Incidental Mutation 'IGL00659:Zfp938'
| ID |
15014 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Zfp938
|
| Ensembl Gene |
ENSMUSG00000062931 |
| Gene Name |
zinc finger protein 938 |
| Synonyms |
B230315N10Rik |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.074)
|
| Stock # |
IGL00659
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
10 |
| Chromosomal Location |
82060684-82077114 bp(-) (GRCm39) |
| Type of Mutation |
utr 3 prime |
| DNA Base Change (assembly) |
T to A
at 82063355 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000121613
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041264]
[ENSMUST00000156218]
|
| AlphaFold |
E9Q9G3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000041264
|
| SMART Domains |
Protein: ENSMUSP00000047110
Gene: ENSMUSG00000062931
| Domain | Start | End | E-Value | Type |
|---|
|
KRAB
|
4 |
64 |
5.28e-14 |
SMART |
|
ZnF_C2H2
|
161 |
188 |
2.82e1 |
SMART |
|
ZnF_C2H2
|
267 |
289 |
1.23e0 |
SMART |
|
ZnF_C2H2
|
295 |
317 |
2.91e-2 |
SMART |
|
ZnF_C2H2
|
323 |
345 |
2.4e-3 |
SMART |
|
ZnF_C2H2
|
351 |
373 |
7.26e-3 |
SMART |
|
ZnF_C2H2
|
379 |
401 |
4.65e-1 |
SMART |
|
ZnF_C2H2
|
407 |
429 |
1.47e-3 |
SMART |
|
ZnF_C2H2
|
435 |
457 |
5.59e-4 |
SMART |
|
ZnF_C2H2
|
463 |
485 |
1.82e-3 |
SMART |
|
ZnF_C2H2
|
491 |
513 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
519 |
541 |
7.67e-2 |
SMART |
|
ZnF_C2H2
|
547 |
569 |
2.4e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000156218
|
| SMART Domains |
Protein: ENSMUSP00000121613
Gene: ENSMUSG00000062931
| Domain | Start | End | E-Value | Type |
|---|
|
KRAB
|
4 |
64 |
5.28e-14 |
SMART |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 22 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ap4e1 |
T |
C |
2: 126,905,221 (GRCm39) |
V964A |
probably benign |
Het |
| Birc6 |
T |
A |
17: 74,967,648 (GRCm39) |
V4197E |
probably damaging |
Het |
| C8b |
T |
A |
4: 104,658,531 (GRCm39) |
|
probably benign |
Het |
| Cdh13 |
A |
G |
8: 120,039,406 (GRCm39) |
D616G |
probably damaging |
Het |
| Cfi |
A |
G |
3: 129,630,462 (GRCm39) |
K2E |
unknown |
Het |
| Chek1 |
C |
A |
9: 36,633,895 (GRCm39) |
|
probably null |
Het |
| Chst11 |
T |
G |
10: 83,027,639 (GRCm39) |
|
probably benign |
Het |
| Dhx29 |
A |
G |
13: 113,103,169 (GRCm39) |
|
probably benign |
Het |
| Erbb3 |
A |
G |
10: 128,406,852 (GRCm39) |
S1049P |
probably damaging |
Het |
| Fkbp15 |
T |
C |
4: 62,251,917 (GRCm39) |
|
probably benign |
Het |
| Fxr2 |
C |
A |
11: 69,531,076 (GRCm39) |
Q51K |
probably benign |
Het |
| Kpna7 |
T |
A |
5: 144,944,056 (GRCm39) |
I50F |
probably damaging |
Het |
| Mdm2 |
T |
C |
10: 117,538,204 (GRCm39) |
R65G |
possibly damaging |
Het |
| N4bp1 |
G |
T |
8: 87,588,430 (GRCm39) |
D169E |
probably damaging |
Het |
| Nlrp9a |
A |
G |
7: 26,257,050 (GRCm39) |
I134V |
probably benign |
Het |
| Plrg1 |
T |
A |
3: 82,977,980 (GRCm39) |
S400T |
probably damaging |
Het |
| Polr1b |
T |
C |
2: 128,960,020 (GRCm39) |
|
probably null |
Het |
| Sec23b |
T |
C |
2: 144,425,690 (GRCm39) |
|
probably null |
Het |
| Ubr4 |
C |
T |
4: 139,148,556 (GRCm39) |
T1680I |
probably damaging |
Het |
| Usp29 |
A |
G |
7: 6,965,281 (GRCm39) |
N375D |
probably benign |
Het |
| Wrn |
A |
G |
8: 33,812,405 (GRCm39) |
|
probably benign |
Het |
| Zfp422 |
G |
A |
6: 116,603,466 (GRCm39) |
Q178* |
probably null |
Het |
|
| Other mutations in Zfp938 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00743:Zfp938
|
APN |
10 |
82,062,317 (GRCm39) |
missense |
probably benign |
|
|
IGL01764:Zfp938
|
APN |
10 |
82,063,624 (GRCm39) |
splice site |
probably benign |
|
|
IGL01814:Zfp938
|
APN |
10 |
82,062,052 (GRCm39) |
missense |
probably benign |
|
|
IGL02244:Zfp938
|
APN |
10 |
82,061,906 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL02865:Zfp938
|
APN |
10 |
82,062,026 (GRCm39) |
missense |
probably benign |
0.33 |
|
R0372:Zfp938
|
UTSW |
10 |
82,063,662 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0666:Zfp938
|
UTSW |
10 |
82,061,606 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0964:Zfp938
|
UTSW |
10 |
82,061,253 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1453:Zfp938
|
UTSW |
10 |
82,063,632 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1672:Zfp938
|
UTSW |
10 |
82,060,982 (GRCm39) |
missense |
probably benign |
|
|
R1929:Zfp938
|
UTSW |
10 |
82,061,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1959:Zfp938
|
UTSW |
10 |
82,061,465 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2127:Zfp938
|
UTSW |
10 |
82,061,876 (GRCm39) |
missense |
probably benign |
|
|
R2271:Zfp938
|
UTSW |
10 |
82,061,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2900:Zfp938
|
UTSW |
10 |
82,061,340 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4502:Zfp938
|
UTSW |
10 |
82,062,105 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R4503:Zfp938
|
UTSW |
10 |
82,062,105 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R4886:Zfp938
|
UTSW |
10 |
82,061,957 (GRCm39) |
missense |
probably benign |
0.33 |
|
R4934:Zfp938
|
UTSW |
10 |
82,062,012 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5174:Zfp938
|
UTSW |
10 |
82,061,838 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5410:Zfp938
|
UTSW |
10 |
82,061,092 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6284:Zfp938
|
UTSW |
10 |
82,063,400 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R6491:Zfp938
|
UTSW |
10 |
82,063,363 (GRCm39) |
makesense |
probably null |
|
|
R6575:Zfp938
|
UTSW |
10 |
82,061,160 (GRCm39) |
nonsense |
probably null |
|
|
R6649:Zfp938
|
UTSW |
10 |
82,061,232 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7992:Zfp938
|
UTSW |
10 |
82,061,777 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8211:Zfp938
|
UTSW |
10 |
82,062,419 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8313:Zfp938
|
UTSW |
10 |
82,061,422 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R8963:Zfp938
|
UTSW |
10 |
82,061,287 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
X0066:Zfp938
|
UTSW |
10 |
82,061,931 (GRCm39) |
missense |
probably benign |
0.33 |
|
| Posted On |
2012-12-06 |
Incidental Mutation