Incidental Mutation 'IGL01727:Trcg1'
| ID |
105310 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Trcg1
|
| Ensembl Gene |
ENSMUSG00000070298 |
| Gene Name |
taste receptor cell gene 1 |
| Synonyms |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.073)
|
| Stock # |
IGL01727
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
9 |
| Chromosomal Location |
57143839-57157147 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 57149556 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Threonine
at position 376
(I376T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000091357
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000093837]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000093837
AA Change: I376T
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000091357
Gene: ENSMUSG00000070298
AA Change: I376T
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
low complexity region
|
302 |
335 |
N/A |
INTRINSIC |
|
Blast:SEA
|
449 |
549 |
5e-21 |
BLAST |
|
low complexity region
|
580 |
594 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 37 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam19 |
C |
T |
11: 46,012,380 (GRCm39) |
A292V |
probably benign |
Het |
| Ankrd26 |
A |
G |
6: 118,488,597 (GRCm39) |
L1354P |
probably damaging |
Het |
| Aox1 |
T |
A |
1: 58,112,387 (GRCm39) |
C720* |
probably null |
Het |
| Aqp5 |
T |
C |
15: 99,489,502 (GRCm39) |
L117P |
probably damaging |
Het |
| Ccn3 |
G |
A |
15: 54,609,634 (GRCm39) |
A45T |
probably benign |
Het |
| Col9a3 |
T |
C |
2: 180,258,358 (GRCm39) |
|
probably null |
Het |
| Ctrc |
T |
C |
4: 141,571,072 (GRCm39) |
Y56C |
probably damaging |
Het |
| Dsc2 |
T |
A |
18: 20,171,257 (GRCm39) |
T581S |
probably benign |
Het |
| Grap2 |
T |
C |
15: 80,518,610 (GRCm39) |
I51T |
probably damaging |
Het |
| Herc2 |
A |
G |
7: 55,787,554 (GRCm39) |
Y1737C |
probably damaging |
Het |
| Hook3 |
A |
G |
8: 26,560,187 (GRCm39) |
M346T |
probably benign |
Het |
| Lancl1 |
C |
T |
1: 67,060,101 (GRCm39) |
C108Y |
probably damaging |
Het |
| Lpin2 |
T |
C |
17: 71,553,447 (GRCm39) |
C824R |
probably damaging |
Het |
| Mlip |
T |
C |
9: 77,147,030 (GRCm39) |
S88G |
probably damaging |
Het |
| Mtdh |
T |
G |
15: 34,083,255 (GRCm39) |
L25R |
probably damaging |
Het |
| Musk |
A |
G |
4: 58,303,887 (GRCm39) |
I177V |
probably benign |
Het |
| Obi1 |
G |
A |
14: 104,716,823 (GRCm39) |
R517* |
probably null |
Het |
| Or12e13 |
T |
C |
2: 87,663,844 (GRCm39) |
S154P |
probably damaging |
Het |
| Or4c100 |
A |
G |
2: 88,356,271 (GRCm39) |
M115V |
probably benign |
Het |
| Or9i16 |
A |
G |
19: 13,865,242 (GRCm39) |
C111R |
probably damaging |
Het |
| Pabpc4l |
C |
A |
3: 46,401,100 (GRCm39) |
E181D |
probably damaging |
Het |
| Pcdh18 |
A |
G |
3: 49,710,149 (GRCm39) |
S389P |
probably damaging |
Het |
| Ptk7 |
A |
G |
17: 46,883,474 (GRCm39) |
Y864H |
probably damaging |
Het |
| Rbp4 |
A |
G |
19: 38,112,500 (GRCm39) |
V155A |
probably benign |
Het |
| Rilpl1 |
C |
T |
5: 124,669,007 (GRCm39) |
A14T |
possibly damaging |
Het |
| Rnf148 |
T |
A |
6: 23,655,001 (GRCm39) |
|
probably benign |
Het |
| Ska2 |
T |
A |
11: 87,006,973 (GRCm39) |
L26Q |
probably damaging |
Het |
| Slc29a2 |
T |
A |
19: 5,076,486 (GRCm39) |
F125I |
probably damaging |
Het |
| Smap2 |
A |
G |
