrgpra1 UTSW 7 47335237 nonsense probably null
R6760:Mrgpra1 UTSW 7 47335041 missense probably benign 0.03
R7305:Mrgpra1 UTSW 7 47335455 missense probably benign 0.38
R7348:Mrgpra1 UTSW 7 47335409 missense probably benign 0.09
R7837:Mrgpra1 UTSW 7 47335328 missense possibly damaging 0.68
R8158:Mrgpra1 UTSW 7 47335456 nonsense probably null
R8856:Mrgpra1 UTSW 7 47335835 missense probably benign 0.30
X0012:Mrgpra1 UTSW 7 47335875 missense probably benign
Posted On2014-01-21