Incidental Mutation 'IGL00767:Mindy2'
ID10668
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Mindy2
Ensembl Gene ENSMUSG00000042444
Gene NameMINDY lysine 48 deubiquitinase 2
SynonymsB230380D07Rik, Fam63b
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.127) question?
Stock #IGL00767
Quality Score
Status
Chromosome9
Chromosomal Location70599014-70657174 bp(-) (GRCm38)
Type of Mutationcritical splice donor site (2 bp from exon)
DNA Base Change (assembly) A to G at 70634003 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000150300 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000049031] [ENSMUST00000213380]
Predicted Effect probably null
Transcript: ENSMUST00000049031
SMART Domains Protein: ENSMUSP00000037035
Gene: ENSMUSG00000042444

DomainStartEndE-ValueType
low complexity region 22 41 N/A INTRINSIC
low complexity region 79 86 N/A INTRINSIC
low complexity region 126 173 N/A INTRINSIC
low complexity region 186 195 N/A INTRINSIC
Pfam:DUF544 250 373 6.9e-42 PFAM
low complexity region 498 508 N/A INTRINSIC
low complexity region 535 570 N/A INTRINSIC
low complexity region 578 595 N/A INTRINSIC
Predicted Effect probably null
Transcript: ENSMUST00000213380
Predicted Effect noncoding transcript
Transcript: ENSMUST00000214293
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 20 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2810474O19Rik T C 6: 149,334,750 probably benign Het
Anpep A C 7: 79,840,890 S293A probably benign Het
Dgkh T A 14: 78,587,261 probably benign Het
Dlg5 T A 14: 24,165,285 T657S probably damaging Het
Hpf1 A G 8: 60,896,802 I155V probably benign Het
Il12rb2 T C 6: 67,303,562 I554V possibly damaging Het
Nostrin A G 2: 69,175,775 T268A probably benign Het
Npy6r A G 18: 44,276,318 T269A probably benign Het
Nt5dc3 T A 10: 86,820,273 probably benign Het
Osgin2 G A 4: 16,006,377 H106Y probably damaging Het
Pdlim3 G A 8: 45,896,790 G46R probably damaging Het
Pdpk1 T G 17: 24,106,861 K147N possibly damaging Het
Pfkfb3 T C 2: 11,488,754 D137G probably damaging Het
Polg G A 7: 79,451,925 P1048S probably damaging Het
Ptcd3 A T 6: 71,903,448 I97K probably damaging Het
Serpinb10 G T 1: 107,536,077 V30F possibly damaging Het
Stk17b A G 1: 53,764,023 probably benign Het
Tll1 G A 8: 64,071,321 R444C probably damaging Het
Ttbk2 A G 2: 120,745,745 V848A probably benign Het
Ttn T C 2: 76,885,673 probably benign Het
Other mutations in Mindy2
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00770:Mindy2 APN 9 70631033 missense probably benign 0.05
IGL00774:Mindy2 APN 9 70631033 missense probably benign 0.05
IGL01889:Mindy2 APN 9 70631162 splice site probably benign
IGL02860:Mindy2 APN 9 70656544 missense probably damaging 1.00
R0100:Mindy2 UTSW 9 70607449 splice site probably benign
R0563:Mindy2 UTSW 9 70631052 missense possibly damaging 0.77
R1109:Mindy2 UTSW 9 70631079 nonsense probably null
R1446:Mindy2 UTSW 9 70607456 critical splice donor site probably null
R1736:Mindy2 UTSW 9 70631030 missense probably damaging 1.00
R2156:Mindy2 UTSW 9 70656592 missense probably benign 0.01
R4091:Mindy2 UTSW 9 70634060 missense probably damaging 0.98
R4290:Mindy2 UTSW 9 70631094 missense probably damaging 1.00
R4626:Mindy2 UTSW 9 70626781 missense probably damaging 1.00
R4791:Mindy2 UTSW 9 70634001 splice site probably null
R4973:Mindy2 UTSW 9 70605171 missense possibly damaging 0.86
R6077:Mindy2 UTSW 9 70631081 missense probably damaging 1.00
R6237:Mindy2 UTSW 9 70605198 missense possibly damaging 0.72
R6872:Mindy2 UTSW 9 70616762 critical splice donor site probably null
R7307:Mindy2 UTSW 9 70610959 missense possibly damaging 0.89
R7521:Mindy2 UTSW 9 70607510 missense probably benign 0.18
R7638:Mindy2 UTSW 9 70616859 missense probably damaging 1.00
Posted On2012-12-06