Incidental Mutation 'IGL00709:Prelid2'
ID13154
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Prelid2
Ensembl Gene ENSMUSG00000056671
Gene NamePRELI domain containing 2
SynonymsC330008K14Rik, 1700003A01Rik
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL00709
Quality Score
Status
Chromosome18
Chromosomal Location41875696-41951194 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 41912423 bp
ZygosityHeterozygous
Amino Acid Change Asparagine to Tyrosine at position 141 (N141Y)
Ref Sequence ENSEMBL: ENSMUSP00000064661 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000070949]
Predicted Effect probably damaging
Transcript: ENSMUST00000070949
AA Change: N141Y

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
SMART Domains Protein: ENSMUSP00000064661
Gene: ENSMUSG00000056671
AA Change: N141Y

DomainStartEndE-ValueType
Pfam:PRELI 16 173 2.8e-51 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 11 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Atp6v1d T C 12: 78,849,754 H113R probably benign Het
Cd59a A G 2: 104,114,080 N91S probably benign Het
Ddx21 C A 10: 62,598,402 E193* probably null Het
Mink1 T A 11: 70,613,019 I1255N probably damaging Het
Orc1 G T 4: 108,590,778 probably null Het
Rad50 A G 11: 53,669,642 L1051S possibly damaging Het
Sidt1 C T 16: 44,262,011 probably benign Het
Slc25a24 A G 3: 109,159,354 K275E probably damaging Het
Stx19 A G 16: 62,822,580 N253S probably benign Het
Tanc2 A G 11: 105,798,795 Y261C probably damaging Het
Wdr62 A G 7: 30,242,061 L706P probably benign Het
Other mutations in Prelid2
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01731:Prelid2 APN 18 41937649 missense probably benign 0.03
G1patch:Prelid2 UTSW 18 41912449 missense possibly damaging 0.82
R0217:Prelid2 UTSW 18 41935252 splice site probably benign
R0556:Prelid2 UTSW 18 41951180 start gained probably benign
R0627:Prelid2 UTSW 18 41937652 missense possibly damaging 0.50
R0848:Prelid2 UTSW 18 41935224 missense probably damaging 0.98
R1522:Prelid2 UTSW 18 41881267 missense probably benign
R3919:Prelid2 UTSW 18 41937675 missense possibly damaging 0.79
R4131:Prelid2 UTSW 18 41951159 missense possibly damaging 0.94
R4422:Prelid2 UTSW 18 41912396 missense probably benign 0.01
R4892:Prelid2 UTSW 18 41951144 missense possibly damaging 0.86
R6062:Prelid2 UTSW 18 41912465 missense probably benign 0.00
R6725:Prelid2 UTSW 18 41912449 missense possibly damaging 0.82
R7276:Prelid2 UTSW 18 41912422 missense possibly damaging 0.65
R7739:Prelid2 UTSW 18 41912368 critical splice donor site probably null
R7941:Prelid2 UTSW 18 41932751 nonsense probably null
R8093:Prelid2 UTSW 18 41932635 missense probably damaging 1.00
R8202:Prelid2 UTSW 18 41932737 missense possibly damaging 0.95
R8393:Prelid2 UTSW 18 41881248 missense probably benign 0.08
Posted On2012-12-06