Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00480:Zfp772'

14996

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Zfp772

Ensembl Gene

ENSMUSG00000066838

Gene Name

zinc finger protein 772

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.065) question?

Stock #

IGL00480

Quality Score

Status

Chromosome

Chromosomal Location

7205121-7212997 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 7207115 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Serine at position 192 (N192S)

Ref Sequence

ENSEMBL: ENSMUSP00000074055 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000074455]

AlphaFold

Q3UQL6

Predicted Effect

probably benign
Transcript: ENSMUST00000074455
AA Change: N192S

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000074055
Gene: ENSMUSG00000066838
AA Change: N192S

Domain	Start	End	E-Value	Type
KRAB	42	102	1.87e-14	SMART
ZnF_C2H2	193	215	1.36e-2	SMART
ZnF_C2H2	221	243	5.21e-4	SMART
ZnF_C2H2	249	271	1.38e-3	SMART
ZnF_C2H2	277	299	4.24e-4	SMART
ZnF_C2H2	305	327	5.21e-4	SMART
ZnF_C2H2	333	355	2.27e-4	SMART
ZnF_C2H2	361	383	1.18e-2	SMART
ZnF_C2H2	389	411	4.87e-4	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 18 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acvr1c	A	T	2: 58,205,867 (GRCm39)	V31E	probably damaging	Het
Cdc6	T	C	11: 98,799,597 (GRCm39)	V68A	probably benign	Het
Ceacam23	T	A	7: 17,644,622 (GRCm39)	S580T	probably benign	Het
Cfap46	C	T	7: 139,240,605 (GRCm39)	S56N	probably damaging	Het
Gtf3c1	C	T	7: 125,243,430 (GRCm39)	V1821I	probably benign	Het
Haus3	T	C	5: 34,325,272 (GRCm39)	E129G	probably benign	Het
Ogfr	T	C	2: 180,235,355 (GRCm39)		probably benign	Het
Pabpc1l	G	A	2: 163,884,237 (GRCm39)	V325M	probably damaging	Het
Pou6f1	A	G	15: 100,477,928 (GRCm39)		probably benign	Het
Ppp1r9a	A	T	6: 5,158,195 (GRCm39)	D1201V	possibly damaging	Het
Ppp6r2	A	G	15: 89,149,452 (GRCm39)		probably benign	Het
Scn5a	G	T	9: 119,346,604 (GRCm39)	P1016Q	possibly damaging	Het
Selenot	T	A	3: 58,493,503 (GRCm39)		probably benign	Het
Smyd2	C	T	1: 189,632,043 (GRCm39)	R107Q	probably damaging	Het
Tgoln1	T	C	6: 72,593,073 (GRCm39)	K136E	probably benign	Het
Trio	T	C	15: 27,912,829 (GRCm39)		probably benign	Het
Usp24	T	C	4: 106,225,303 (GRCm39)	I645T	probably damaging	Het
Uts2r	T	A	11: 121,051,172 (GRCm39)	M12K	probably benign	Het

Other mutations in Zfp772

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01589:Zfp772	APN	7	7,208,523 (GRCm39)	missense	possibly damaging	0.53
PIT4449001:Zfp772	UTSW	7	7,207,350 (GRCm39)	missense	probably benign	0.03
R1945:Zfp772	UTSW	7	7,206,629 (GRCm39)	missense	probably benign	0.01
R3085:Zfp772	UTSW	7	7,206,699 (GRCm39)	missense	possibly damaging	0.53
R5300:Zfp772	UTSW	7	7,207,157 (GRCm39)	missense	probably benign
R5793:Zfp772	UTSW	7	7,207,283 (GRCm39)	missense	probably benign	0.00
R6252:Zfp772	UTSW	7	7,207,018 (GRCm39)	missense	possibly damaging	0.86
R6605:Zfp772	UTSW	7	7,208,547 (GRCm39)	missense	possibly damaging	0.72
R6751:Zfp772	UTSW	7	7,206,716 (GRCm39)	missense	possibly damaging	0.90
R6812:Zfp772	UTSW	7	7,209,307 (GRCm39)	missense	possibly damaging	0.92
R8171:Zfp772	UTSW	7	7,207,096 (GRCm39)	nonsense	probably null
R8696:Zfp772	UTSW	7	7,208,518 (GRCm39)	missense	possibly damaging	0.53
R9104:Zfp772	UTSW	7	7,207,190 (GRCm39)	missense	possibly damaging	0.53
R9665:Zfp772	UTSW	7	7,212,793 (GRCm39)	start codon destroyed	probably null

Posted On

2012-12-06