Incidental Mutation 'IGL00821:Slc41a2'
ID14099
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Slc41a2
Ensembl Gene ENSMUSG00000034591
Gene Namesolute carrier family 41, member 2
SynonymsA230035L05Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.218) question?
Stock #IGL00821
Quality Score
Status
Chromosome10
Chromosomal Location83230848-83337882 bp(-) (GRCm38)
Type of Mutationunclassified
DNA Base Change (assembly) A to G at 83313530 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000116482 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000039956] [ENSMUST00000126617] [ENSMUST00000154730] [ENSMUST00000154926]
Predicted Effect probably benign
Transcript: ENSMUST00000039956
SMART Domains Protein: ENSMUSP00000036690
Gene: ENSMUSG00000034591

DomainStartEndE-ValueType
transmembrane domain 159 181 N/A INTRINSIC
Pfam:MgtE 200 334 8.7e-24 PFAM
transmembrane domain 346 368 N/A INTRINSIC
transmembrane domain 375 397 N/A INTRINSIC
Pfam:MgtE 414 557 2.9e-32 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000126617
Predicted Effect probably benign
Transcript: ENSMUST00000154730
Predicted Effect probably benign
Transcript: ENSMUST00000154926
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 28 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Cad T C 5: 31,061,484 Y550H probably damaging Het
Cep350 A G 1: 155,862,204 V2631A probably benign Het
Cpa2 A G 6: 30,564,412 D414G probably benign Het
Dhx38 T C 8: 109,555,654 I714V probably benign Het
Dis3 T C 14: 99,091,486 I277V probably benign Het
Espl1 T C 15: 102,299,813 L418P probably damaging Het
F7 A G 8: 13,028,802 T78A probably benign Het
Faim G A 9: 98,992,165 G15R probably damaging Het
Golga3 C A 5: 110,204,933 H897N possibly damaging Het
Itgae T A 11: 73,123,148 D724E probably damaging Het
Klb A T 5: 65,372,149 Y340F probably damaging Het
Kmt2b A T 7: 30,570,613 L2436Q probably damaging Het
Krt17 A G 11: 100,260,631 L112P probably damaging Het
Lrp2 T A 2: 69,459,516 N3660Y probably damaging Het
Mia2 T C 12: 59,170,320 probably null Het
Myh2 C T 11: 67,197,397 probably benign Het
Nr2f1 A G 13: 78,198,114 probably benign Het
Odf2l T A 3: 145,150,987 S568T probably damaging Het
Parl G A 16: 20,298,208 P80S probably damaging Het
Ppfibp2 T G 7: 107,729,876 F531V probably damaging Het
Prpf40b A G 15: 99,316,501 E854G probably benign Het
Rere A G 4: 150,619,463 K1551E probably damaging Het
Sacm1l A T 9: 123,570,549 Q302L possibly damaging Het
Smchd1 T C 17: 71,398,623 T994A possibly damaging Het
Ubxn7 G A 16: 32,369,398 D125N probably damaging Het
Zfp667 A G 7: 6,305,397 N355D possibly damaging Het
Zfp839 T C 12: 110,865,007 probably null Het
Zfpm2 T A 15: 41,103,387 N957K probably damaging Het
Other mutations in Slc41a2
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02263:Slc41a2 APN 10 83313500 missense possibly damaging 0.82
IGL02338:Slc41a2 APN 10 83316591 missense possibly damaging 0.68
IGL02680:Slc41a2 APN 10 83283864 missense probably benign 0.20
IGL02703:Slc41a2 APN 10 83254847 missense probably damaging 1.00
IGL03039:Slc41a2 APN 10 83283858 missense probably benign 0.37
PIT4508001:Slc41a2 UTSW 10 83254880 missense probably damaging 0.99
R0326:Slc41a2 UTSW 10 83283746 missense probably damaging 1.00
R0470:Slc41a2 UTSW 10 83316222 missense possibly damaging 0.94
R0610:Slc41a2 UTSW 10 83283728 missense possibly damaging 0.75
R1708:Slc41a2 UTSW 10 83233732 missense probably damaging 1.00
R1765:Slc41a2 UTSW 10 83301266 missense probably damaging 1.00
R1870:Slc41a2 UTSW 10 83301165 nonsense probably null
R1875:Slc41a2 UTSW 10 83256085 missense probably damaging 1.00
R2008:Slc41a2 UTSW 10 83304303 critical splice donor site probably null
R2172:Slc41a2 UTSW 10 83283774 missense probably benign 0.00
R4193:Slc41a2 UTSW 10 83301221 missense probably damaging 0.97
R4789:Slc41a2 UTSW 10 83316456 missense probably damaging 1.00
R4861:Slc41a2 UTSW 10 83316458 missense probably damaging 0.99
R4861:Slc41a2 UTSW 10 83316458 missense probably damaging 0.99
R4913:Slc41a2 UTSW 10 83313420 missense probably damaging 1.00
R5012:Slc41a2 UTSW 10 83301263 missense probably benign 0.02
R5140:Slc41a2 UTSW 10 83297291 missense probably damaging 0.98
R5189:Slc41a2 UTSW 10 83313411 splice site probably null
R5410:Slc41a2 UTSW 10 83281368 critical splice donor site probably null
R5748:Slc41a2 UTSW 10 83297159 missense probably benign 0.00
R5808:Slc41a2 UTSW 10 83313498 missense probably benign 0.29
R6124:Slc41a2 UTSW 10 83297252 missense probably damaging 1.00
R6292:Slc41a2 UTSW 10 83254926 missense probably damaging 0.99
R6511:Slc41a2 UTSW 10 83283788 missense probably damaging 0.99
R6793:Slc41a2 UTSW 10 83301158 splice site probably null
R6970:Slc41a2 UTSW 10 83316096 missense possibly damaging 0.53
R7584:Slc41a2 UTSW 10 83316789 splice site probably benign
R7752:Slc41a2 UTSW 10 83256041 missense possibly damaging 0.73
R8289:Slc41a2 UTSW 10 83301180 missense probably benign 0.06
Posted On2012-12-06