Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL00685:Tas2r102'

14369

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tas2r102

Ensembl Gene

ENSMUSG00000056901

Gene Name

taste receptor, type 2, member 102

Synonyms

Tas2r2, mt2r51, mGR02, STC 9-7

Accession Numbers

Is this an essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL00685

Quality Score

Status

Chromosome

Chromosomal Location

132762131-132763174 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 132762525 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Serine at position 132 (N132S)

Ref Sequence

ENSEMBL: ENSMUSP00000068332 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000069268]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000069268
AA Change: N132S

PolyPhen 2 Score 0.579 (Sensitivity: 0.88; Specificity: 0.91)

SMART Domains

Protein: ENSMUSP00000068332
Gene: ENSMUSG00000056901
AA Change: N132S

Domain	Start	End	E-Value	Type
Pfam:TAS2R	21	317	3.6e-100	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000204939

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 5 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Foxn2	T	C	17: 88,462,877	S51P	probably benign	Het
Fra10ac1	T	A	19: 38,201,564	K217N	probably damaging	Het
Klra9	T	A	6: 130,182,406	I215F	probably damaging	Het
Manea	A	G	4: 26,340,578	L128P	probably damaging	Het
Odf2l	A	T	3: 145,127,873	N138Y	possibly damaging	Het

Other mutations in Tas2r102

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01777:Tas2r102	APN	6	132762852	missense	probably damaging	0.98
IGL01956:Tas2r102	APN	6	132762453	nonsense	probably null
IGL02126:Tas2r102	APN	6	132762644	missense	probably damaging	1.00
IGL02650:Tas2r102	APN	6	132762210	missense	probably null	0.00
R0483:Tas2r102	UTSW	6	132762365	missense	probably damaging	1.00
R0573:Tas2r102	UTSW	6	132762673	missense	probably damaging	0.98
R0726:Tas2r102	UTSW	6	132762452	missense	probably damaging	1.00
R1777:Tas2r102	UTSW	6	132762291	missense	probably benign	0.08
R3615:Tas2r102	UTSW	6	132762818	nonsense	probably null
R3616:Tas2r102	UTSW	6	132762818	nonsense	probably null
R4556:Tas2r102	UTSW	6	132762915	missense	probably damaging	1.00
R4633:Tas2r102	UTSW	6	132762679	missense	possibly damaging	0.87
R4724:Tas2r102	UTSW	6	132762557	missense	probably damaging	0.97
R5268:Tas2r102	UTSW	6	132762397	missense	probably damaging	0.98
R5494:Tas2r102	UTSW	6	132763143	missense	probably benign	0.12

Posted On

2012-12-06