Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01758:Vmn2r92'

153474

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r92

Ensembl Gene

ENSMUSG00000091350

Gene Name

vomeronasal 2, receptor 92

Synonyms

EG627111

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.082) question?

Stock #

IGL01758

Quality Score

Status

Chromosome

Chromosomal Location

18151887-18188886 bp(+) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

T to A at 18152013 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Cysteine to Stop codon at position 28 (C28*)

Ref Sequence

ENSEMBL: ENSMUSP00000128685 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000169686]

AlphaFold

L7N2A4

Predicted Effect

probably null
Transcript: ENSMUST00000169686
AA Change: C28*

SMART Domains

Protein: ENSMUSP00000128685
Gene: ENSMUSG00000091350
AA Change: C28*

Domain	Start	End	E-Value	Type
signal peptide	1	20	N/A	INTRINSIC
Pfam:ANF_receptor	83	463	4.7e-38	PFAM
Pfam:NCD3G	510	564	2.5e-19	PFAM
Pfam:7tm_3	597	832	1.1e-52	PFAM
low complexity region	843	855	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 30 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aatk	T	C	11: 120,010,819	D860G	possibly damaging	Het
Acot7	T	C	4: 152,217,793	C121R	probably damaging	Het
Adam19	A	T	11: 46,112,924	H193L	probably benign	Het
AI661453	T	A	17: 47,466,623		probably benign	Het
Bod1l	T	C	5: 41,826,610		probably benign	Het
Brd4	T	C	17: 32,212,829		probably benign	Het
Capn12	G	A	7: 28,886,623		probably null	Het
Cdh18	A	G	15: 23,474,183	Q713R	probably benign	Het
Cfap52	A	T	11: 67,953,580	L103Q	possibly damaging	Het
Dpy19l4	T	A	4: 11,265,846	T475S	probably damaging	Het
Fat2	A	T	11: 55,296,209	D1270E	probably damaging	Het
Hfm1	T	C	5: 106,904,793	K275E	probably damaging	Het
Ift172	T	C	5: 31,280,714	D426G	probably benign	Het
Mrc1	T	C	2: 14,238,248	S62P	probably damaging	Het
Olfr275	G	T	4: 52,825,468	E24*	probably null	Het
Olfr914	T	A	9: 38,607,293	I276K	probably damaging	Het
Ptgs2	A	T	1: 150,101,989		probably null	Het
Rxfp1	T	A	3: 79,652,216	I433F	possibly damaging	Het
Sbf1	C	T	15: 89,303,215		probably benign	Het
Serpinb13	T	G	1: 107,000,754	F368C	probably damaging	Het
Slc9c1	T	A	16: 45,541,461	S80R	probably damaging	Het
Spats2l	G	T	1: 57,879,556	V30L	probably damaging	Het
Stat1	A	G	1: 52,136,921	E195G	probably damaging	Het
Tbx5	T	A	5: 119,844,958		probably benign	Het
Tmem165	A	G	5: 76,204,163	T164A	probably damaging	Het
Trim66	A	T	7: 109,486,045		probably null	Het
Trip10	T	A	17: 57,261,409	V405E	possibly damaging	Het
Wdr60	G	A	12: 116,218,798	P728L	possibly damaging	Het
Zbtb8a	C	T	4: 129,357,847	C277Y	probably damaging	Het
Zfp638	T	C	6: 83,979,526	F1705S	probably damaging	Het

