Incidental Mutation 'IGL00754:Zfp945'
ID 15015
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Zfp945
Ensembl Gene ENSMUSG00000059142
Gene Name zinc finger protein 945
Synonyms C730040L01Rik, A630033E08Rik
Accession Numbers
Essential gene? Probably non essential (E-score: 0.063) question?
Stock # IGL00754
Quality Score
Status
Chromosome 17
Chromosomal Location 23065671-23086108 bp(-) (GRCm39)
Type of Mutation unclassified
DNA Base Change (assembly) T to C at 23070931 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000117978 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000088696] [ENSMUST00000150092] [ENSMUST00000160457]
AlphaFold F6WAU7
Predicted Effect unknown
Transcript: ENSMUST00000088696
AA Change: R323G
SMART Domains Protein: ENSMUSP00000086074
Gene: ENSMUSG00000059142
AA Change: R323G

DomainStartEndE-ValueType
KRAB 13 68 9.12e-18 SMART
ZnF_C2H2 210 232 1.45e-2 SMART
ZnF_C2H2 238 260 1.03e-2 SMART
ZnF_C2H2 266 288 1.76e-1 SMART
ZnF_C2H2 322 344 7.37e-4 SMART
ZnF_C2H2 350 372 1.5e-4 SMART
ZnF_C2H2 378 400 5.14e-3 SMART
ZnF_C2H2 406 428 9.73e-4 SMART
ZnF_C2H2 434 456 2.99e-4 SMART
ZnF_C2H2 462 484 4.54e-4 SMART
ZnF_C2H2 490 512 2.4e-3 SMART
ZnF_C2H2 518 540 1.38e-3 SMART
ZnF_C2H2 546 568 1.13e-4 SMART
ZnF_C2H2 574 596 5.59e-4 SMART
ZnF_C2H2 602 624 9.31e1 SMART
ZnF_C2H2 630 652 7.9e-4 SMART
ZnF_C2H2 658 680 3.69e-4 SMART
ZnF_C2H2 686 708 3.16e-3 SMART
ZnF_C2H2 714 736 2.95e-3 SMART
ZnF_C2H2 742 764 1.98e-4 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000095615
Predicted Effect probably benign
Transcript: ENSMUST00000150092
SMART Domains Protein: ENSMUSP00000117978
Gene: ENSMUSG00000059142

DomainStartEndE-ValueType
KRAB 34 89 9.12e-18 SMART
Predicted Effect unknown
Transcript: ENSMUST00000160457
AA Change: R344G
SMART Domains Protein: ENSMUSP00000124123
Gene: ENSMUSG00000059142
AA Change: R344G

