Incidental Mutation 'IGL00685:Tas2r102'
| ID |
14369 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Tas2r102
|
| Ensembl Gene |
ENSMUSG00000056901 |
| Gene Name |
taste receptor, type 2, member 102 |
| Synonyms |
STC 9-7, mt2r51, mGR02, Tas2r2 |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
IGL00685
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
6 |
| Chromosomal Location |
132739094-132740137 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 132739488 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Serine
at position 132
(N132S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000068332
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000069268]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000069268
AA Change: N132S
PolyPhen 2
Score 0.579 (Sensitivity: 0.88; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000068332
Gene: ENSMUSG00000056901
AA Change: N132S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
21 |
317 |
3.6e-100 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000204939
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 5 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Foxn2 |
T |
C |
17: 88,770,305 (GRCm39) |
S51P |
probably benign |
Het |
| Fra10ac1 |
T |
A |
19: 38,190,012 (GRCm39) |
K217N |
probably damaging |
Het |
| Klra9 |
T |
A |
6: 130,159,369 (GRCm39) |
I215F |
probably damaging |
Het |
| Manea |
A |
G |
4: 26,340,578 (GRCm39) |
L128P |
probably damaging |
Het |
| Odf2l |
A |
T |
3: 144,833,634 (GRCm39) |
N138Y |
possibly damaging |
Het |
|
| Other mutations in Tas2r102 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01777:Tas2r102
|
APN |
6 |
132,739,815 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01956:Tas2r102
|
APN |
6 |
132,739,416 (GRCm39) |
nonsense |
probably null |
|
|
IGL02126:Tas2r102
|
APN |
6 |
132,739,607 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02650:Tas2r102
|
APN |
6 |
132,739,173 (GRCm39) |
missense |
probably null |
0.00 |
|
R0483:Tas2r102
|
UTSW |
6 |
132,739,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0573:Tas2r102
|
UTSW |
6 |
132,739,636 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0726:Tas2r102
|
UTSW |
6 |
132,739,415 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1777:Tas2r102
|
UTSW |
6 |
132,739,254 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3615:Tas2r102
|
UTSW |
6 |
132,739,781 (GRCm39) |
nonsense |
probably null |
|
|
R3616:Tas2r102
|
UTSW |
6 |
132,739,781 (GRCm39) |
nonsense |
probably null |
|
|
R4556:Tas2r102
|
UTSW |
6 |
132,739,878 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4633:Tas2r102
|
UTSW |
6 |
132,739,642 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4724:Tas2r102
|
UTSW |
6 |
132,739,520 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5268:Tas2r102
|
UTSW |
6 |
132,739,360 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5494:Tas2r102
|
UTSW |
6 |
132,740,106 (GRCm39) |
missense |
probably benign |
0.12 |
|
| Posted On |
2012-12-06 |
Incidental Mutation