Incidental Mutation 'IGL00685:Tas2r102'
ID 14369
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Tas2r102
Ensembl Gene ENSMUSG00000056901
Gene Name taste receptor, type 2, member 102
Synonyms STC 9-7, mt2r51, mGR02, Tas2r2
Accession Numbers
Essential gene? Non essential (E-score: 0.000) question?
Stock # IGL00685
Quality Score
Chromosome 6
Chromosomal Location 132739094-132740137 bp(+) (GRCm39)
Type of Mutation missense
DNA Base Change (assembly) A to G at 132739488 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change Asparagine to Serine at position 132 (N132S)
Ref Sequence ENSEMBL: ENSMUSP00000068332 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000069268]
AlphaFold no structure available at present
Predicted Effect possibly damaging
Transcript: ENSMUST00000069268
AA Change: N132S

PolyPhen 2 Score 0.579 (Sensitivity: 0.88; Specificity: 0.91)
SMART Domains Protein: ENSMUSP00000068332
Gene: ENSMUSG00000056901
AA Change: N132S

Pfam:TAS2R 21 317 3.6e-100 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000204939
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 5 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Foxn2 T C 17: 88,770,305 (GRCm39) S51P probably benign Het
Fra10ac1 T A 19: 38,190,012 (GRCm39) K217N probably damaging Het
Klra9 T A 6: 130,159,369 (GRCm39) I215F probably damaging Het
Manea A G 4: 26,340,578 (GRCm39) L128P probably damaging Het
Odf2l A T 3: 144,833,634 (GRCm39) N138Y possibly damaging Het
Other mutations in Tas2r102
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01777:Tas2r102 APN 6 132,739,815 (GRCm39) missense probably damaging 0.98
IGL01956:Tas2r102 APN 6 132,739,416 (GRCm39) nonsense probably null
IGL02126:Tas2r102 APN 6 132,739,607 (GRCm39) missense probably damaging 1.00
IGL02650:Tas2r102 APN 6 132,739,173 (GRCm39) missense probably null 0.00
R0483:Tas2r102 UTSW 6 132,739,328 (GRCm39) missense probably damaging 1.00
R0573:Tas2r102 UTSW 6 132,739,636 (GRCm39) missense probably damaging 0.98
R0726:Tas2r102 UTSW 6 132,739,415 (GRCm39) missense probably damaging 1.00
R1777:Tas2r102 UTSW 6 132,739,254 (GRCm39) missense probably benign 0.08
R3615:Tas2r102 UTSW 6 132,739,781 (GRCm39) nonsense probably null
R3616:Tas2r102 UTSW 6 132,739,781 (GRCm39) nonsense probably null
R4556:Tas2r102 UTSW 6 132,739,878 (GRCm39) missense probably damaging 1.00
R4633:Tas2r102 UTSW 6 132,739,642 (GRCm39) missense possibly damaging 0.87
R4724:Tas2r102 UTSW 6 132,739,520 (GRCm39) missense probably damaging 0.97
R5268:Tas2r102 UTSW 6 132,739,360 (GRCm39) missense probably damaging 0.98
R5494:Tas2r102 UTSW 6 132,740,106 (GRCm39) missense probably benign 0.12
Posted On 2012-12-06