DomainStartEndE-ValueType
KRAB 34 89 9.12e-18 SMART
ZnF_C2H2 231 253 1.45e-2 SMART
ZnF_C2H2 259 281 1.03e-2 SMART
ZnF_C2H2 287 309 1.76e-1 SMART
ZnF_C2H2 343 365 7.37e-4 SMART
ZnF_C2H2 371 393 1.5e-4 SMART
ZnF_C2H2 399 421 5.14e-3 SMART
ZnF_C2H2 427 449 9.73e-4 SMART
ZnF_C2H2 455 477 2.99e-4 SMART
ZnF_C2H2 483 505 4.54e-4 SMART
ZnF_C2H2 511 533 2.4e-3 SMART
ZnF_C2H2 539 561 1.38e-3 SMART
ZnF_C2H2 567 589 1.13e-4 SMART
ZnF_C2H2 595 617 5.59e-4 SMART
ZnF_C2H2 623 645 9.31e1 SMART
ZnF_C2H2 651 673 7.9e-4 SMART
ZnF_C2H2 679 701 3.69e-4 SMART
ZnF_C2H2 707 729 3.16e-3 SMART
ZnF_C2H2 735 757 2.95e-3 SMART
ZnF_C2H2 763 785 1.98e-4 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 29 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ahi1 G A 10: 20,848,040 (GRCm39) G483R probably damaging Het
Ano1 T C 7: 144,150,968 (GRCm39) I816V probably damaging Het
Aprt T C 8: 123,302,232 (GRCm39) Q77R probably benign Het
Bcas3 T A 11: 85,386,649 (GRCm39) probably benign Het
Casp8ap2 A G 4: 32,641,036 (GRCm39) M697V probably benign Het
Cgas G A 9: 78,342,770 (GRCm39) P344L probably damaging Het
Chrnd A C 1: 87,123,506 (GRCm39) E348A probably benign Het
Ctnnbl1 A T 2: 157,661,461 (GRCm39) S324C possibly damaging Het
Dgkb C A 12: 38,488,567 (GRCm39) N644K probably benign Het
Dnajc13 A T 9: 104,051,697 (GRCm39) L1720* probably null Het
Ehbp1 A G 11: 22,197,967 (GRCm39) probably benign Het
Eif1b G T 9: 120,323,686 (GRCm39) C94F probably benign Het
Fmnl3 G A 15: 99,220,551 (GRCm39) T577I probably damaging Het
Gm28042 G A 2: 119,860,837 (GRCm39) G96R probably damaging Het
Hcrtr1 A G 4: 130,031,026 (GRCm39) V86A probably damaging Het
Klrc3 A T 6: 129,618,389 (GRCm39) S131R probably damaging Het
Mboat4 A G 8: 34,591,708 (GRCm39) T382A probably benign Het
Oosp1 A T 19: 11,645,069 (GRCm39) H198Q possibly damaging Het
Parp14 T C 16: 35,659,741 (GRCm39) D1627G probably benign Het
Pdcd11 T A 19: 47,092,221 (GRCm39) F406I possibly damaging Het
Ppara T C 15: 85,661,843 (GRCm39) L28S probably damaging Het
Samd3 A G 10: 26,120,425 (GRCm39) T140A probably benign Het
Sf3b1 A G 1: 55,026,645 (GRCm39) F1255L probably damaging Het
Stard6 T A 18: 70,616,559 (GRCm39) S73T probably benign Het
Tnip2 T C 5: 34,656,643 (GRCm39) I221V probably benign Het
Ttn A G 2: 76,612,429 (GRCm39) I8859T possibly damaging Het
Ube3b T C 5: 114,553,348 (GRCm39) S907P possibly damaging Het
Utp25 G T 1: 192,797,309 (GRCm39) N514K probably damaging Het
Utrn A G 10: 12,539,236 (GRCm39) V1927A probably benign Het
Other mutations in Zfp945
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01077:Zfp945 APN 17 23,071,359 (GRCm39) missense probably damaging 0.99
IGL02706:Zfp945 APN 17 23,076,256 (GRCm39) missense probably damaging 1.00
IGL03408:Zfp945 APN 17 23,071,511 (GRCm39) nonsense probably null
Small-scale UTSW 17 23,069,955 (GRCm39) missense probably damaging 1.00
R0427:Zfp945 UTSW 17 23,084,226 (GRCm39) missense probably benign 0.10
R0718:Zfp945 UTSW 17 23,070,004 (GRCm39) missense probably damaging 1.00
R1305:Zfp945 UTSW 17 23,071,360 (GRCm39) missense probably damaging 0.97
R1801:Zfp945 UTSW 17 23,070,736 (GRCm39) missense probably damaging 0.97
R1837:Zfp945 UTSW 17 23,070,247 (GRCm39) missense probably damaging 1.00
R2001:Zfp945 UTSW 17 23,076,223 (GRCm39) critical splice donor site probably null
R4193:Zfp945 UTSW 17 23,070,144 (GRCm39) unclassified probably benign
R4247:Zfp945 UTSW 17 23,069,583 (GRCm39) missense probably damaging 0.98
R5026:Zfp945 UTSW 17 23,069,859 (GRCm39) missense probably damaging 1.00
R5918:Zfp945 UTSW 17 23,069,955 (GRCm39) missense probably damaging 1.00
R6076:Zfp945 UTSW 17 23,070,432 (GRCm39) missense probably damaging 1.00
R6664:Zfp945 UTSW 17 23,071,339 (GRCm39) missense probably damaging 0.99
R6997:Zfp945 UTSW 17 23,071,543 (GRCm39) nonsense probably null
R7040:Zfp945 UTSW 17 23,071,264 (GRCm39) missense probably damaging 0.98
R7479:Zfp945 UTSW 17 23,070,340 (GRCm39) missense possibly damaging 0.93
R7566:Zfp945 UTSW 17 23,070,727 (GRCm39) missense possibly damaging 0.71
R7948:Zfp945 UTSW 17 23,071,096 (GRCm39) missense unknown
R8383:Zfp945 UTSW 17 23,070,798 (GRCm39) missense probably benign 0.05
R9776:Zfp945 UTSW 17 23,070,582 (GRCm39) missense possibly damaging 0.93
R9790:Zfp945 UTSW 17 23,071,228 (GRCm39) missense probably benign 0.33
R9791:Zfp945 UTSW 17 23,071,228 (GRCm39) missense probably benign 0.33
X0063:Zfp945 UTSW 17 23,071,202 (GRCm39) unclassified probably benign
Posted On 2012-12-06