Incidental Mutation 'IGL00858:Tas2r113'
ID14370
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Tas2r113
Ensembl Gene ENSMUSG00000056926
Gene Nametaste receptor, type 2, member 113
SynonymsT2R13, mGR13, mt2r58, Tas2r13
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.062) question?
Stock #IGL00858
Quality Score
Status
Chromosome6
Chromosomal Location132893011-132893940 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) C to A at 132893152 bp
ZygosityHeterozygous
Amino Acid Change Arginine to Serine at position 48 (R48S)
Ref Sequence ENSEMBL: ENSMUSP00000078044 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000079035]
Predicted Effect probably benign
Transcript: ENSMUST00000079035
AA Change: R48S

PolyPhen 2 Score 0.012 (Sensitivity: 0.96; Specificity: 0.78)
SMART Domains Protein: ENSMUSP00000078044
Gene: ENSMUSG00000056926
AA Change: R48S

DomainStartEndE-ValueType
Pfam:TAS2R 1 301 9.4e-78 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 24 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca4 G A 3: 122,173,888 V988M probably damaging Het
Afap1l1 G A 18: 61,736,854 T635M probably benign Het
B4galnt1 A G 10: 127,167,764 T199A probably benign Het
Ccdc105 T C 10: 78,750,569 D216G probably damaging Het
Ccdc183 T A 2: 25,609,771 M378L probably benign Het
Ccser1 C A 6: 61,810,665 S134* probably null Het
Cluh A G 11: 74,659,605 K248E possibly damaging Het
Cpa6 T A 1: 10,483,994 R129S probably damaging Het
Cyp2c29 T A 19: 39,307,656 V138D probably damaging Het
Cyp4f14 A G 17: 32,911,718 probably benign Het
Dock10 T C 1: 80,568,003 N841S possibly damaging Het
Dtwd2 A T 18: 49,728,385 I98N probably damaging Het
Fut10 G T 8: 31,235,705 V163F probably damaging Het
Ifi44 T A 3: 151,749,580 M3L probably benign Het
Mtch1 C T 17: 29,340,456 D74N probably damaging Het
Nav3 A G 10: 109,742,632 V1588A probably damaging Het
Pbk T C 14: 65,811,924 probably benign Het
Ptcd1 A T 5: 145,151,282 probably benign Het
Rapgef4 A T 2: 72,198,897 I438F probably damaging Het
Tnn C T 1: 160,088,392 probably null Het
Tnnt2 G A 1: 135,851,702 V277I probably damaging Het
Twnk G T 19: 45,007,626 W166L probably benign Het
Utp20 G A 10: 88,809,125 L580F possibly damaging Het
Utp20 T A 10: 88,809,138 E575D probably benign Het
Other mutations in Tas2r113
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01118:Tas2r113 APN 6 132893315 missense probably benign 0.00
IGL01366:Tas2r113 APN 6 132893797 missense probably benign 0.06
IGL01955:Tas2r113 APN 6 132893854 missense probably benign
IGL02629:Tas2r113 APN 6 132893336 missense probably damaging 1.00
IGL02681:Tas2r113 APN 6 132893367 missense probably damaging 1.00
IGL02883:Tas2r113 APN 6 132893419 missense probably damaging 1.00
R0002:Tas2r113 UTSW 6 132893779 missense probably benign 0.21
R0309:Tas2r113 UTSW 6 132893378 missense probably damaging 1.00
R1700:Tas2r113 UTSW 6 132893792 missense possibly damaging 0.92
R1748:Tas2r113 UTSW 6 132893732 missense probably damaging 0.98
R1854:Tas2r113 UTSW 6 132893329 missense probably damaging 1.00
R1974:Tas2r113 UTSW 6 132893833 missense probably benign 0.00
R4697:Tas2r113 UTSW 6 132893516 missense probably benign 0.04
R4798:Tas2r113 UTSW 6 132893707 missense possibly damaging 0.69
R4816:Tas2r113 UTSW 6 132893782 missense probably benign 0.09
R4906:Tas2r113 UTSW 6 132893558 missense possibly damaging 0.69
R6005:Tas2r113 UTSW 6 132893696 missense probably benign 0.02
R6012:Tas2r113 UTSW 6 132893681 missense probably damaging 1.00
R6107:Tas2r113 UTSW 6 132893014 missense probably damaging 1.00
R6603:Tas2r113 UTSW 6 132893458 missense probably benign 0.01
R7263:Tas2r113 UTSW 6 132893576 missense possibly damaging 0.90
R7434:Tas2r113 UTSW 6 132893309 missense probably benign 0.03
R7759:Tas2r113 UTSW 6 132893927 missense possibly damaging 0.85
X0022:Tas2r113 UTSW 6 132893296 missense probably damaging 0.98
Posted On2012-12-06