Incidental Mutation 'IGL01758:Vmn2r92'
ID 153474
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn2r92
Ensembl Gene ENSMUSG00000091350
Gene Name vomeronasal 2, receptor 92
Synonyms EG627111
Accession Numbers
Essential gene? Probably non essential (E-score: 0.082) question?
Stock # IGL01758
Quality Score
Status
Chromosome 17
Chromosomal Location 18372192-18405440 bp(+) (GRCm39)
Type of Mutation nonsense
DNA Base Change (assembly) T to A at 18372275 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change Cysteine to Stop codon at position 28 (C28*)
Ref Sequence ENSEMBL: ENSMUSP00000128685 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000169686]
AlphaFold L7N2A4
Predicted Effect probably null
Transcript: ENSMUST00000169686
AA Change: C28*
SMART Domains Protein: ENSMUSP00000128685
Gene: ENSMUSG00000091350
AA Change: C28*

DomainStartEndE-ValueType
signal peptide 1 20 N/A INTRINSIC
Pfam:ANF_receptor 83 463 4.7e-38 PFAM
Pfam:NCD3G 510 564 2.5e-19 PFAM
Pfam:7tm_3 597 832 1.1e-52 PFAM
low complexity region 843 855 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 30 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Aatk T C 11: 119,901,645 (GRCm39) D860G possibly damaging Het
Acot7 T C 4: 152,302,250 (GRCm39) C121R probably damaging Het
Adam19 A T 11: 46,003,751 (GRCm39) H193L probably benign Het
AI661453 T A 17: 47,777,548 (GRCm39) probably benign Het
Bod1l T C 5: 41,983,953 (GRCm39) probably benign Het
Brd4 T C 17: 32,431,803 (GRCm39) probably benign Het
Capn12 G A 7: 28,586,048 (GRCm39) probably null Het
Cdh18 A G 15: 23,474,269 (GRCm39) Q713R probably benign Het
Cfap52 A T 11: 67,844,406 (GRCm39) L103Q possibly damaging Het
Dpy19l4 T A 4: 11,265,846 (GRCm39) T475S probably damaging Het
Dync2i1 G A 12: 116,182,418 (GRCm39) P728L possibly damaging Het
Fat2 A T 11: 55,187,035 (GRCm39) D1270E probably damaging Het
Hfm1 T C 5: 107,052,659 (GRCm39) K275E probably damaging Het
Ift172 T C 5: 31,438,058 (GRCm39) D426G probably benign Het
Mrc1 T C 2: 14,243,059 (GRCm39) S62P probably damaging Het
Or13f5 G T 4: 52,825,468 (GRCm39) E24* probably null Het
Or8b50 T A 9: 38,518,589 (GRCm39) I276K probably damaging Het
Ptgs2 A T 1: 149,977,740 (GRCm39) probably null Het
Rxfp1 T A 3: 79,559,523 (GRCm39) I433F possibly damaging Het
Sbf1 C T 15: 89,187,418 (GRCm39) probably benign Het
Serpinb13 T G 1: 106,928,484 (GRCm39) F368C probably damaging Het
Slc9c1 T A 16: 45,361,824 (GRCm39) S80R probably damaging Het
Spats2l G T 1: 57,918,715 (GRCm39) V30L probably damaging Het
Stat1 A G 1: 52,176,080 (GRCm39) E195G probably damaging Het
Tbx5 T A 5: 119,983,023 (GRCm39) probably benign Het
Tmem165 A G 5: 76,352,010 (GRCm39) T164A probably damaging Het
Trim66 A T 7: 109,085,252 (GRCm39) probably null Het
Trip10 T A 17: 57,568,409 (GRCm39) V405E possibly damaging Het
Zbtb8a C T 4: 129,251,640 (GRCm39) C277Y probably damaging Het
Zfp638 T C 6: 83,956,508 (GRCm39) F1705S probably damaging Het
Other mutations in Vmn2r92
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01591:Vmn2r92 APN 17 18,405,423 (GRCm39) missense unknown
IGL02614:Vmn2r92 APN 17 18,387,503 (GRCm39) splice site probably benign
IGL03095:Vmn2r92 APN 17 18,386,972 (GRCm39) missense possibly damaging 0.55
IGL03403:Vmn2r92 APN 17 18,387,114 (GRCm39) missense probably damaging 0.98
R0133:Vmn2r92 UTSW 17 18,388,219 (GRCm39) missense probably damaging 1.00
R0225:Vmn2r92 UTSW 17 18,388,219 (GRCm39) missense probably damaging 1.00
R0227:Vmn2r92 UTSW 17 18,388,219 (GRCm39) missense probably damaging 1.00
