Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL00743:Zfp938'

15013

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Zfp938

Ensembl Gene

ENSMUSG00000062931

Gene Name

zinc finger protein 938

Synonyms

B230315N10Rik

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.114) question?

Stock #

IGL00743

Quality Score

Status

Chromosome

Chromosomal Location

82224850-82241280 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 82226483 bp

Zygosity

Heterozygous

Amino Acid Change

Methionine to Lysine at position 101 (M101K)

Ref Sequence

ENSEMBL: ENSMUSP00000047110 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000041264] [ENSMUST00000156218]

Predicted Effect

probably benign
Transcript: ENSMUST00000041264
AA Change: M101K

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000047110
Gene: ENSMUSG00000062931
AA Change: M101K

Domain	Start	End	E-Value	Type
KRAB	4	64	5.28e-14	SMART
ZnF_C2H2	161	188	2.82e1	SMART
ZnF_C2H2	267	289	1.23e0	SMART
ZnF_C2H2	295	317	2.91e-2	SMART
ZnF_C2H2	323	345	2.4e-3	SMART
ZnF_C2H2	351	373	7.26e-3	SMART
ZnF_C2H2	379	401	4.65e-1	SMART
ZnF_C2H2	407	429	1.47e-3	SMART
ZnF_C2H2	435	457	5.59e-4	SMART
ZnF_C2H2	463	485	1.82e-3	SMART
ZnF_C2H2	491	513	3.63e-3	SMART
ZnF_C2H2	519	541	7.67e-2	SMART
ZnF_C2H2	547	569	2.4e-3	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000156218

SMART Domains

Protein: ENSMUSP00000121613
Gene: ENSMUSG00000062931

Domain	Start	End	E-Value	Type
KRAB	4	64	5.28e-14	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 41 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acss1	T	C	2: 150,619,686	E659G	probably benign	Het
Adgrg6	A	C	10: 14,535,959		probably benign	Het
Als2cl	A	G	9: 110,889,159	K323E	possibly damaging	Het
Atm	A	C	9: 53,513,116	S628R	probably benign	Het
Baz2a	T	C	10: 128,114,526	V443A	probably benign	Het
Bclaf3	T	A	X: 159,558,361	F545Y	probably benign	Het
Calcr	T	C	6: 3,717,196	Y88C	probably damaging	Het
Ccdc178	C	T	18: 22,145,444		probably benign	Het
Cdh20	A	G	1: 104,947,428	T312A	probably benign	Het
Chrnd	G	A	1: 87,192,927	W91*	probably null	Het
Cntln	T	C	4: 84,979,415	F413S	probably benign	Het
Ctsq	A	T	13: 61,036,184	I308N	probably damaging	Het
Cyp2d34	A	T	15: 82,617,535	V258D	probably damaging	Het
Dnajc13	G	A	9: 104,162,780	P2044S	probably benign	Het
Hnrnpm	C	A	17: 33,649,902	R517L	probably damaging	Het
Hps6	A	T	19: 46,003,660	D12V	probably damaging	Het
Hpse	T	C	5: 100,698,999	D188G	probably benign	Het
Id2	C	A	12: 25,095,356	E123*	probably null	Het
Ints10	C	T	8: 68,819,333	P562L	probably damaging	Het
Kctd10	G	A	5: 114,367,349	R195C	probably damaging	Het
Kel	A	C	6: 41,688,575	L537R	probably damaging	Het
Kif19a	T	C	11: 114,784,773	V357A	probably damaging	Het
Lrrtm3	A	T	10: 64,089,209	S60T	probably damaging	Het
Myof	C	A	19: 37,960,934	R608L	probably benign	Het
Naa35	A	T	13: 59,630,671	I669F	probably benign	Het
Olfr968	A	G	9: 39,772,111	S230P	possibly damaging	Het
Olfr971	A	T	9: 39,839,706	I91F	probably benign	Het
Pclo	G	T	5: 14,678,021		probably benign	Het
Pik3c3	C	T	18: 30,274,364	S55F	probably damaging	Het
Prdm6	T	G	18: 53,540,228	D153E	possibly damaging	Het
Rnf183	T	C	4: 62,428,373	T63A	probably benign	Het
Samd4b	A	C	7: 28,401,877	I108S	probably damaging	Het
Slc9a7	T	C	X: 20,106,021	D708G	possibly damaging	Het
Stim2	A	G	5: 54,053,493	D90G	probably benign	Het
Tmem52b	A	G	6: 129,516,715	D97G	probably damaging	Het
Tnfsf15	T	C	4: 63,734,281	R98G	probably benign	Het
Uxs1	C	T	1: 43,757,013	V310I	probably benign	Het
Vcan	A	C	13: 89,725,306	M143R	probably damaging	Het
Vmn2r93	T	C	17: 18,326,242	F792S	probably damaging	Het
Zfp455	T	C	13: 67,207,898	I345T	probably benign	Het
Zkscan2	A	G	7: 123,479,972	S921P	probably damaging	Het

Other mutations in Zfp938

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00659:Zfp938	APN	10	82227521	utr 3 prime	probably benign
IGL01764:Zfp938	APN	10	82227790	splice site	probably benign
IGL01814:Zfp938	APN	10	82226218	missense	probably benign
IGL02244:Zfp938	APN	10	82226072	missense	possibly damaging	0.86
IGL02865:Zfp938	APN	10	82226192	missense	probably benign	0.33
R0372:Zfp938	UTSW	10	82227828	missense	probably damaging	1.00
R0666:Zfp938	UTSW	10	82225772	missense	probably damaging	1.00
R0964:Zfp938	UTSW	10	82225419	missense	probably benign	0.00
R1453:Zfp938	UTSW	10	82227798	critical splice donor site	probably null
R1672:Zfp938	UTSW	10	82225148	missense	probably benign
R1929:Zfp938	UTSW	10	82225547	missense	probably damaging	1.00
R1959:Zfp938	UTSW	10	82225631	missense	probably damaging	1.00
R2127:Zfp938	UTSW	10	82226042	missense	probably benign
R2271:Zfp938	UTSW	10	82225547	missense	probably damaging	1.00
R2900:Zfp938	UTSW	10	82225506	missense	possibly damaging	0.92
R4502:Zfp938	UTSW	10	82226271	missense	possibly damaging	0.73
R4503:Zfp938	UTSW	10	82226271	missense	possibly damaging	0.73
R4886:Zfp938	UTSW	10	82226123	missense	probably benign	0.33
R4934:Zfp938	UTSW	10	82226178	missense	possibly damaging	0.86
R5174:Zfp938	UTSW	10	82226004	missense	possibly damaging	0.53
R5410:Zfp938	UTSW	10	82225258	missense	possibly damaging	0.89
R6284:Zfp938	UTSW	10	82227566	missense	possibly damaging	0.73
R6491:Zfp938	UTSW	10	82227529	makesense	probably null
R6575:Zfp938	UTSW	10	82225326	nonsense	probably null
R6649:Zfp938	UTSW	10	82225398	missense	probably damaging	0.99
R7992:Zfp938	UTSW	10	82225943	missense	possibly damaging	0.53
R8211:Zfp938	UTSW	10	82226585	missense	possibly damaging	0.53
R8313:Zfp938	UTSW	10	82225588	missense	possibly damaging	0.75
X0066:Zfp938	UTSW	10	82226097	missense	probably benign	0.33

Posted On

2012-12-06