Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL00743:Vmn2r93'

14799

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r93

Ensembl Gene

ENSMUSG00000079698

Gene Name

vomeronasal 2, receptor 93

Synonyms

EG627132

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.070) question?

Stock #

IGL00743

Quality Score

Status

Chromosome

Chromosomal Location

18298099-18331914 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 18326242 bp

Zygosity

Heterozygous

Amino Acid Change

Phenylalanine to Serine at position 792 (F792S)

Ref Sequence

ENSEMBL: ENSMUSP00000078200 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000079206] [ENSMUST00000231879] [ENSMUST00000231938]

Predicted Effect

probably damaging
Transcript: ENSMUST00000079206
AA Change: F792S

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000078200
Gene: ENSMUSG00000079698
AA Change: F792S

Domain	Start	End	E-Value	Type
signal peptide	1	19	N/A	INTRINSIC
Pfam:ANF_receptor	82	453	5.9e-40	PFAM
Pfam:NCD3G	509	562	2.6e-21	PFAM
Pfam:7tm_3	594	830	1.5e-50	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000231879

Predicted Effect

probably benign
Transcript: ENSMUST00000231938

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 41 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acss1	T	C	2: 150,619,686	E659G	probably benign	Het
Adgrg6	A	C	10: 14,535,959		probably benign	Het
Als2cl	A	G	9: 110,889,159	K323E	possibly damaging	Het
Atm	A	C	9: 53,513,116	S628R	probably benign	Het
Baz2a	T	C	10: 128,114,526	V443A	probably benign	Het
Bclaf3	T	A	X: 159,558,361	F545Y	probably benign	Het
Calcr	T	C	6: 3,717,196	Y88C	probably damaging	Het
Ccdc178	C	T	18: 22,145,444		probably benign	Het
Cdh20	A	G	1: 104,947,428	T312A	probably benign	Het
Chrnd	G	A	1: 87,192,927	W91*	probably null	Het
Cntln	T	C	4: 84,979,415	F413S	probably benign	Het
Ctsq	A	T	13: 61,036,184	I308N	probably damaging	Het
Cyp2d34	A	T	15: 82,617,535	V258D	probably damaging	Het
Dnajc13	G	A	9: 104,162,780	P2044S	probably benign	Het
Hnrnpm	C	A	17: 33,649,902	R517L	probably damaging	Het
Hps6	A	T	19: 46,003,660	D12V	probably damaging	Het
Hpse	T	C	5: 100,698,999	D188G	probably benign	Het
Id2	C	A	12: 25,095,356	E123*	probably null	Het
Ints10	C	T	8: 68,819,333	P562L	probably damaging	Het
Kctd10	G	A	5: 114,367,349	R195C	probably damaging	Het
Kel	A	C	6: 41,688,575	L537R	probably damaging	Het
Kif19a	T	C	11: 114,784,773	V357A	probably damaging	Het
Lrrtm3	A	T	10: 64,089,209	S60T	probably damaging	Het
Myof	C	A	19: 37,960,934	R608L	probably benign	Het
Naa35	A	T	13: 59,630,671	I669F	probably benign	Het
Olfr968	A	G	9: 39,772,111	S230P	possibly damaging	Het
Olfr971	A	T	9: 39,839,706	I91F	probably benign	Het
Pclo	G	T	5: 14,678,021		probably benign	Het
Pik3c3	C	T	18: 30,274,364	S55F	probably damaging	Het
Prdm6	T	G	18: 53,540,228	D153E	possibly damaging	Het
Rnf183	T	C	4: 62,428,373	T63A	probably benign	Het
Samd4b	A	C	7: 28,401,877	I108S	probably damaging	Het
Slc9a7	T	C	X: 20,106,021	D708G	possibly damaging	Het
Stim2	A	G	5: 54,053,493	D90G	probably benign	Het
Tmem52b	A	G	6: 129,516,715	D97G	probably damaging	Het
Tnfsf15	T	C	4: 63,734,281	R98G	probably benign	Het
Uxs1	C	T	1: 43,757,013	V310I	probably benign	Het
Vcan	A	C	13: 89,725,306	M143R	probably damaging	Het
Zfp455	T	C	13: 67,207,898	I345T	probably benign	Het
Zfp938	A	T	10: 82,226,483	M101K	probably benign	Het
Zkscan2	A	G	7: 123,479,972	S921P	probably damaging	Het

