Incidental Mutation 'R1275:Vmn1r234'
| ID |
150875 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Vmn1r234
|
| Ensembl Gene |
ENSMUSG00000057203 |
| Gene Name |
vomeronasal 1 receptor 234 |
| Synonyms |
V1rf1 |
| MMRRC Submission |
039341-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.058)
|
| Stock # |
R1275 (G1)
|
| Quality Score |
217 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
21449088-21450078 bp(+) (GRCm39) |
| Type of Mutation |
frame shift |
| DNA Base Change (assembly) |
CTT to CTTT
at 21449513 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000078579
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000079633]
|
| AlphaFold |
Q8R298 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000079633
|
| SMART Domains |
Protein: ENSMUSP00000078579
Gene: ENSMUSG00000057203
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
25 |
315 |
2.8e-14 |
PFAM |
|
Pfam:V1R
|
57 |
318 |
2.3e-26 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000177028
|
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.3%
- 10x: 96.3%
- 20x: 92.6%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 17 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Cdhr18 |
T |
C |
14: 13,896,949 (GRCm38) |
Y142C |
probably damaging |
Het |
| Clstn2 |
C |
T |
9: 97,339,483 (GRCm39) |
V793I |
probably benign |
Het |
| Coro1a |
C |
T |
7: 126,299,755 (GRCm39) |
|
probably null |
Het |
| Dync1h1 |
G |
A |
12: 110,602,943 (GRCm39) |
E2195K |
probably benign |
Het |
| Efcab14 |
T |
G |
4: 115,613,670 (GRCm39) |
L206R |
probably damaging |
Het |
| Ehmt1 |
A |
G |
2: 24,777,007 (GRCm39) |
|
probably null |
Het |
| Fosl2 |
C |
T |
5: 32,307,798 (GRCm39) |
R130W |
probably damaging |
Het |
| Gfral |
A |
G |
9: 76,104,314 (GRCm39) |
C233R |
probably damaging |
Het |
| Ino80 |
T |
C |
2: 119,257,536 (GRCm39) |
T765A |
probably benign |
Het |
| Mindy3 |
A |
T |
2: 12,400,984 (GRCm39) |
|
probably null |
Het |
| Myo15b |
CGGAGGAGGAGGAGGAGGAG |
CGGAGGAGGAGGAGGAG |
11: 115,774,318 (GRCm39) |
|
probably benign |
Het |
| Nup50l |
T |
C |
6: 96,142,099 (GRCm39) |
E315G |
probably benign |
Het |
| Osbpl11 |
T |
A |
16: 33,006,220 (GRCm39) |
M16K |
probably benign |
Het |
| Rassf7 |
T |
A |
7: 140,797,060 (GRCm39) |
L91Q |
probably damaging |
Het |
| Shld1 |
T |
C |
2: 132,534,015 (GRCm39) |
S48P |
probably benign |
Het |
| Unc13b |
A |
G |
4: 43,235,366 (GRCm39) |
K3318R |
probably damaging |
Het |
| Zfp930 |
A |
G |
8: 69,680,631 (GRCm39) |
K108E |
possibly damaging |
Het |
|
| Other mutations in Vmn1r234 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00089:Vmn1r234
|
APN |
17 |
21,449,860 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01485:Vmn1r234
|
APN |
17 |
21,449,171 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
IGL02149:Vmn1r234
|
APN |
17 |
21,449,269 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02291:Vmn1r234
|
APN |
17 |
21,449,193 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL02993:Vmn1r234
|
APN |
17 |
21,449,965 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03223:Vmn1r234
|
APN |
17 |
21,449,653 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0626:Vmn1r234
|
UTSW |
17 |
21,450,007 (GRCm39) |
missense |
probably benign |
0.17 |
|
R1274:Vmn1r234
|
UTSW |
17 |
21,449,513 (GRCm39) |
frame shift |
probably null |
|
|
R1288:Vmn1r234
|
UTSW |
17 |
21,449,513 (GRCm39) |
frame shift |
probably null |
|
|
R1289:Vmn1r234
|
UTSW |
17 |
21,449,513 (GRCm39) |
frame shift |
probably null |
|
|
R1319:Vmn1r234
|
UTSW |
17 |
21,449,172 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1412:Vmn1r234
|
UTSW |
17 |
21,449,512 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2323:Vmn1r234
|
UTSW |
17 |
21,449,965 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3755:Vmn1r234
|
UTSW |
17 |
21,449,271 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4299:Vmn1r234
|
UTSW |
17 |
21,449,283 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5301:Vmn1r234
|
UTSW |
17 |
21,449,589 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5741:Vmn1r234
|
UTSW |
17 |
21,449,731 (GRCm39) |
missense |
probably benign |
0.21 |
|
R6197:Vmn1r234
|
UTSW |
17 |
21,449,589 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6218:Vmn1r234
|
UTSW |
17 |
21,449,983 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6486:Vmn1r234
|
UTSW |
17 |
21,449,604 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7482:Vmn1r234
|
UTSW |
17 |
21,449,637 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7635:Vmn1r234
|
UTSW |
17 |
21,449,479 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8295:Vmn1r234
|
UTSW |
17 |
21,449,101 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9506:Vmn1r234
|
UTSW |
17 |
21,449,503 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9530:Vmn1r234
|
UTSW |
17 |
21,449,104 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0028:Vmn1r234
|
UTSW |
17 |
21,449,152 (GRCm39) |
missense |
probably benign |
0.17 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCACAAGCAATGGCAGCTTTTGG -3'
(R):5'- CTGTGCCTGTGCAAAATGAGAACC -3'
Sequencing Primer
(F):5'- CAATGGCAGCTTTTGGTTTTCAATG -3'
(R):5'- ACATTGCACAATTTTGCAGACA -3'
|
| Posted On |
2014-01-29 |
Incidental Mutation