Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL01727:Trcg1'

105310

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Trcg1

Ensembl Gene

ENSMUSG00000070298

Gene Name

taste receptor cell gene 1

Synonyms

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.057) question?

Stock #

IGL01727

Quality Score

Status

Chromosome

Chromosomal Location

57236556-57249864 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 57242273 bp

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Threonine at position 376 (I376T)

Ref Sequence

ENSEMBL: ENSMUSP00000091357 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000093837]

Predicted Effect

probably benign
Transcript: ENSMUST00000093837
AA Change: I376T

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000091357
Gene: ENSMUSG00000070298
AA Change: I376T

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
low complexity region	302	335	N/A	INTRINSIC
Blast:SEA	449	549	5e-21	BLAST
low complexity region	580	594	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 37 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adam19	C	T	11: 46,121,553	A292V	probably benign	Het
Ankrd26	A	G	6: 118,511,636	L1354P	probably damaging	Het
Aox1	T	A	1: 58,073,228	C720*	probably null	Het
Aqp5	T	C	15: 99,591,621	L117P	probably damaging	Het
BC005561	A	G	5: 104,519,513	T634A	probably benign	Het
Col9a3	T	C	2: 180,616,565		probably null	Het
Ctrc	T	C	4: 141,843,761	Y56C	probably damaging	Het
Dsc2	T	A	18: 20,038,200	T581S	probably benign	Het
Grap2	T	C	15: 80,634,409	I51T	probably damaging	Het
Herc2	A	G	7: 56,137,806	Y1737C	probably damaging	Het
Hook3	A	G	8: 26,070,159	M346T	probably benign	Het
Lancl1	C	T	1: 67,020,942	C108Y	probably damaging	Het
Lpin2	T	C	17: 71,246,452	C824R	probably damaging	Het
Mlip	T	C	9: 77,239,748	S88G	probably damaging	Het
Mtdh	T	G	15: 34,083,109	L25R	probably damaging	Het
Musk	A	G	4: 58,303,887	I177V	probably benign	Het
Nov	G	A	15: 54,746,238	A45T	probably benign	Het
Olfr1148	T	C	2: 87,833,500	S154P	probably damaging	Het
Olfr1186	A	G	2: 88,525,927	M115V	probably benign	Het
Olfr1504	A	G	19: 13,887,878	C111R	probably damaging	Het
Pabpc4l	C	A	3: 46,446,665	E181D	probably damaging	Het
Pcdh18	A	G	3: 49,755,700	S389P	probably damaging	Het
Ptk7	A	G	17: 46,572,548	Y864H	probably damaging	Het
Rbp4	A	G	19: 38,124,052	V155A	probably benign	Het
Rilpl1	C	T	5: 124,530,944	A14T	possibly damaging	Het
Rnf148	T	A	6: 23,655,002		probably benign	Het
Rnf219	G	A	14: 104,479,387	R517*	probably null	Het
Ska2	T	A	11: 87,116,147	L26Q	probably damaging	Het
Slc29a2	T	A	19: 5,026,458	F125I	probably damaging	Het
Smap2	A	G	4: 120,982,208		probably benign	Het
St6galnac2	C	T	11: 116,685,119	D169N	probably damaging	Het
Supt7l	A	G	5: 31,520,342	V160A	possibly damaging	Het
Susd1	A	G	4: 59,412,329		probably benign	Het
Syne1	T	C	10: 5,047,842	D375G	probably damaging	Het
Tpst2	G	A	5: 112,309,858	D351N	probably damaging	Het
Tsga10	T	C	1: 37,835,274	E148G	probably damaging	Het
Zranb1	G	T	7: 132,966,620	D336Y	probably damaging	Het

Other mutations in Trcg1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01727:Trcg1	APN	9	57242594	missense	probably damaging	0.97
IGL02147:Trcg1	APN	9	57245849	missense	probably benign	0.20
IGL02329:Trcg1	APN	9	57240393	missense	possibly damaging	0.92
IGL02658:Trcg1	APN	9	57242228	nonsense	probably null
IGL02852:Trcg1	APN	9	57241312	missense	possibly damaging	0.94
IGL03163:Trcg1	APN	9	57248347	missense	possibly damaging	0.92
FR4589:Trcg1	UTSW	9	57242202	frame shift	probably null
R0555:Trcg1	UTSW	9	57242333	missense	probably damaging	1.00
R0747:Trcg1	UTSW	9	57241921	missense	probably benign	0.00
R1061:Trcg1	UTSW	9	57245873	missense	possibly damaging	0.66
R1521:Trcg1	UTSW	9	57242465	missense	probably benign	0.36
R1622:Trcg1	UTSW	9	57248672	missense	possibly damaging	0.94
R1652:Trcg1	UTSW	9	57245573	missense	probably damaging	0.99
R4677:Trcg1	UTSW	9	57245861	missense	possibly damaging	0.94
R4879:Trcg1	UTSW	9	57246720	missense	probably damaging	0.99
R5013:Trcg1	UTSW	9	57242279	missense	probably damaging	0.99
R5141:Trcg1	UTSW	9	57241304	missense	probably damaging	1.00
R5690:Trcg1	UTSW	9	57241811	missense	probably benign	0.36
R6416:Trcg1	UTSW	9	57241330	missense	possibly damaging	0.46
R6980:Trcg1	UTSW	9	57245573	missense	probably damaging	0.99
R7022:Trcg1	UTSW	9	57241569	missense	possibly damaging	0.46
R7172:Trcg1	UTSW	9	57248335	missense	probably benign	0.01
R7276:Trcg1	UTSW	9	57242579	missense	probably damaging	0.99
R7412:Trcg1	UTSW	9	57241483	missense	probably benign	0.00
R7546:Trcg1	UTSW	9	57248338	missense	probably benign	0.34
R7942:Trcg1	UTSW	9	57242216	missense	probably benign
R8087:Trcg1	UTSW	9	57248674	missense	probably damaging	0.99
R8094:Trcg1	UTSW	9	57242281	missense	probably benign	0.01

Posted On

2014-01-21