Other mutations in Vmn2r93

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01326:Vmn2r93	APN	17	18316644	missense	possibly damaging	0.92
IGL01328:Vmn2r93	APN	17	18325557	missense	probably benign	0.00
IGL01360:Vmn2r93	APN	17	18305248	missense	possibly damaging	0.71
IGL01382:Vmn2r93	APN	17	18313316	nonsense	probably null
IGL01463:Vmn2r93	APN	17	18304888	missense	probably damaging	1.00
IGL02057:Vmn2r93	APN	17	18325770	missense	probably damaging	1.00
IGL02257:Vmn2r93	APN	17	18325508	unclassified	probably benign
IGL02686:Vmn2r93	APN	17	18313264	missense	possibly damaging	0.89
IGL02720:Vmn2r93	APN	17	18305034	missense	probably damaging	1.00
IGL03328:Vmn2r93	APN	17	18304958	missense	probably damaging	1.00
PIT4576001:Vmn2r93	UTSW	17	18313211	missense	probably benign
R0067:Vmn2r93	UTSW	17	18326410	missense	probably benign	0.00
R0067:Vmn2r93	UTSW	17	18326410	missense	probably benign	0.00
R0240:Vmn2r93	UTSW	17	18304799	missense	probably benign	0.00
R0240:Vmn2r93	UTSW	17	18304799	missense	probably benign	0.00
R0488:Vmn2r93	UTSW	17	18326049	missense	probably damaging	1.00
R0667:Vmn2r93	UTSW	17	18326241	missense	probably damaging	1.00
R0668:Vmn2r93	UTSW	17	18298405	missense	probably benign	0.00
R0850:Vmn2r93	UTSW	17	18305017	missense	possibly damaging	0.93
R0924:Vmn2r93	UTSW	17	18304181	missense	probably benign
R0947:Vmn2r93	UTSW	17	18304081	missense	probably benign	0.06
R1124:Vmn2r93	UTSW	17	18298448	missense	probably benign	0.00
R1584:Vmn2r93	UTSW	17	18305151	missense	possibly damaging	0.84
R1943:Vmn2r93	UTSW	17	18325801	missense	probably benign	0.04
R2012:Vmn2r93	UTSW	17	18316578	missense	probably benign	0.01
R2018:Vmn2r93	UTSW	17	18326062	missense	probably damaging	1.00
R2196:Vmn2r93	UTSW	17	18305166	missense	probably damaging	1.00
R2373:Vmn2r93	UTSW	17	18298403	missense	probably benign
R2864:Vmn2r93	UTSW	17	18326061	missense	probably damaging	1.00
R4276:Vmn2r93	UTSW	17	18304830	missense	possibly damaging	0.47
R4446:Vmn2r93	UTSW	17	18304050	missense	possibly damaging	0.93
R4537:Vmn2r93	UTSW	17	18304932	missense	possibly damaging	0.86
R4674:Vmn2r93	UTSW	17	18304993	missense	probably benign	0.34
R4726:Vmn2r93	UTSW	17	18316698	missense	probably damaging	1.00
R4936:Vmn2r93	UTSW	17	18304065	missense	possibly damaging	0.95
R4984:Vmn2r93	UTSW	17	18313127	splice site	probably null
R5111:Vmn2r93	UTSW	17	18326064	missense	probably damaging	0.99
R5749:Vmn2r93	UTSW	17	18298284	missense	probably benign	0.06
R5918:Vmn2r93	UTSW	17	18325768	missense	probably damaging	1.00
R5921:Vmn2r93	UTSW	17	18325768	missense	probably damaging	1.00
R6091:Vmn2r93	UTSW	17	18325696	missense	probably benign	0.06
R6283:Vmn2r93	UTSW	17	18304104	missense	probably benign	0.02
R6680:Vmn2r93	UTSW	17	18316658	nonsense	probably null
R6876:Vmn2r93	UTSW	17	18305188	missense	probably benign	0.00
R6963:Vmn2r93	UTSW	17	18316587	missense	probably damaging	1.00
R6996:Vmn2r93	UTSW	17	18304641	missense	probably damaging	1.00
R7027:Vmn2r93	UTSW	17	18313286	missense	probably benign	0.01
R7034:Vmn2r93	UTSW	17	18326410	missense	probably benign	0.00
R7036:Vmn2r93	UTSW	17	18326410	missense	probably benign	0.00
R7246:Vmn2r93	UTSW	17	18325750	missense	possibly damaging	0.89
R7258:Vmn2r93	UTSW	17	18305141	missense	probably benign	0.32
R7323:Vmn2r93	UTSW	17	18313235	nonsense	probably null
R7325:Vmn2r93	UTSW	17	18303987	missense	probably benign	0.01
R7390:Vmn2r93	UTSW	17	18305067	missense	probably damaging	1.00
R7427:Vmn2r93	UTSW	17	18326410	missense	probably benign	0.00
R7428:Vmn2r93	UTSW	17	18326410	missense	probably benign	0.00
R7448:Vmn2r93	UTSW	17	18325986	missense	probably benign	0.19
R7453:Vmn2r93	UTSW	17	18313318	missense	probably benign	0.10
R7562:Vmn2r93	UTSW	17	18298469	missense	probably benign	0.01
R7662:Vmn2r93	UTSW	17	18305369	missense	probably benign	0.00
R7682:Vmn2r93	UTSW	17	18305321	missense	probably benign	0.03
R7704:Vmn2r93	UTSW	17	18316648	missense	probably benign	0.01
R7772:Vmn2r93	UTSW	17	18313220	missense	probably damaging	0.99
R7957:Vmn2r93	UTSW	17	18325692	nonsense	probably null
R8276:Vmn2r93	UTSW	17	18305387	critical splice donor site	probably null
R8290:Vmn2r93	UTSW	17	18304029	missense	probably damaging	1.00
R8362:Vmn2r93	UTSW	17	18326091	missense	probably benign	0.02
R8376:Vmn2r93	UTSW	17	18304968	missense	probably damaging	1.00
Z1088:Vmn2r93	UTSW	17	18326403	missense	probably damaging	1.00
Z1177:Vmn2r93	UTSW	17	18305338	missense	probably damaging	1.00

Posted On

2012-12-06