Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL00814:Psg23'

13200

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Psg23

Ensembl Gene

ENSMUSG00000074359

Gene Name

pregnancy-specific glycoprotein 23

Synonyms

1620401C02Rik

Accession Numbers

Is this an essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL00814

Quality Score

Status

Chromosome

Chromosomal Location

18606343-18616501 bp(-) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

C to T at 18614683 bp

Zygosity

Heterozygous

Amino Acid Change

Tryptophan to Stop codon at position 66 (W66*)

Ref Sequence

ENSEMBL: ENSMUSP00000056586 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000057810]

Predicted Effect

probably null
Transcript: ENSMUST00000057810
AA Change: W66*

SMART Domains

Protein: ENSMUSP00000056586
Gene: ENSMUSG00000074359
AA Change: W66*

Domain	Start	End	E-Value	Type
IG	39	138	2.03e-4	SMART
IG	159	260	4.16e-1	SMART
IG	276	375	1.25e-4	SMART
IGc2	393	457	4.7e-9	SMART

Coding Region Coverage

Validation Efficiency

MGI Phenotype

PHENOTYPE: Mice homozygous for this spontaneous mutation display no phenotypic abnormalities. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 17 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Cops6	G	T	5: 138,163,378	R58L	probably damaging	Het
Elmo1	T	A	13: 20,286,724	M262K	probably damaging	Het
Faim	G	A	9: 98,992,165	G15R	probably damaging	Het
Gria4	A	T	9: 4,472,202	M429K	probably damaging	Het
Hipk2	G	A	6: 38,818,549	R262W	probably damaging	Het
Kif23	A	T	9: 61,937,107	I143K	possibly damaging	Het
Mbtd1	T	A	11: 93,943,840	S615T	possibly damaging	Het
Nlrp9c	C	T	7: 26,384,750	S468N	probably benign	Het
Nt5c2	A	T	19: 46,897,648	D212E	probably benign	Het
Olfr596	A	T	7: 103,309,807	I29L	probably benign	Het
Pck2	T	C	14: 55,548,299		probably benign	Het
Pdcd6ip	T	C	9: 113,687,653	Q230R	probably damaging	Het
Pomk	T	C	8: 25,983,596	T110A	probably benign	Het
Rnf144b	T	C	13: 47,220,488		probably benign	Het
Sppl2c	G	A	11: 104,186,979	G202S	possibly damaging	Het
Thnsl2	A	C	6: 71,139,883	L95R	probably damaging	Het
Ttn	A	G	2: 76,807,167	V12248A	probably benign	Het

Other mutations in Psg23

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01309:Psg23	APN	7	18614540	missense	probably damaging	1.00
IGL01736:Psg23	APN	7	18612197	missense	possibly damaging	0.76
IGL02142:Psg23	APN	7	18610420	missense	probably benign	0.01
IGL02728:Psg23	APN	7	18606928	missense	probably benign	0.02
IGL03080:Psg23	APN	7	18606985	missense	probably damaging	1.00
IGL03130:Psg23	APN	7	18610416	missense	probably benign	0.25
R0113:Psg23	UTSW	7	18612002	missense	probably benign	0.31
R0137:Psg23	UTSW	7	18614633	missense	probably benign	0.00
R0544:Psg23	UTSW	7	18614682	missense	probably damaging	1.00
R1368:Psg23	UTSW	7	18614720	missense	probably benign	0.13
R1840:Psg23	UTSW	7	18610438	missense	possibly damaging	0.67
R1869:Psg23	UTSW	7	18614618	missense	probably benign	0.09
R1875:Psg23	UTSW	7	18610450	missense	probably benign	0.10
R2041:Psg23	UTSW	7	18614778	missense	possibly damaging	0.78
R2096:Psg23	UTSW	7	18614743	missense	probably damaging	1.00
R3110:Psg23	UTSW	7	18610444	missense	possibly damaging	0.72
R3112:Psg23	UTSW	7	18610444	missense	possibly damaging	0.72
R3790:Psg23	UTSW	7	18612201	missense	probably benign	0.00
R3892:Psg23	UTSW	7	18612041	missense	probably damaging	1.00
R4074:Psg23	UTSW	7	18607118	missense	possibly damaging	0.66
R4200:Psg23	UTSW	7	18612065	missense	probably damaging	1.00
R4865:Psg23	UTSW	7	18612114	missense	probably benign	0.14
R5337:Psg23	UTSW	7	18612072	missense	probably benign	0.00
R6016:Psg23	UTSW	7	18612187	missense	probably benign	0.00
R6951:Psg23	UTSW	7	18614711	missense	probably damaging	1.00
R7033:Psg23	UTSW	7	18614744	missense	possibly damaging	0.82
R7212:Psg23	UTSW	7	18607139	missense	probably benign	0.00
R7427:Psg23	UTSW	7	18611983	splice site	probably null
R7527:Psg23	UTSW	7	18614774	missense	probably damaging	1.00
R7814:Psg23	UTSW	7	18606914	makesense	probably null
R7864:Psg23	UTSW	7	18610510	missense	possibly damaging	0.87
R7897:Psg23	UTSW	7	18607183	missense	possibly damaging	0.83
R8155:Psg23	UTSW	7	18612254	missense	probably damaging	1.00
R8358:Psg23	UTSW	7	18614597	missense	probably benign	0.00

Posted On

2012-12-06