Incidental Mutation 'IGL00767:Nt5dc3'
ID12793
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Nt5dc3
Ensembl Gene ENSMUSG00000054027
Gene Name5'-nucleotidase domain containing 3
SynonymsGnn, C630002B14Rik
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL00767
Quality Score
Status
Chromosome10
Chromosomal Location86779005-86838389 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to A at 86820273 bp
ZygosityHeterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s): [ENSMUST00000099396]
Predicted Effect probably benign
Transcript: ENSMUST00000099396
SMART Domains Protein: ENSMUSP00000096994
Gene: ENSMUSG00000054027

DomainStartEndE-ValueType
low complexity region 5 25 N/A INTRINSIC
Pfam:5_nucleotid 83 526 1.8e-159 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000218792
Predicted Effect probably benign
Transcript: ENSMUST00000218802
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 20 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2810474O19Rik T C 6: 149,334,750 probably benign Het
Anpep A C 7: 79,840,890 S293A probably benign Het
Dgkh T A 14: 78,587,261 probably benign Het
Dlg5 T A 14: 24,165,285 T657S probably damaging Het
Hpf1 A G 8: 60,896,802 I155V probably benign Het
Il12rb2 T C 6: 67,303,562 I554V possibly damaging Het
Mindy2 A G 9: 70,634,003 probably null Het
Nostrin A G 2: 69,175,775 T268A probably benign Het
Npy6r A G 18: 44,276,318 T269A probably benign Het
Osgin2 G A 4: 16,006,377 H106Y probably damaging Het
Pdlim3 G A 8: 45,896,790 G46R probably damaging Het
Pdpk1 T G 17: 24,106,861 K147N possibly damaging Het
Pfkfb3 T C 2: 11,488,754 D137G probably damaging Het
Polg G A 7: 79,451,925 P1048S probably damaging Het
Ptcd3 A T 6: 71,903,448 I97K probably damaging Het
Serpinb10 G T 1: 107,536,077 V30F possibly damaging Het
Stk17b A G 1: 53,764,023 probably benign Het
Tll1 G A 8: 64,071,321 R444C probably damaging Het
Ttbk2 A G 2: 120,745,745 V848A probably benign Het
Ttn T C 2: 76,885,673 probably benign Het
Other mutations in Nt5dc3
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00476:Nt5dc3 APN 10 86833974 unclassified probably null
IGL01318:Nt5dc3 APN 10 86825225 missense possibly damaging 0.69
IGL01369:Nt5dc3 APN 10 86820275 splice site probably benign
IGL01376:Nt5dc3 APN 10 86834164 missense probably benign 0.05
IGL01568:Nt5dc3 APN 10 86833938 missense probably benign 0.02
IGL02286:Nt5dc3 APN 10 86820780 splice site probably benign
IGL02692:Nt5dc3 APN 10 86804778 splice site probably null
R0372:Nt5dc3 UTSW 10 86825291 missense possibly damaging 0.82
R0714:Nt5dc3 UTSW 10 86812374 missense probably damaging 1.00
R1755:Nt5dc3 UTSW 10 86824251 missense probably damaging 1.00
R1888:Nt5dc3 UTSW 10 86834062 missense possibly damaging 0.66
R1888:Nt5dc3 UTSW 10 86834062 missense possibly damaging 0.66
R3973:Nt5dc3 UTSW 10 86824236 missense probably damaging 1.00
R4097:Nt5dc3 UTSW 10 86833956 missense probably benign 0.01
R4871:Nt5dc3 UTSW 10 86817077 missense probably damaging 1.00
R5286:Nt5dc3 UTSW 10 86804792 missense probably benign 0.08
R5482:Nt5dc3 UTSW 10 86811531 missense probably damaging 1.00
R5530:Nt5dc3 UTSW 10 86820993 missense probably damaging 0.99
R5861:Nt5dc3 UTSW 10 86815874 missense probably damaging 1.00
R6260:Nt5dc3 UTSW 10 86811531 missense probably damaging 1.00
Posted On2012-12-06