Incidental Mutation 'R1292:Vdac3-ps1'
ID150823
Institutional Source Beutler Lab
Gene Symbol Vdac3-ps1
Ensembl Gene ENSMUSG00000075053
Gene Namevoltage-dependent anion channel 3, pseudogene 1
SynonymsENSMUSG00000075053
MMRRC Submission 039358-MU
Accession Numbers
Is this an essential gene? Possibly non essential (E-score: 0.417) question?
Stock #R1292 (G1)
Quality Score225
Status Validated
Chromosome13
Chromosomal Location18030324-18031629 bp(-) (GRCm38)
Type of Mutationexon
DNA Base Change (assembly) T to C at 18031295 bp
ZygosityHeterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s):
Predicted Effect noncoding transcript
Transcript: ENSMUST00000099736
SMART Domains Protein: ENSMUSP00000137236
Gene: ENSMUSG00000075053

DomainStartEndE-ValueType
Pfam:Porin_3 3 276 4.8e-85 PFAM
Meta Mutation Damage Score 0.0869 question?
Coding Region Coverage
  • 1x: 99.1%
  • 3x: 98.4%
  • 10x: 97.0%
  • 20x: 94.7%
Validation Efficiency 97% (31/32)
Allele List at MGI
Other mutations in this stock
Total: 29 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930550C14Rik T A 9: 53,425,619 D74E probably benign Het
9530053A07Rik A C 7: 28,142,794 probably benign Het
Abcb1a A T 5: 8,713,343 T624S probably benign Het
Atp8b1 T C 18: 64,571,021 Y342C probably damaging Het
Clcnka A G 4: 141,395,592 probably benign Het
Cma2 C T 14: 55,973,742 R164C probably damaging Het
Cnga1 T C 5: 72,604,683 D496G probably damaging Het
Ctbp2 T A 7: 133,015,189 R6W probably damaging Het
Cyp3a11 T C 5: 145,865,994 T230A probably benign Het
Defb40 A C 8: 18,978,064 I18S probably benign Het
Gm10036 T G 18: 15,833,311 I173S possibly damaging Het
Herc2 A T 7: 56,197,203 I3634L probably benign Het
Igfbp1 A G 11: 7,200,863 N218S probably damaging Het
Jag1 C G 2: 137,083,473 V1070L possibly damaging Het
Kmt2a A T 9: 44,814,694 probably benign Het
Ly9 T C 1: 171,589,103 probably null Het
Mut C A 17: 40,941,407 A280E probably damaging Het
Olfr180 C T 16: 58,915,771 R290K probably damaging Het
Olfr231 A G 1: 174,117,854 F54S probably benign Het
Pcdhb13 T C 18: 37,443,832 V421A probably benign Het
Pik3ca T A 3: 32,454,420 L779Q probably damaging Het
Plxnd1 T C 6: 115,962,683 probably benign Het
Prss16 T A 13: 22,009,521 K35* probably null Het
Rhbdl2 G A 4: 123,829,642 A280T possibly damaging Het
Slc2a2 C T 3: 28,717,488 T189I probably damaging Het
Srsf6 C T 2: 162,934,483 probably benign Het
Tacr1 A G 6: 82,554,875 I251V probably damaging Het
Tln1 A G 4: 43,534,578 probably null Het
Zfp458 A T 13: 67,256,690 C562S probably damaging Het
Other mutations in Vdac3-ps1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01133:Vdac3-ps1 APN 13 18031449 exon noncoding transcript
IGL01530:Vdac3-ps1 APN 13 18031506 exon noncoding transcript
IGL02001:Vdac3-ps1 APN 13 18031388 exon noncoding transcript
IGL02028:Vdac3-ps1 APN 13 18030884 exon noncoding transcript
IGL02275:Vdac3-ps1 APN 13 18030794 exon noncoding transcript
IGL02965:Vdac3-ps1 APN 13 18030846 exon noncoding transcript
R4582:Vdac3-ps1 UTSW 13 18031592 exon noncoding transcript
R5941:Vdac3-ps1 UTSW 13 18031202 exon noncoding transcript
Predicted Primers PCR Primer
(F):5'- TGAGCCTCCAAACTCAGTGCCATC -3'
(R):5'- AGGAGAGTGGCTGTGAGATTTACCC -3'

Sequencing Primer
(F):5'- GGCTGTGTCAAAACTCATCTG -3'
(R):5'- GGCTGTGAGATTTACCCCAAATG -3'
Posted On2014-01-29