Incidental Mutation 'IGL01773:Vmn1r209'
| ID |
153712 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r209
|
| Ensembl Gene |
ENSMUSG00000071491 |
| Gene Name |
vomeronasal 1 receptor 209 |
| Synonyms |
Gm11315 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.096)
|
| Stock # |
IGL01773
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
13 |
| Chromosomal Location |
22989750-22990688 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 22990450 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Tyrosine
at position 80
(C80Y)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000153997
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000095961]
[ENSMUST00000227038]
[ENSMUST00000227265]
|
| AlphaFold |
Q5NC97 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000095961
AA Change: C80Y
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000093657
Gene: ENSMUSG00000071491
AA Change: C80Y
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
2 |
294 |
9.8e-9 |
PFAM |
|
Pfam:V1R
|
34 |
297 |
3e-36 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000227038
AA Change: C80Y
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000227265
AA Change: C80Y
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 30 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Cacna1s |
C |
A |
1: 136,046,491 (GRCm39) |
H1775Q |
probably benign |
Het |
| Calcrl |
A |
G |
2: 84,200,787 (GRCm39) |
Y86H |
probably benign |
Het |
| Ccdc63 |
T |
C |
5: 122,251,208 (GRCm39) |
K401E |
possibly damaging |
Het |
| Col9a1 |
A |
G |
1: 24,244,147 (GRCm39) |
T127A |
probably benign |
Het |
| Cpq |
T |
A |
15: 33,212,996 (GRCm39) |
F5Y |
probably benign |
Het |
| Cuzd1 |
T |
A |
7: 130,916,614 (GRCm39) |
M282L |
probably damaging |
Het |
| Ddx10 |
C |
A |
9: 53,115,430 (GRCm39) |
D635Y |
possibly damaging |
Het |
| Ect2l |
T |
C |
10: 18,037,252 (GRCm39) |
D382G |
probably damaging |
Het |
| Ganc |
T |
C |
2: 120,290,365 (GRCm39) |
S901P |
possibly damaging |
Het |
| Gpr179 |
G |
A |
11: 97,232,192 (GRCm39) |
R671C |
probably benign |
Het |
| Isl2 |
T |
C |
9: 55,451,504 (GRCm39) |
L219P |
probably damaging |
Het |
| Mfsd13a |
T |
C |
19: 46,357,733 (GRCm39) |
S296P |
possibly damaging |
Het |
| Mtmr7 |
A |
T |
8: 41,034,461 (GRCm39) |
L287Q |
probably damaging |
Het |
| Or11g25 |
T |
C |
14: 50,723,230 (GRCm39) |
F105S |
probably damaging |
Het |
| Or52d13 |
T |
G |
7: 103,110,221 (GRCm39) |
M60L |
possibly damaging |
Het |
| Or7a39 |
A |
G |
10: 78,715,770 (GRCm39) |
T255A |
possibly damaging |
Het |
| Or8g28 |
A |
G |
9: 39,169,830 (GRCm39) |
I46T |
probably damaging |
Het |
| Pik3c3 |
T |
A |
18: 30,410,155 (GRCm39) |
F130I |
probably damaging |
Het |
| Rab3gap1 |
T |
A |
1: 127,845,958 (GRCm39) |
S277R |
possibly damaging |
Het |
| Rassf9 |
A |
G |
10: 102,381,494 (GRCm39) |
K290R |
probably benign |
Het |
| Rnaseh2a |
A |
T |
8: 85,691,767 (GRCm39) |
V136D |
probably damaging |
Het |
| Rnf39 |
C |
T |
17: 37,256,328 (GRCm39) |
S140L |
possibly damaging |
Het |
| Sbno2 |
A |
G |
10: 79,893,665 (GRCm39) |
V1212A |
probably damaging |
Het |
| Slc4a10 |
A |
T |
2: 62,021,101 (GRCm39) |
I50F |
probably damaging |
Het |
| Slfn5 |
A |
T |
11: 82,852,157 (GRCm39) |
E761V |
probably damaging |
Het |
| Sptlc1 |
A |
G |
13: 53,531,334 (GRCm39) |
Y18H |
probably damaging |
Het |
| Tfam |
A |
G |
10: 71,072,805 (GRCm39) |
M9T |
possibly damaging |
Het |
| Tmem186 |
A |
G |
16: 8,453,841 (GRCm39) |
L140P |
probably damaging |
Het |
| Try4 |
A |
T |
6: 41,281,960 (GRCm39) |
N182I |
probably damaging |
Het |
| Vmn2r104 |
A |
T |
17: 20,260,930 (GRCm39) |
S498T |
probably benign |
Het |
|
| Other mutations in Vmn1r209 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01788:Vmn1r209
|
APN |
13 |
22,989,832 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02738:Vmn1r209
|
APN |
13 |
22,990,290 (GRCm39) |
nonsense |
probably null |
|
|
IGL03177:Vmn1r209
|
APN |
13 |
22,990,024 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
IGL03199:Vmn1r209
|
APN |
13 |
22,990,220 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0437:Vmn1r209
|
UTSW |
13 |
22,990,526 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0497:Vmn1r209
|
UTSW |
13 |
22,990,118 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0506:Vmn1r209
|
UTSW |
13 |
22,990,114 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1496:Vmn1r209
|
UTSW |
13 |
22,989,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1644:Vmn1r209
|
UTSW |
13 |
22,990,652 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R1829:Vmn1r209
|
UTSW |
13 |
22,990,409 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R2360:Vmn1r209
|
UTSW |
13 |
22,989,836 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3434:Vmn1r209
|
UTSW |
13 |
22,990,267 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3435:Vmn1r209
|
UTSW |
13 |
22,990,267 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4082:Vmn1r209
|
UTSW |
13 |
22,989,785 (GRCm39) |
missense |
probably null |
0.15 |
|
R4451:Vmn1r209
|
UTSW |
13 |
22,990,668 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4616:Vmn1r209
|
UTSW |
13 |
22,990,135 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4618:Vmn1r209
|
UTSW |
13 |
22,990,619 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4801:Vmn1r209
|
UTSW |
13 |
22,989,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4802:Vmn1r209
|
UTSW |
13 |
22,989,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6035:Vmn1r209
|
UTSW |
13 |
22,990,202 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6035:Vmn1r209
|
UTSW |
13 |
22,990,202 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6908:Vmn1r209
|
UTSW |
13 |
22,990,400 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R7162:Vmn1r209
|
UTSW |
13 |
22,990,128 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7772:Vmn1r209
|
UTSW |
13 |
22,990,664 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R8328:Vmn1r209
|
UTSW |
13 |
22,990,643 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8335:Vmn1r209
|
UTSW |
13 |
22,989,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8903:Vmn1r209
|
UTSW |
13 |
22,990,684 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8919:Vmn1r209
|
UTSW |
13 |
22,990,223 (GRCm39) |
missense |
probably benign |
|
|
R8932:Vmn1r209
|
UTSW |
13 |
22,990,343 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9307:Vmn1r209
|
UTSW |
13 |
22,990,072 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9343:Vmn1r209
|
UTSW |
13 |
22,990,546 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Posted On |
2014-02-04 |
Incidental Mutation