Incidental Mutation 'IGL00161:Vmn1r64'
ID1538
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r64
Ensembl Gene ENSMUSG00000058399
Gene Namevomeronasal 1 receptor 64
SynonymsV1rd11
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.058) question?
Stock #IGL00161
Quality Score
Status
Chromosome7
Chromosomal Location5883580-5884590 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to C at 5883828 bp
ZygosityHeterozygous
Amino Acid Change Threonine to Alanine at position 239 (T239A)
Ref Sequence ENSEMBL: ENSMUSP00000077568 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000078475]
Predicted Effect probably damaging
Transcript: ENSMUST00000078475
AA Change: T239A

PolyPhen 2 Score 0.981 (Sensitivity: 0.75; Specificity: 0.96)
SMART Domains Protein: ENSMUSP00000077568
Gene: ENSMUSG00000058399
AA Change: T239A

DomainStartEndE-ValueType
Pfam:TAS2R 8 296 3.3e-13 PFAM
Pfam:V1R 41 296 1.5e-19 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 27 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700022I11Rik A T 4: 42,973,982 H1105L probably benign Het
4930467E23Rik T C 8: 19,749,483 probably benign Het
Akap13 T A 7: 75,725,971 V1932E probably damaging Het
Alg3 A G 16: 20,607,858 V211A probably damaging Het
Bsn T C 9: 108,115,110 T1148A probably benign Het
Dmbt1 G T 7: 131,109,628 D1538Y probably damaging Het
Fbxl20 C T 11: 98,090,674 G396D possibly damaging Het
Gsto2 A G 19: 47,874,967 D94G probably damaging Het
Igf2r T C 17: 12,713,990 I882V probably benign Het
Ltbp1 C T 17: 75,310,152 probably benign Het
Men1 G A 19: 6,337,207 probably null Het
Nlrp1b A C 11: 71,181,181 probably benign Het
Notch3 A T 17: 32,158,114 C272* probably null Het
Olfr1230 A G 2: 89,296,455 C272R probably benign Het
Olfr943 A G 9: 39,185,092 K305E possibly damaging Het
Pard3 A G 8: 127,359,818 probably benign Het
Pcsk4 A G 10: 80,322,823 Y532H probably damaging Het
Pkd1l1 A G 11: 8,929,353 probably null Het
Prex1 A G 2: 166,638,401 Y140H probably damaging Het
Ptpdc1 C T 13: 48,587,058 R238Q possibly damaging Het
Rdx A G 9: 52,086,346 D540G probably damaging Het
Rnase10 T G 14: 51,009,781 D168E possibly damaging Het
Slc30a5 A C 13: 100,806,666 D561E probably damaging Het
Spag1 C T 15: 36,195,416 R252* probably null Het
Stox1 T C 10: 62,667,913 E121G probably damaging Het
Synm T C 7: 67,734,915 M558V probably benign Het
Tenm2 C T 11: 36,206,899 probably benign Het
Other mutations in Vmn1r64
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01070:Vmn1r64 APN 7 5883942 missense probably benign 0.04
IGL01817:Vmn1r64 APN 7 5884223 missense probably damaging 1.00
IGL02026:Vmn1r64 APN 7 5883650 missense possibly damaging 0.84
IGL02657:Vmn1r64 APN 7 5883728 missense probably benign 0.33
IGL03352:Vmn1r64 APN 7 5884071 missense probably benign 0.12
R0200:Vmn1r64 UTSW 7 5883818 missense probably benign 0.38
R0540:Vmn1r64 UTSW 7 5884097 missense probably damaging 1.00
R0655:Vmn1r64 UTSW 7 5884208 missense probably benign 0.25
R1212:Vmn1r64 UTSW 7 5884211 missense probably damaging 1.00
R1579:Vmn1r64 UTSW 7 5883804 missense probably damaging 1.00
R2034:Vmn1r64 UTSW 7 5883989 missense probably benign 0.09
R2221:Vmn1r64 UTSW 7 5884449 missense probably benign 0.00
R2240:Vmn1r64 UTSW 7 5884370 nonsense probably null
R2305:Vmn1r64 UTSW 7 5884536 missense probably benign 0.04
R3019:Vmn1r64 UTSW 7 5884227 missense probably damaging 1.00
R4256:Vmn1r64 UTSW 7 5883896 missense probably benign 0.05
R4666:Vmn1r64 UTSW 7 5884358 missense probably damaging 0.99
R4996:Vmn1r64 UTSW 7 5884053 missense probably benign 0.03
R5682:Vmn1r64 UTSW 7 5883623 missense possibly damaging 0.79
R5730:Vmn1r64 UTSW 7 5884523 missense probably benign 0.01
R7397:Vmn1r64 UTSW 7 5884014 missense possibly damaging 0.87
X0063:Vmn1r64 UTSW 7 5884350 missense probably benign 0.00
Posted On2011-07-12