Incidental Mutation 'IGL00592:Vmn1r79'
| ID |
14791 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r79
|
| Ensembl Gene |
ENSMUSG00000096735 |
| Gene Name |
vomeronasal 1 receptor 79 |
| Synonyms |
Gm9807 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.066)
|
| Stock # |
IGL00592
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
11910120-11911040 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 11910934 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Threonine
at position 272
(I272T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000154092
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000062811]
[ENSMUST00000210112]
[ENSMUST00000226953]
[ENSMUST00000227530]
|
| AlphaFold |
Q8R285 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000062811
AA Change: I272T
PolyPhen 2
Score 0.047 (Sensitivity: 0.94; Specificity: 0.83)
|
| SMART Domains |
Protein: ENSMUSP00000056232
Gene: ENSMUSG00000096735
AA Change: I272T
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
7 |
302 |
4.9e-9 |
PFAM |
|
Pfam:7tm_1
|
27 |
292 |
2.8e-7 |
PFAM |
|
Pfam:V1R
|
34 |
298 |
1.7e-35 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000210112
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000226953
AA Change: I272T
PolyPhen 2
Score 0.047 (Sensitivity: 0.94; Specificity: 0.83)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000227530
AA Change: I272T
PolyPhen 2
Score 0.047 (Sensitivity: 0.94; Specificity: 0.83)
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 24 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adh4 |
A |
G |
3: 138,126,397 (GRCm39) |
I91V |
probably damaging |
Het |
| Ak6 |
T |
C |
13: 100,800,599 (GRCm39) |
V74A |
probably benign |
Het |
| Antxr1 |
C |
A |
6: 87,265,784 (GRCm39) |
V110F |
probably damaging |
Het |
| Anxa1 |
T |
C |
19: 20,355,033 (GRCm39) |
D247G |
probably benign |
Het |
| Dgkg |
T |
C |
16: 22,298,112 (GRCm39) |
|
probably benign |
Het |
| Eva1b |
T |
C |
4: 126,043,443 (GRCm39) |
M161T |
probably benign |
Het |
| Fbxw22 |
C |
A |
9: 109,213,108 (GRCm39) |
V280F |
possibly damaging |
Het |
| Klhl9 |
A |
G |
4: 88,639,378 (GRCm39) |
S288P |
probably damaging |
Het |
| Masp2 |
C |
T |
4: 148,687,186 (GRCm39) |
P23S |
probably benign |
Het |
| Ncam1 |
T |
A |
9: 49,434,865 (GRCm39) |
D600V |
probably damaging |
Het |
| Pcnx4 |
A |
G |
12: 72,626,139 (GRCm39) |
N1115S |
probably damaging |
Het |
| Pdia2 |
A |
G |
17: 26,417,090 (GRCm39) |
V109A |
probably damaging |
Het |
| Pla1a |
G |
T |
16: 38,235,212 (GRCm39) |
H161N |
probably damaging |
Het |
| Prokr2 |
A |
T |
2: 132,223,424 (GRCm39) |
D39E |
probably benign |
Het |
| Sall4 |
T |
C |
2: 168,597,883 (GRCm39) |
D319G |
probably damaging |
Het |
| Sgms2 |
A |
G |
3: 131,135,482 (GRCm39) |
S131P |
possibly damaging |
Het |
| Slc22a2 |
A |
T |
17: 12,827,305 (GRCm39) |
Q319L |
possibly damaging |
Het |
| Slc27a5 |
A |
G |
7: 12,722,566 (GRCm39) |
I636T |
probably benign |
Het |
| Tas2r131 |
T |
G |
6: 132,934,159 (GRCm39) |
T217P |
probably damaging |
Het |
| Trh |
T |
C |
6: 92,219,723 (GRCm39) |
M198V |
possibly damaging |
Het |
| Ube2b |
A |
C |
11: 51,877,546 (GRCm39) |
V141G |
probably damaging |
Het |
| Ube2l6 |
T |
A |
2: 84,639,373 (GRCm39) |
V112E |
probably damaging |
Het |
| Xylb |
C |
T |
9: 119,219,549 (GRCm39) |
Q513* |
probably null |
Het |
| Zbtb4 |
T |
A |
11: 69,667,557 (GRCm39) |
C287* |
probably null |
Het |
|
| Other mutations in Vmn1r79 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01431:Vmn1r79
|
APN |
7 |
11,910,327 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL01953:Vmn1r79
|
APN |
7 |
11,910,382 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4418001:Vmn1r79
|
UTSW |
7 |
11,910,766 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0831:Vmn1r79
|
UTSW |
7 |
11,910,990 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1791:Vmn1r79
|
UTSW |
7 |
11,910,358 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1869:Vmn1r79
|
UTSW |
7 |
11,910,574 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3713:Vmn1r79
|
UTSW |
7 |
11,910,139 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4210:Vmn1r79
|
UTSW |
7 |
11,910,415 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R4243:Vmn1r79
|
UTSW |
7 |
11,910,971 (GRCm39) |
nonsense |
probably null |
|
|
R4244:Vmn1r79
|
UTSW |
7 |
11,910,971 (GRCm39) |
nonsense |
probably null |
|
|
R4839:Vmn1r79
|
UTSW |
7 |
11,910,361 (GRCm39) |
missense |
probably benign |
0.30 |
|
R5677:Vmn1r79
|
UTSW |
7 |
11,910,928 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R6048:Vmn1r79
|
UTSW |
7 |
11,910,448 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7388:Vmn1r79
|
UTSW |
7 |
11,910,668 (GRCm39) |
nonsense |
probably null |
|
|
R7751:Vmn1r79
|
UTSW |
7 |
11,910,762 (GRCm39) |
nonsense |
probably null |
|
|
R8207:Vmn1r79
|
UTSW |
7 |
11,910,415 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R9462:Vmn1r79
|
UTSW |
7 |
11,910,261 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9664:Vmn1r79
|
UTSW |
7 |
11,910,582 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9749:Vmn1r79
|
UTSW |
7 |
11,910,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Posted On |
2012-12-06 |
Incidental Mutation