4: 120,839,405 (GRCm39) |
|
probably benign |
Het |
| St6galnac2 |
C |
T |
11: 116,575,945 (GRCm39) |
D169N |
probably damaging |
Het |
| Supt7l |
A |
G |
5: 31,677,686 (GRCm39) |
V160A |
possibly damaging |
Het |
| Susd1 |
A |
G |
4: 59,412,329 (GRCm39) |
|
probably benign |
Het |
| Syne1 |
T |
C |
10: 4,997,842 (GRCm39) |
D375G |
probably damaging |
Het |
| Thoc2l |
A |
G |
5: 104,667,379 (GRCm39) |
T634A |
probably benign |
Het |
| Tpst2 |
G |
A |
5: 112,457,724 (GRCm39) |
D351N |
probably damaging |
Het |
| Tsga10 |
T |
C |
1: 37,874,355 (GRCm39) |
E148G |
probably damaging |
Het |
| Zranb1 |
G |
T |
7: 132,568,349 (GRCm39) |
D336Y |
probably damaging |
Het |
|
| Other mutations in Trcg1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01727:Trcg1
|
APN |
9 |
57,149,877 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02147:Trcg1
|
APN |
9 |
57,153,132 (GRCm39) |
missense |
probably benign |
0.20 |
|
IGL02329:Trcg1
|
APN |
9 |
57,147,676 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02658:Trcg1
|
APN |
9 |
57,149,511 (GRCm39) |
nonsense |
probably null |
|
|
IGL02852:Trcg1
|
APN |
9 |
57,148,595 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03163:Trcg1
|
APN |
9 |
57,155,630 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
FR4589:Trcg1
|
UTSW |
9 |
57,149,485 (GRCm39) |
frame shift |
probably null |
|
|
R0555:Trcg1
|
UTSW |
9 |
57,149,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0747:Trcg1
|
UTSW |
9 |
57,149,204 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1061:Trcg1
|
UTSW |
9 |
57,153,156 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1521:Trcg1
|
UTSW |
9 |
57,149,748 (GRCm39) |
missense |
probably benign |
0.36 |
|
R1622:Trcg1
|
UTSW |
9 |
57,155,955 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1652:Trcg1
|
UTSW |
9 |
57,152,856 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4677:Trcg1
|
UTSW |
9 |
57,153,144 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4879:Trcg1
|
UTSW |
9 |
57,154,003 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5013:Trcg1
|
UTSW |
9 |
57,149,562 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5141:Trcg1
|
UTSW |
9 |
57,148,587 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5690:Trcg1
|
UTSW |
9 |
57,149,094 (GRCm39) |
missense |
probably benign |
0.36 |
|
R6416:Trcg1
|
UTSW |
9 |
57,148,613 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6980:Trcg1
|
UTSW |
9 |
57,152,856 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7022:Trcg1
|
UTSW |
9 |
57,148,852 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7172:Trcg1
|
UTSW |
9 |
57,155,618 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7276:Trcg1
|
UTSW |
9 |
57,149,862 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7412:Trcg1
|
UTSW |
9 |
57,148,766 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7546:Trcg1
|
UTSW |
9 |
57,155,621 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7942:Trcg1
|
UTSW |
9 |
57,149,499 (GRCm39) |
missense |
probably benign |
|
|
R8087:Trcg1
|
UTSW |
9 |
57,155,957 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8094:Trcg1
|
UTSW |
9 |
57,149,564 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8825:Trcg1
|
UTSW |
9 |
57,148,754 (GRCm39) |
missense |
probably benign |
0.19 |
|
| Posted On |
2014-01-21 |
Incidental Mutation