Incidental Mutation 'R1289:Vmn1r234'
| ID |
150746 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Vmn1r234
|
| Ensembl Gene |
ENSMUSG00000057203 |
| Gene Name |
vomeronasal 1 receptor 234 |
| Synonyms |
V1rf1 |
| MMRRC Submission |
039355-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.050)
|
| Stock # |
R1289 (G1)
|
| Quality Score |
217 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
21449088-21450078 bp(+) (GRCm39) |
| Type of Mutation |
frame shift |
| DNA Base Change (assembly) |
CTT to CTTT
at 21449513 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000078579
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000079633]
|
| AlphaFold |
Q8R298 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000079633
|
| SMART Domains |
Protein: ENSMUSP00000078579
Gene: ENSMUSG00000057203
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
25 |
315 |
2.8e-14 |
PFAM |
|
Pfam:V1R
|
57 |
318 |
2.3e-26 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000177028
|
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.2%
- 10x: 96.1%
- 20x: 92.1%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 22 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930522L14Rik |
A |
T |
5: 109,884,756 (GRCm39) |
Y367* |
probably null |
Het |
| Anpep |
C |
T |
7: 79,488,004 (GRCm39) |
E518K |
probably benign |
Het |
| Arap3 |
T |
C |
18: 38,115,026 (GRCm39) |
R997G |
possibly damaging |
Het |
| Brd10 |
T |
C |
19: 29,700,852 (GRCm39) |
I745M |
probably benign |
Het |
| Col22a1 |
T |
G |
15: 71,709,226 (GRCm39) |
K655T |
unknown |
Het |
| Dync1h1 |
G |
A |
12: 110,602,943 (GRCm39) |
E2195K |
probably benign |
Het |
| Glcci1 |
G |
A |
6: 8,593,088 (GRCm39) |
V298I |
possibly damaging |
Het |
| Gm14401 |
T |
C |
2: 176,778,789 (GRCm39) |
Y292H |
possibly damaging |
Het |
| Gm9956 |
T |
A |
10: 56,621,676 (GRCm39) |
S113T |
probably damaging |
Het |
| Gpr75 |
T |
C |
11: 30,842,706 (GRCm39) |
I537T |
probably benign |
Het |
| Hars2 |
T |
G |
18: 36,916,465 (GRCm39) |
|
probably null |
Het |
| Helq |
A |
G |
5: 100,944,330 (GRCm39) |
V260A |
probably damaging |
Het |
| Ift172 |
A |
C |
5: 31,438,320 (GRCm39) |
F46V |
probably damaging |
Het |
| Klk1b9 |
A |
T |
7: 43,627,848 (GRCm39) |
I49L |
probably benign |
Het |
| Lrrk2 |
T |
G |
15: 91,696,563 (GRCm39) |
N2450K |
probably benign |
Het |
| Mtor |
T |
C |
4: 148,554,764 (GRCm39) |
V867A |
probably benign |
Het |
| Nlgn1 |
G |
T |
3: 25,488,400 (GRCm39) |
T645K |
possibly damaging |
Het |
| Nphs1 |
T |
C |
7: 30,170,603 (GRCm39) |
L931P |
probably damaging |
Het |
| Phf19 |
T |
C |
2: 34,786,042 (GRCm39) |
T476A |
probably benign |
Het |
| Rnf169 |
T |
C |
7: 99,574,943 (GRCm39) |
I551V |
probably benign |
Het |
| Ryr3 |
T |
A |
2: 112,475,630 (GRCm39) |
E4472V |
probably damaging |
Het |
| Tek |
T |
G |
4: 94,693,067 (GRCm39) |
F209V |
probably damaging |
Het |
|
| Other mutations in Vmn1r234 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00089:Vmn1r234
|
APN |
17 |
21,449,860 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01485:Vmn1r234
|
APN |
17 |
21,449,171 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
IGL02149:Vmn1r234
|
APN |
17 |
21,449,269 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02291:Vmn1r234
|
APN |
17 |
21,449,193 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL02993:Vmn1r234
|
APN |
17 |
21,449,965 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03223:Vmn1r234
|
APN |
17 |
21,449,653 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0626:Vmn1r234
|
UTSW |
17 |
21,450,007 (GRCm39) |
missense |
probably benign |
0.17 |
|
R1274:Vmn1r234
|
UTSW |
17 |
21,449,513 (GRCm39) |
frame shift |
probably null |
|
|
R1275:Vmn1r234
|
UTSW |
17 |
21,449,513 (GRCm39) |
frame shift |
probably null |
|
|
R1288:Vmn1r234
|
UTSW |
17 |
21,449,513 (GRCm39) |
frame shift |
probably null |
|
|
R1319:Vmn1r234
|
UTSW |
17 |
21,449,172 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1412:Vmn1r234
|
UTSW |
17 |
21,449,512 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2323:Vmn1r234
|
UTSW |
17 |
21,449,965 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3755:Vmn1r234
|
UTSW |
17 |
21,449,271 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4299:Vmn1r234
|
UTSW |
17 |
21,449,283 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5301:Vmn1r234
|
UTSW |
17 |
21,449,589 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5741:Vmn1r234
|
UTSW |
17 |
21,449,731 (GRCm39) |
missense |
probably benign |
0.21 |
|
R6197:Vmn1r234
|
UTSW |
17 |
21,449,589 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6218:Vmn1r234
|
UTSW |
17 |
21,449,983 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6486:Vmn1r234
|
UTSW |
17 |
21,449,604 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7482:Vmn1r234
|
UTSW |
17 |
21,449,637 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7635:Vmn1r234
|
UTSW |
17 |
21,449,479 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8295:Vmn1r234
|
UTSW |
17 |
21,449,101 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9506:Vmn1r234
|
UTSW |
17 |
21,449,503 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9530:Vmn1r234
|
UTSW |
17 |
21,449,104 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0028:Vmn1r234
|
UTSW |
17 |
21,449,152 (GRCm39) |
missense |
probably benign |
0.17 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTGTTCCACAAGCAATGGCAGC -3'
(R):5'- CTGTGCCTGTGCAAAATGAGAACC -3'
Sequencing Primer
(F):5'- CACAAGCAATGGCAGCTTTTG -3'
(R):5'- ACATTGCACAATTTTGCAGACA -3'
|
| Posted On |
2014-01-29 |
Incidental Mutation