Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01785:Clec2e'

153789

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Clec2e

Ensembl Gene

ENSMUSG00000030155

Gene Name

C-type lectin domain family 2, member e

Synonyms

Clra

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.049) question?

Stock #

IGL01785

Quality Score

Status

Chromosome

Chromosomal Location

129068961-129077876 bp(-) (GRCm39)

Type of Mutation

utr 3 prime

DNA Base Change (assembly)

A to T at 129070364 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000032258 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000032258]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000032258

SMART Domains

Protein: ENSMUSP00000032258
Gene: ENSMUSG00000030155

Domain	Start	End	E-Value	Type
transmembrane domain	49	71	N/A	INTRINSIC
CLECT	89	200	1.03e-21	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 30 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcb4	T	A	5: 8,965,058 (GRCm39)	Y309*	probably null	Het
Abhd18	G	A	3: 40,860,339 (GRCm39)	R42Q	probably damaging	Het
Ano3	T	A	2: 110,513,060 (GRCm39)	Q645L	probably damaging	Het
Clasp1	T	A	1: 118,425,466 (GRCm39)	L272Q	possibly damaging	Het
Clec1b	A	G	6: 129,380,525 (GRCm39)	D115G	probably damaging	Het
Corin	T	C	5: 72,497,219 (GRCm39)	N532S	probably damaging	Het
Csn1s2b	A	G	5: 87,957,772 (GRCm39)	K2R	possibly damaging	Het
Mcm8	A	G	2: 132,669,868 (GRCm39)	D314G	probably benign	Het
Mga	T	A	2: 119,733,393 (GRCm39)	D80E	probably damaging	Het
Msh4	A	G	3: 153,563,144 (GRCm39)	L744P	probably damaging	Het
Myof	A	T	19: 37,968,871 (GRCm39)	L348*	probably null	Het
Or12j3	T	A	7: 139,953,038 (GRCm39)	M162L	probably benign	Het
Or6z1	T	C	7: 6,504,899 (GRCm39)	I109V	probably benign	Het
Otud3	T	C	4: 138,624,208 (GRCm39)	D278G	probably benign	Het
Pdpr	C	A	8: 111,856,288 (GRCm39)	H670Q	probably damaging	Het
Phf21b	C	A	15: 84,692,262 (GRCm39)		probably benign	Het
Polr3a	G	A	14: 24,534,188 (GRCm39)	Q106*	probably null	Het
Ptprm	G	T	17: 66,992,618 (GRCm39)	N1366K	probably damaging	Het
Slc10a5	G	A	3: 10,400,259 (GRCm39)	P134S	probably benign	Het
Slc30a9	A	G	5: 67,503,581 (GRCm39)		probably benign	Het
Stat6	T	A	10: 127,493,096 (GRCm39)	V576D	probably damaging	Het
Tmem132d	T	C	5: 128,061,379 (GRCm39)	I408V	probably benign	Het
Tmem50a	T	C	4: 134,625,758 (GRCm39)	E153G	probably damaging	Het
Tmod4	A	G	3: 95,032,929 (GRCm39)	T22A	probably benign	Het
Tmprss7	C	T	16: 45,500,997 (GRCm39)	G268D	probably damaging	Het
Tor1a	A	G	2: 30,853,715 (GRCm39)		probably null	Het
Trarg1	G	A	11: 76,571,292 (GRCm39)	V103I	probably benign	Het
Ttc29	T	C	8: 79,008,970 (GRCm39)	L280P	probably damaging	Het
Usp20	A	G	2: 30,907,175 (GRCm39)	E594G	probably benign	Het
Vmn1r31	A	C	6: 58,449,709 (GRCm39)	M3R	possibly damaging	Het

Other mutations in Clec2e

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02529:Clec2e	APN	6	129,075,459 (GRCm39)	splice site	probably benign
IGL03242:Clec2e	APN	6	129,071,989 (GRCm39)	missense	probably damaging	1.00
IGL03289:Clec2e	APN	6	129,075,418 (GRCm39)	missense	probably damaging	0.97
R0090:Clec2e	UTSW	6	129,072,181 (GRCm39)	splice site	probably null
R0390:Clec2e	UTSW	6	129,070,431 (GRCm39)	missense	probably damaging	0.99
R1468:Clec2e	UTSW	6	129,070,459 (GRCm39)	nonsense	probably null
R1468:Clec2e	UTSW	6	129,070,459 (GRCm39)	nonsense	probably null
R1477:Clec2e	UTSW	6	129,072,163 (GRCm39)	missense	probably benign	0.03
R3721:Clec2e	UTSW	6	129,071,373 (GRCm39)	nonsense	probably null
R4769:Clec2e	UTSW	6	129,077,790 (GRCm39)	missense	probably benign	0.08
R5589:Clec2e	UTSW	6	129,075,391 (GRCm39)	missense	probably benign	0.01
R6056:Clec2e	UTSW	6	129,077,772 (GRCm39)	missense	probably benign	0.00
R6156:Clec2e	UTSW	6	129,072,061 (GRCm39)	missense	possibly damaging	0.94
R7762:Clec2e	UTSW	6	129,072,091 (GRCm39)	missense	possibly damaging	0.92
R8024:Clec2e	UTSW	6	129,071,388 (GRCm39)	missense	possibly damaging	0.83
R8973:Clec2e	UTSW	6	129,070,374 (GRCm39)	nonsense	probably null
R9299:Clec2e	UTSW	6	129,072,092 (GRCm39)	missense	probably benign	0.24
R9420:Clec2e	UTSW	6	129,071,420 (GRCm39)	missense	possibly damaging	0.90
R9644:Clec2e	UTSW	6	129,070,443 (GRCm39)	missense	probably benign	0.02

Posted On

2014-02-04