Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00797:Prr11'

13185

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Prr11

Ensembl Gene

ENSMUSG00000020493

Gene Name

proline rich 11

Synonyms

B930067F20Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.069) question?

Stock #

IGL00797

Quality Score

Status

Chromosome

Chromosomal Location

86979979-86999534 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 86989505 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Valine at position 289 (I289V)

Ref Sequence

ENSEMBL: ENSMUSP00000060803 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000051395]

AlphaFold

Q8BHE0

Predicted Effect

probably benign
Transcript: ENSMUST00000051395
AA Change: I289V

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000060803
Gene: ENSMUSG00000020493
AA Change: I289V

Domain	Start	End	E-Value	Type
low complexity region	3	25	N/A	INTRINSIC
low complexity region	28	42	N/A	INTRINSIC
low complexity region	135	152	N/A	INTRINSIC
low complexity region	184	212	N/A	INTRINSIC
low complexity region	350	363	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 9 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
B4galt7	A	T	13: 55,755,006 (GRCm39)		probably benign	Het
Bltp2	A	G	11: 78,163,976 (GRCm39)	T1106A	probably benign	Het
Camsap3	T	A	8: 3,652,115 (GRCm39)		probably benign	Het
Cfap206	C	T	4: 34,721,562 (GRCm39)	S162N	probably damaging	Het
Cpeb2	C	T	5: 43,438,790 (GRCm39)	T844I	probably damaging	Het
Fbxl5	T	A	5: 43,915,743 (GRCm39)	L555F	probably damaging	Het
Gsn	G	T	2: 35,174,049 (GRCm39)	D53Y	probably damaging	Het
Psg22	A	G	7: 18,452,200 (GRCm39)	D39G	probably benign	Het
Smgc	A	T	15: 91,738,746 (GRCm39)		probably benign	Het

Other mutations in Prr11

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02106:Prr11	APN	11	86,994,141 (GRCm39)	splice site	probably benign
IGL02733:Prr11	APN	11	86,994,371 (GRCm39)	missense	possibly damaging	0.90
IGL03052:Prr11	APN	11	86,994,478 (GRCm39)	missense	possibly damaging	0.66
IGL03288:Prr11	APN	11	86,987,787 (GRCm39)	critical splice donor site	probably null
R1931:Prr11	UTSW	11	86,996,868 (GRCm39)	nonsense	probably null
R1972:Prr11	UTSW	11	86,989,580 (GRCm39)	missense	possibly damaging	0.94
R1981:Prr11	UTSW	11	86,994,116 (GRCm39)	missense	probably damaging	0.99
R4499:Prr11	UTSW	11	86,989,533 (GRCm39)	missense	possibly damaging	0.82
R4500:Prr11	UTSW	11	86,989,533 (GRCm39)	missense	possibly damaging	0.82
R4837:Prr11	UTSW	11	86,989,517 (GRCm39)	missense	probably benign	0.00
R6163:Prr11	UTSW	11	86,994,454 (GRCm39)	missense	possibly damaging	0.92
R6172:Prr11	UTSW	11	86,994,449 (GRCm39)	missense	probably benign	0.02
R6389:Prr11	UTSW	11	86,989,564 (GRCm39)	missense	possibly damaging	0.92
R6469:Prr11	UTSW	11	86,988,003 (GRCm39)	missense	possibly damaging	0.46
R6505:Prr11	UTSW	11	86,996,950 (GRCm39)	nonsense	probably null
R7372:Prr11	UTSW	11	86,989,600 (GRCm39)	missense	probably benign	0.01
R7710:Prr11	UTSW	11	86,994,433 (GRCm39)	missense	probably benign	0.10
R7983:Prr11	UTSW	11	86,982,637 (GRCm39)	missense	possibly damaging	0.90
R8798:Prr11	UTSW	11	86,996,881 (GRCm39)	missense	unknown
R9065:Prr11	UTSW	11	86,992,249 (GRCm39)	missense	probably damaging	0.96
R9416:Prr11	UTSW	11	86,992,254 (GRCm39)	nonsense	probably null
R9602:Prr11	UTSW	11	86,987,998 (GRCm39)	missense	possibly damaging	0.90
R9752:Prr11	UTSW	11	86,994,416 (GRCm39)	missense	possibly damaging	0.66
Z1176:Prr11	UTSW	11	86,987,968 (GRCm39)	missense	possibly damaging	0.46

Posted On

2012-12-06