R0265:Vmn2r92 UTSW 17 18,388,219 (GRCm39) missense probably damaging 1.00
R0266:Vmn2r92 UTSW 17 18,388,219 (GRCm39) missense probably damaging 1.00
R0267:Vmn2r92 UTSW 17 18,388,219 (GRCm39) missense probably damaging 1.00
R0420:Vmn2r92 UTSW 17 18,389,183 (GRCm39) missense probably benign 0.01
R0426:Vmn2r92 UTSW 17 18,388,219 (GRCm39) missense probably damaging 1.00
R0494:Vmn2r92 UTSW 17 18,388,219 (GRCm39) missense probably damaging 1.00
R1253:Vmn2r92 UTSW 17 18,387,028 (GRCm39) missense probably benign 0.08
R1497:Vmn2r92 UTSW 17 18,387,625 (GRCm39) missense probably benign 0.02
R1571:Vmn2r92 UTSW 17 18,372,352 (GRCm39) missense probably damaging 0.96
R1656:Vmn2r92 UTSW 17 18,372,198 (GRCm39) missense probably benign
R1816:Vmn2r92 UTSW 17 18,386,939 (GRCm39) missense probably damaging 0.98
R2229:Vmn2r92 UTSW 17 18,387,654 (GRCm39) missense probably benign 0.01
R2909:Vmn2r92 UTSW 17 18,405,377 (GRCm39) missense possibly damaging 0.89
R3694:Vmn2r92 UTSW 17 18,372,205 (GRCm39) nonsense probably null
R4207:Vmn2r92 UTSW 17 18,404,523 (GRCm39) missense possibly damaging 0.62
R4548:Vmn2r92 UTSW 17 18,391,578 (GRCm39) missense probably benign
R4612:Vmn2r92 UTSW 17 18,387,132 (GRCm39) missense probably benign 0.25
R4742:Vmn2r92 UTSW 17 18,387,119 (GRCm39) missense probably benign 0.06
R4824:Vmn2r92 UTSW 17 18,372,183 (GRCm39) utr 5 prime probably benign
R4865:Vmn2r92 UTSW 17 18,387,634 (GRCm39) missense probably benign 0.16
R4900:Vmn2r92 UTSW 17 18,404,605 (GRCm39) missense probably benign 0.27
R5084:Vmn2r92 UTSW 17 18,405,439 (GRCm39) makesense probably null
R5140:Vmn2r92 UTSW 17 18,372,312 (GRCm39) missense probably benign 0.07
R5995:Vmn2r92 UTSW 17 18,389,213 (GRCm39) critical splice donor site probably null
R6045:Vmn2r92 UTSW 17 18,388,305 (GRCm39) critical splice donor site probably null
R6269:Vmn2r92 UTSW 17 18,387,036 (GRCm39) missense probably benign 0.01
R6877:Vmn2r92 UTSW 17 18,389,084 (GRCm39) missense probably damaging 1.00
R7151:Vmn2r92 UTSW 17 18,387,005 (GRCm39) missense probably benign 0.01
R7260:Vmn2r92 UTSW 17 18,387,138 (GRCm39) missense probably damaging 1.00
R7344:Vmn2r92 UTSW 17 18,387,513 (GRCm39) missense probably benign 0.01
R7514:Vmn2r92 UTSW 17 18,391,533 (GRCm39) missense probably damaging 1.00
R7576:Vmn2r92 UTSW 17 18,387,621 (GRCm39) missense probably benign 0.01
R7584:Vmn2r92 UTSW 17 18,387,028 (GRCm39) missense probably benign 0.08
R7912:Vmn2r92 UTSW 17 18,404,970 (GRCm39) missense possibly damaging 0.91
R7941:Vmn2r92 UTSW 17 18,405,099 (GRCm39) missense possibly damaging 0.89
R8178:Vmn2r92 UTSW 17 18,386,988 (GRCm39) missense possibly damaging 0.69
R8238:Vmn2r92 UTSW 17 18,405,278 (GRCm39) missense probably benign 0.00
R8239:Vmn2r92 UTSW 17 18,405,278 (GRCm39) missense probably benign 0.00
R8252:Vmn2r92 UTSW 17 18,387,134 (GRCm39) missense probably damaging 1.00
R8322:Vmn2r92 UTSW 17 18,386,886 (GRCm39) missense probably damaging 0.99
R8355:Vmn2r92 UTSW 17 18,405,061 (GRCm39) missense probably damaging 0.99
R9399:Vmn2r92 UTSW 17 18,389,137 (GRCm39) missense probably benign 0.29
R9639:Vmn2r92 UTSW 17 18,372,352 (GRCm39) missense probably damaging 0.96
R9747:Vmn2r92 UTSW 17 18,405,201 (GRCm39) missense possibly damaging 0.66
R9773:Vmn2r92 UTSW 17 18,386,949 (GRCm39) missense probably damaging 1.00
X0066:Vmn2r92 UTSW 17 18,405,157 (GRCm39) missense probably damaging 1.00
Z1177:Vmn2r92 UTSW 17 18,404,795 (GRCm39) missense probably damaging 0.96
Posted On 2014-02-04