Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00709:Sidt1'

14014

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Sidt1

Ensembl Gene

ENSMUSG00000022696

Gene Name

SID1 transmembrane family, member 1

Synonyms

B830021E24Rik

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL00709

Quality Score

Status

Chromosome

Chromosomal Location

44060543-44153559 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

C to T at 44082374 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000115372 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000047446] [ENSMUST00000127567] [ENSMUST00000136381]

AlphaFold

Q6AXF6

Predicted Effect

probably benign
Transcript: ENSMUST00000047446

SMART Domains

Protein: ENSMUSP00000038433
Gene: ENSMUSG00000022696

Domain	Start	End	E-Value	Type
signal peptide	1	19	N/A	INTRINSIC
low complexity region	36	50	N/A	INTRINSIC
Pfam:SID-1_RNA_chan	184	832	1.8e-290	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000127567

SMART Domains

Protein: ENSMUSP00000116201
Gene: ENSMUSG00000022696

Domain	Start	End	E-Value	Type
Pfam:SID-1_RNA_chan	2	445	8.6e-198	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000136381

SMART Domains

Protein: ENSMUSP00000115372
Gene: ENSMUSG00000022696

Domain	Start	End	E-Value	Type
signal peptide	1	19	N/A	INTRINSIC
low complexity region	36	50	N/A	INTRINSIC
Pfam:SID-1_RNA_chan	184	827	1.3e-251	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 11 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Atp6v1d	T	C	12: 78,896,528 (GRCm39)	H113R	probably benign	Het
Cd59a	A	G	2: 103,944,425 (GRCm39)	N91S	probably benign	Het
Ddx21	C	A	10: 62,434,181 (GRCm39)	E193*	probably null	Het
Mink1	T	A	11: 70,503,845 (GRCm39)	I1255N	probably damaging	Het
Orc1	G	T	4: 108,447,975 (GRCm39)		probably null	Het
Prelid2	T	A	18: 42,045,488 (GRCm39)	N141Y	probably damaging	Het
Rad50	A	G	11: 53,560,469 (GRCm39)	L1051S	possibly damaging	Het
Slc25a24	A	G	3: 109,066,670 (GRCm39)	K275E	probably damaging	Het
Stx19	A	G	16: 62,642,943 (GRCm39)	N253S	probably benign	Het
Tanc2	A	G	11: 105,689,621 (GRCm39)	Y261C	probably damaging	Het
Wdr62	A	G	7: 29,941,486 (GRCm39)	L706P	probably benign	Het

Other mutations in Sidt1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01103:Sidt1	APN	16	44,063,906 (GRCm39)	nonsense	probably null
IGL01725:Sidt1	APN	16	44,104,645 (GRCm39)	missense	probably benign	0.06
IGL02000:Sidt1	APN	16	44,106,732 (GRCm39)	missense	probably damaging	0.98
IGL02266:Sidt1	APN	16	44,075,348 (GRCm39)	missense	possibly damaging	0.90
IGL02309:Sidt1	APN	16	44,075,343 (GRCm39)	missense	probably benign	0.00
IGL02898:Sidt1	APN	16	44,102,858 (GRCm39)	missense	possibly damaging	0.87
R0282:Sidt1	UTSW	16	44,102,249 (GRCm39)	missense	possibly damaging	0.79
R0525:Sidt1	UTSW	16	44,079,809 (GRCm39)	missense	possibly damaging	0.64
R0927:Sidt1	UTSW	16	44,063,895 (GRCm39)	missense	probably benign	0.00
R1806:Sidt1	UTSW	16	44,102,234 (GRCm39)	missense	possibly damaging	0.46
R1911:Sidt1	UTSW	16	44,102,234 (GRCm39)	missense	possibly damaging	0.81
R3843:Sidt1	UTSW	16	44,104,587 (GRCm39)	missense	probably benign	0.04
R3848:Sidt1	UTSW	16	44,076,322 (GRCm39)	intron	probably benign
R4023:Sidt1	UTSW	16	44,102,249 (GRCm39)	missense	possibly damaging	0.79
R4026:Sidt1	UTSW	16	44,102,249 (GRCm39)	missense	possibly damaging	0.79
R4495:Sidt1	UTSW	16	44,102,841 (GRCm39)	missense	probably damaging	1.00
R4603:Sidt1	UTSW	16	44,075,389 (GRCm39)	missense	probably damaging	0.98
R4707:Sidt1	UTSW	16	44,090,221 (GRCm39)	nonsense	probably null
R5322:Sidt1	UTSW	16	44,101,985 (GRCm39)	intron	probably benign
R5921:Sidt1	UTSW	16	44,094,098 (GRCm39)	splice site	probably benign
R5980:Sidt1	UTSW	16	44,083,675 (GRCm39)	nonsense	probably null
R5982:Sidt1	UTSW	16	44,082,071 (GRCm39)	missense	probably damaging	1.00
R6063:Sidt1	UTSW	16	44,079,829 (GRCm39)	missense	probably benign	0.01
R6337:Sidt1	UTSW	16	44,121,298 (GRCm39)	splice site	probably null
R6392:Sidt1	UTSW	16	44,111,657 (GRCm39)	missense	possibly damaging	0.47
R6855:Sidt1	UTSW	16	44,065,706 (GRCm39)	missense	probably null	1.00
R7092:Sidt1	UTSW	16	44,120,192 (GRCm39)	missense	possibly damaging	0.89
R7099:Sidt1	UTSW	16	44,063,860 (GRCm39)	missense	probably damaging	1.00
R7448:Sidt1	UTSW	16	44,106,763 (GRCm39)	nonsense	probably null
R7574:Sidt1	UTSW	16	44,079,848 (GRCm39)	missense	probably damaging	1.00
R8265:Sidt1	UTSW	16	44,088,250 (GRCm39)	missense	possibly damaging	0.79
R8379:Sidt1	UTSW	16	44,106,755 (GRCm39)	missense	probably benign	0.14
R8460:Sidt1	UTSW	16	44,107,705 (GRCm39)	nonsense	probably null
R8480:Sidt1	UTSW	16	44,065,529 (GRCm39)	missense	probably damaging	1.00
R8762:Sidt1	UTSW	16	44,152,707 (GRCm39)	missense	probably benign	0.16
R8954:Sidt1	UTSW	16	44,082,390 (GRCm39)	missense	probably benign	0.04
R8974:Sidt1	UTSW	16	44,101,980 (GRCm39)	makesense	probably null
R9362:Sidt1	UTSW	16	44,078,316 (GRCm39)	missense	possibly damaging	0.96
R9451:Sidt1	UTSW	16	44,075,392 (GRCm39)	critical splice acceptor site	probably null
R9669:Sidt1	UTSW	16	44,102,243 (GRCm39)	missense	probably damaging	1.00
R9737:Sidt1	UTSW	16	44,102,243 (GRCm39)	missense	probably damaging	1.00
Z1176:Sidt1	UTSW	16	44,079,845 (GRCm39)	missense	possibly damaging	0.90
Z1191:Sidt1	UTSW	16	44,078,294 (GRCm39)	critical splice donor site	probably null

Posted On

2012-12-06