Incidental Mutation 'IGL01744:Ceacam11'
ID152963
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Ceacam11
Ensembl Gene ENSMUSG00000030368
Gene Namecarcinoembryonic antigen-related cell adhesion molecule 11
SynonymsCeacam11-C1, Ceacam11-C3, Ceacam11-C4, 1600015D01Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.034) question?
Stock #IGL01744
Quality Score
Status
Chromosome7
Chromosomal Location17972124-17978556 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 17973398 bp
ZygosityHeterozygous
Amino Acid Change Isoleucine to Phenylalanine at position 36 (I36F)
Ref Sequence ENSEMBL: ENSMUSP00000092393 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000094799]
Predicted Effect possibly damaging
Transcript: ENSMUST00000094799
AA Change: I36F

PolyPhen 2 Score 0.946 (Sensitivity: 0.80; Specificity: 0.95)
SMART Domains Protein: ENSMUSP00000092393
Gene: ENSMUSG00000030368
AA Change: I36F

DomainStartEndE-ValueType
IG_like 40 141 8.06e0 SMART
IG_like 160 261 8.5e0 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 33 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2900092C05Rik T C 7: 12,550,532 I102T possibly damaging Het
4933412E24Rik C A 15: 60,015,575 A339S possibly damaging Het
Ackr2 A G 9: 121,909,119 T187A probably benign Het
Adam28 A G 14: 68,607,507 V777A probably benign Het
Add3 T A 19: 53,239,430 D515E probably damaging Het
Aire C A 10: 78,036,723 E354* probably null Het
AW551984 T C 9: 39,591,272 K670R probably benign Het
Bahcc1 T C 11: 120,271,737 V287A probably benign Het
Brca1 T C 11: 101,524,176 N1044S possibly damaging Het
Bub1b T A 2: 118,636,749 I851N probably damaging Het
Copa A G 1: 172,113,189 E714G probably benign Het
Cth A T 3: 157,924,935 N32K probably benign Het
Cyp2a5 T A 7: 26,841,009 M349K probably damaging Het
D130052B06Rik A G 11: 33,623,966 S188G unknown Het
Fhdc1 G A 3: 84,444,735 A1061V possibly damaging Het
Flt1 T C 5: 147,571,461 N1161S probably benign Het
Gm10696 T A 3: 94,176,237 K89M probably damaging Het
Hip1 T C 5: 135,545,063 probably benign Het
Mapk11 A G 15: 89,146,843 probably benign Het
Mtif2 A G 11: 29,544,417 probably benign Het
Myo1f C A 17: 33,583,680 probably benign Het
Nipsnap1 G A 11: 4,889,912 R211H probably damaging Het
Olfr599 A G 7: 103,338,228 H58R probably damaging Het
Olfr781 T C 10: 129,333,457 I192T probably benign Het
Pcdh1 A T 18: 38,203,249 I111N probably damaging Het
Piezo2 T A 18: 63,042,788 I1841F probably damaging Het
Pirb G T 7: 3,717,176 Y399* probably null Het
Ppp1r36 A T 12: 76,439,232 N388I possibly damaging Het
Prr16 A G 18: 51,302,989 D180G possibly damaging Het
Prss39 A G 1: 34,502,199 probably null Het
Trank1 T A 9: 111,349,363 V373D probably damaging Het
Ubn1 A G 16: 5,072,059 E186G probably damaging Het
Zmym2 T C 14: 56,946,572 V997A probably benign Het
Other mutations in Ceacam11
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00844:Ceacam11 APN 7 17973670 missense possibly damaging 0.82
IGL01161:Ceacam11 APN 7 17978510 missense possibly damaging 0.95
IGL02052:Ceacam11 APN 7 17973623 missense probably benign 0.09
IGL02337:Ceacam11 APN 7 17973625 missense probably benign 0.09
IGL03079:Ceacam11 APN 7 17978436 missense probably benign 0.02
R1902:Ceacam11 UTSW 7 17975327 missense probably benign 0.05
R2204:Ceacam11 UTSW 7 17975348 missense possibly damaging 0.92
R2851:Ceacam11 UTSW 7 17978526 missense probably benign 0.01
R3237:Ceacam11 UTSW 7 17973454 missense probably benign 0.02
R4786:Ceacam11 UTSW 7 17972314 critical splice donor site probably null
Posted On2014-02-04