Mutagenetix > Incidental Mutations

Incidental Mutation 'R1288:Vmn1r234'

150683

Institutional Source

Beutler Lab

Gene Symbol

Vmn1r234

Ensembl Gene

ENSMUSG00000057203

Gene Name

vomeronasal 1 receptor 234

Synonyms

V1rf1

MMRRC Submission

039354-MU

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.056) question?

Stock #

R1288 (G1)

Quality Score

217

Status

Not validated

Chromosome

Chromosomal Location

21228826-21229815 bp(+) (GRCm38)

Type of Mutation

frame shift

DNA Base Change (assembly)

CTT to CTTT at 21229251 bp

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000078579 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000079633]

Predicted Effect

probably null
Transcript: ENSMUST00000079633

SMART Domains

Protein: ENSMUSP00000078579
Gene: ENSMUSG00000057203

Domain	Start	End	E-Value	Type
Pfam:TAS2R	25	315	2.8e-14	PFAM
Pfam:V1R	57	318	2.3e-26	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000177028

Coding Region Coverage

1x: 98.9%
3x: 98.1%
10x: 95.6%
20x: 90.1%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 23 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adgrd1	A	T	5: 129,129,007	D247V	probably damaging	Het
Ano5	A	T	7: 51,546,872	S184C	probably damaging	Het
Anpep	C	T	7: 79,838,256	E518K	probably benign	Het
Atxn3	C	T	12: 101,942,178		probably null	Het
BC005537	A	T	13: 24,804,900	E54V	probably damaging	Het
Ccdc150	A	T	1: 54,364,458	E881V	probably damaging	Het
Cep126	A	T	9: 8,112,181	N130K	probably benign	Het
Enoph1	A	G	5: 100,040,279	T21A	possibly damaging	Het
Fbxw28	A	G	9: 109,337,293	I165T	probably damaging	Het
Lrp12	A	T	15: 39,878,403	N305K	probably damaging	Het
Msl2	A	G	9: 101,102,109	T561A	probably benign	Het
Mup21	G	T	4: 62,150,697	A19E	probably benign	Het
Myh13	T	C	11: 67,353,718	I1027T	probably benign	Het
Nkg7	A	G	7: 43,437,662		probably null	Het
Nme8	A	G	13: 19,674,449	V73A	possibly damaging	Het
Olfr1135	G	A	2: 87,671,572	A265V	probably benign	Het
Olfr123	T	A	17: 37,795,693	L83Q	probably damaging	Het
Olfr138	A	G	17: 38,275,223	T151A	probably benign	Het
Olfr68	A	T	7: 103,778,042	L101Q	possibly damaging	Het
Olfr822	A	G	10: 130,075,285	N292D	probably damaging	Het
Rapgef3	C	A	15: 97,759,342	S267I	probably benign	Het
Trhde	T	A	10: 114,801,290	D4V	probably benign	Het
Zfp40	T	A	17: 23,182,162	I36L	probably benign	Het

Other mutations in Vmn1r234

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00089:Vmn1r234	APN	17	21229598	missense	possibly damaging	0.95
IGL01485:Vmn1r234	APN	17	21228909	missense	possibly damaging	0.53
IGL02149:Vmn1r234	APN	17	21229007	missense	probably benign	0.00
IGL02291:Vmn1r234	APN	17	21228931	missense	probably benign	0.28
IGL02993:Vmn1r234	APN	17	21229703	missense	probably damaging	0.99
IGL03223:Vmn1r234	APN	17	21229391	missense	probably damaging	0.98
R0626:Vmn1r234	UTSW	17	21229745	missense	probably benign	0.17
R1274:Vmn1r234	UTSW	17	21229251	frame shift	probably null
R1275:Vmn1r234	UTSW	17	21229251	frame shift	probably null
R1289:Vmn1r234	UTSW	17	21229251	frame shift	probably null
R1319:Vmn1r234	UTSW	17	21228910	missense	probably benign	0.01
R1412:Vmn1r234	UTSW	17	21229250	missense	probably benign	0.01
R2323:Vmn1r234	UTSW	17	21229703	missense	probably benign	0.10
R3755:Vmn1r234	UTSW	17	21229009	missense	probably damaging	0.98
R4299:Vmn1r234	UTSW	17	21229021	missense	probably benign	0.03
R5301:Vmn1r234	UTSW	17	21229327	missense	probably benign	0.11
R5741:Vmn1r234	UTSW	17	21229469	missense	probably benign	0.21
R6197:Vmn1r234	UTSW	17	21229327	missense	probably benign	0.04
R6218:Vmn1r234	UTSW	17	21229721	missense	possibly damaging	0.71
R6486:Vmn1r234	UTSW	17	21229342	missense	probably benign	0.11
R7482:Vmn1r234	UTSW	17	21229375	missense	probably benign	0.07
R7635:Vmn1r234	UTSW	17	21229217	missense	probably damaging	1.00
R8295:Vmn1r234	UTSW	17	21228839	missense	probably benign	0.01
X0028:Vmn1r234	UTSW	17	21228890	missense	probably benign	0.17

Predicted Primers

PCR Primer
(F):5'- GTGTTCCACAAGCAATGGCAGC -3'
(R):5'- CTGTGCCTGTGCAAAATGAGAACC -3'

Sequencing Primer
(F):5'- CACAAGCAATGGCAGCTTTTG -3'
(R):5'- ACATTGCACAATTTTGCAGACA -3'

Posted On

2014-01-29