Other mutations in Vmn2r92

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01591:Vmn2r92	APN	17	18185161	missense	unknown
IGL02614:Vmn2r92	APN	17	18167241	splice site	probably benign
IGL03095:Vmn2r92	APN	17	18166710	missense	possibly damaging	0.55
IGL03403:Vmn2r92	APN	17	18166852	missense	probably damaging	0.98
R0133:Vmn2r92	UTSW	17	18167957	missense	probably damaging	1.00
R0225:Vmn2r92	UTSW	17	18167957	missense	probably damaging	1.00
R0227:Vmn2r92	UTSW	17	18167957	missense	probably damaging	1.00
R0265:Vmn2r92	UTSW	17	18167957	missense	probably damaging	1.00
R0266:Vmn2r92	UTSW	17	18167957	missense	probably damaging	1.00
R0267:Vmn2r92	UTSW	17	18167957	missense	probably damaging	1.00
R0420:Vmn2r92	UTSW	17	18168921	missense	probably benign	0.01
R0426:Vmn2r92	UTSW	17	18167957	missense	probably damaging	1.00
R0494:Vmn2r92	UTSW	17	18167957	missense	probably damaging	1.00
R1253:Vmn2r92	UTSW	17	18166766	missense	probably benign	0.08
R1497:Vmn2r92	UTSW	17	18167363	missense	probably benign	0.02
R1571:Vmn2r92	UTSW	17	18152090	missense	probably damaging	0.96
R1656:Vmn2r92	UTSW	17	18151936	missense	probably benign
R1816:Vmn2r92	UTSW	17	18166677	missense	probably damaging	0.98
R2229:Vmn2r92	UTSW	17	18167392	missense	probably benign	0.01
R2909:Vmn2r92	UTSW	17	18185115	missense	possibly damaging	0.89
R3694:Vmn2r92	UTSW	17	18151943	nonsense	probably null
R4207:Vmn2r92	UTSW	17	18184261	missense	possibly damaging	0.62
R4548:Vmn2r92	UTSW	17	18171316	missense	probably benign
R4612:Vmn2r92	UTSW	17	18166870	missense	probably benign	0.25
R4742:Vmn2r92	UTSW	17	18166857	missense	probably benign	0.06
R4824:Vmn2r92	UTSW	17	18151921	utr 5 prime	probably benign
R4865:Vmn2r92	UTSW	17	18167372	missense	probably benign	0.16
R4900:Vmn2r92	UTSW	17	18184343	missense	probably benign	0.27
R5084:Vmn2r92	UTSW	17	18185177	makesense	probably null
R5140:Vmn2r92	UTSW	17	18152050	missense	probably benign	0.07
R5995:Vmn2r92	UTSW	17	18168951	critical splice donor site	probably null
R6045:Vmn2r92	UTSW	17	18168043	critical splice donor site	probably null
R6269:Vmn2r92	UTSW	17	18166774	missense	probably benign	0.01
R6877:Vmn2r92	UTSW	17	18168822	missense	probably damaging	1.00
R7151:Vmn2r92	UTSW	17	18166743	missense	probably benign	0.01
R7260:Vmn2r92	UTSW	17	18166876	missense	probably damaging	1.00
R7344:Vmn2r92	UTSW	17	18167251	missense	probably benign	0.01
R7514:Vmn2r92	UTSW	17	18171271	missense	probably damaging	1.00
R7576:Vmn2r92	UTSW	17	18167359	missense	probably benign	0.01
R7584:Vmn2r92	UTSW	17	18166766	missense	probably benign	0.08
R7912:Vmn2r92	UTSW	17	18184708	missense	possibly damaging	0.91
R7941:Vmn2r92	UTSW	17	18184837	missense	possibly damaging	0.89
R8178:Vmn2r92	UTSW	17	18166726	missense	possibly damaging	0.69
R8238:Vmn2r92	UTSW	17	18185016	missense	probably benign	0.00
R8239:Vmn2r92	UTSW	17	18185016	missense	probably benign	0.00
R8252:Vmn2r92	UTSW	17	18166872	missense	probably damaging	1.00
R8322:Vmn2r92	UTSW	17	18166624	missense	probably damaging	0.99
R8355:Vmn2r92	UTSW	17	18184799	missense	probably damaging	0.99
R9399:Vmn2r92	UTSW	17	18168875	missense	probably benign	0.29
R9639:Vmn2r92	UTSW	17	18152090	missense	probably damaging	0.96
R9747:Vmn2r92	UTSW	17	18184939	missense	possibly damaging	0.66
R9773:Vmn2r92	UTSW	17	18166687	missense	probably damaging	1.00
X0066:Vmn2r92	UTSW	17	18184895	missense	probably damaging	1.00
Z1177:Vmn2r92	UTSW	17	18184533	missense	probably damaging	0.96

Posted On

2014-02-04