Incidental Mutation 'IGL00821:Zfp839'
ID15006
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Zfp839
Ensembl Gene ENSMUSG00000021271
Gene Namezinc finger protein 839
Synonyms2810455K09Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.072) question?
Stock #IGL00821
Quality Score
Status
Chromosome12
Chromosomal Location110850253-110869996 bp(+) (GRCm38)
Type of Mutationcritical splice donor site (2 bp from exon)
DNA Base Change (assembly) T to C at 110865007 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000152386 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000170060] [ENSMUST00000222460]
Predicted Effect probably null
Transcript: ENSMUST00000170060
SMART Domains Protein: ENSMUSP00000131841
Gene: ENSMUSG00000021271

DomainStartEndE-ValueType
low complexity region 271 278 N/A INTRINSIC
ZnF_C2H2 295 320 3.02e0 SMART
low complexity region 377 388 N/A INTRINSIC
Predicted Effect probably null
Transcript: ENSMUST00000222460
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 28 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Cad T C 5: 31,061,484 Y550H probably damaging Het
Cep350 A G 1: 155,862,204 V2631A probably benign Het
Cpa2 A G 6: 30,564,412 D414G probably benign Het
Dhx38 T C 8: 109,555,654 I714V probably benign Het
Dis3 T C 14: 99,091,486 I277V probably benign Het
Espl1 T C 15: 102,299,813 L418P probably damaging Het
F7 A G 8: 13,028,802 T78A probably benign Het
Faim G A 9: 98,992,165 G15R probably damaging Het
Golga3 C A 5: 110,204,933 H897N possibly damaging Het
Itgae T A 11: 73,123,148 D724E probably damaging Het
Klb A T 5: 65,372,149 Y340F probably damaging Het
Kmt2b A T 7: 30,570,613 L2436Q probably damaging Het
Krt17 A G 11: 100,260,631 L112P probably damaging Het
Lrp2 T A 2: 69,459,516 N3660Y probably damaging Het
Mia2 T C 12: 59,170,320 probably null Het
Myh2 C T 11: 67,197,397 probably benign Het
Nr2f1 A G 13: 78,198,114 probably benign Het
Odf2l T A 3: 145,150,987 S568T probably damaging Het
Parl G A 16: 20,298,208 P80S probably damaging Het
Ppfibp2 T G 7: 107,729,876 F531V probably damaging Het
Prpf40b A G 15: 99,316,501 E854G probably benign Het
Rere A G 4: 150,619,463 K1551E probably damaging Het
Sacm1l A T 9: 123,570,549 Q302L possibly damaging Het
Slc41a2 A G 10: 83,313,530 probably benign Het
Smchd1 T C 17: 71,398,623 T994A possibly damaging Het
Ubxn7 G A 16: 32,369,398 D125N probably damaging Het
Zfp667 A G 7: 6,305,397 N355D possibly damaging Het
Zfpm2 T A 15: 41,103,387 N957K probably damaging Het
Other mutations in Zfp839
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00941:Zfp839 APN 12 110860948 missense probably damaging 1.00
R0013:Zfp839 UTSW 12 110868386 missense possibly damaging 0.66
R0013:Zfp839 UTSW 12 110868386 missense possibly damaging 0.66
R0109:Zfp839 UTSW 12 110860874 missense possibly damaging 0.92
R0116:Zfp839 UTSW 12 110858769 intron probably benign
R1219:Zfp839 UTSW 12 110868273 missense possibly damaging 0.63
R1406:Zfp839 UTSW 12 110866310 missense probably damaging 0.99
R1406:Zfp839 UTSW 12 110866310 missense probably damaging 0.99
R1434:Zfp839 UTSW 12 110860899 missense probably benign 0.08
R1653:Zfp839 UTSW 12 110855250 missense probably benign 0.02
R1754:Zfp839 UTSW 12 110855457 missense probably damaging 0.98
R2182:Zfp839 UTSW 12 110868338 missense probably damaging 1.00
R3765:Zfp839 UTSW 12 110855163 missense probably benign 0.22
R3981:Zfp839 UTSW 12 110866331 missense probably damaging 0.97
R4756:Zfp839 UTSW 12 110855201 missense possibly damaging 0.92
R5088:Zfp839 UTSW 12 110868176 missense probably damaging 0.99
R5394:Zfp839 UTSW 12 110855586 missense probably benign 0.05
R5619:Zfp839 UTSW 12 110864036 missense probably damaging 1.00
R6856:Zfp839 UTSW 12 110866761 nonsense probably null
R7661:Zfp839 UTSW 12 110868792 missense probably benign 0.32
R7860:Zfp839 UTSW 12 110855626 missense probably damaging 1.00
R7943:Zfp839 UTSW 12 110855626 missense probably damaging 1.00
R8022:Zfp839 UTSW 12 110855098 missense probably damaging 1.00
Z1177:Zfp839 UTSW 12 110866784 missense probably benign 0.03
Posted On2012-12-06