Incidental Mutation 'IGL00686:Samt4'
ID 13912
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Samt4
Ensembl Gene ENSMUSG00000025051
Gene Name spermatogenesis associated multipass transmembrane protein 4
Synonyms 4930542N07Rik
Accession Numbers
Essential gene? Not available question?
Stock # IGL00686
Quality Score
Status
Chromosome X
Chromosomal Location 153264998-153267678 bp(+) (GRCm39)
Type of Mutation missense
DNA Base Change (assembly) C to T at 153267128 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change Threonine to Isoleucine at position 89 (T89I)
Ref Sequence ENSEMBL: ENSMUSP00000026029 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000026029]
AlphaFold Q9D4X6
Predicted Effect probably benign
Transcript: ENSMUST00000026029
AA Change: T89I

PolyPhen 2 Score 0.109 (Sensitivity: 0.93; Specificity: 0.86)
SMART Domains Protein: ENSMUSP00000026029
Gene: ENSMUSG00000025051
AA Change: T89I

DomainStartEndE-ValueType
Blast:Tryp_SPc 12 164 5e-36 BLAST
transmembrane domain 186 208 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 6 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4932438H23Rik A G 16: 90,852,489 (GRCm39) S216P possibly damaging Het
Btk A G X: 133,460,013 (GRCm39) Y152H probably damaging Het
Casp8ap2 A G 4: 32,641,433 (GRCm39) D829G probably damaging Het
Fam135b A G 15: 71,334,168 (GRCm39) S1009P probably benign Het
Glt8d2 T A 10: 82,487,347 (GRCm39) N298Y possibly damaging Het
Tlcd3b C T 7: 126,424,175 (GRCm39) probably benign Het
Other mutations in Samt4
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02412:Samt4 APN X 153,267,118 (GRCm39) missense probably damaging 1.00
Posted On 2012-12-06