Incidental Mutation 'IGL00161:Vmn1r64'
| ID |
1538 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r64
|
| Ensembl Gene |
ENSMUSG00000058399 |
| Gene Name |
vomeronasal 1 receptor 64 |
| Synonyms |
V1rd11 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.053)
|
| Stock # |
IGL00161
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
5886579-5887541 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 5886827 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 239
(T239A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000077568
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000078475]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000078475
AA Change: T239A
PolyPhen 2
Score 0.981 (Sensitivity: 0.75; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000077568
Gene: ENSMUSG00000058399
AA Change: T239A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
8 |
296 |
3.3e-13 |
PFAM |
|
Pfam:V1R
|
41 |
296 |
1.5e-19 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 27 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Akap13 |
T |
A |
7: 75,375,719 (GRCm39) |
V1932E |
probably damaging |
Het |
| Alg3 |
A |
G |
16: 20,426,608 (GRCm39) |
V211A |
probably damaging |
Het |
| Bsn |
T |
C |
9: 107,992,309 (GRCm39) |
T1148A |
probably benign |
Het |
| Dmbt1 |
G |
T |
7: 130,711,357 (GRCm39) |
D1538Y |
probably damaging |
Het |
| Fbxl20 |
C |
T |
11: 97,981,500 (GRCm39) |
G396D |
possibly damaging |
Het |
| Gsto2 |
A |
G |
19: 47,863,406 (GRCm39) |
D94G |
probably damaging |
Het |
| Igf2r |
T |
C |
17: 12,932,877 (GRCm39) |
I882V |
probably benign |
Het |
| Ltbp1 |
C |
T |
17: 75,617,147 (GRCm39) |
|
probably benign |
Het |
| Men1 |
G |
A |
19: 6,387,237 (GRCm39) |
|
probably null |
Het |
| Nlrp1b |
A |
C |
11: 71,072,007 (GRCm39) |
|
probably benign |
Het |
| Notch3 |
A |
T |
17: 32,377,088 (GRCm39) |
C272* |
probably null |
Het |
| Or4c123 |
A |
G |
2: 89,126,799 (GRCm39) |
C272R |
probably benign |
Het |
| Or8g26 |
A |
G |
9: 39,096,388 (GRCm39) |
K305E |
possibly damaging |
Het |
| Pard3 |
A |
G |
8: 128,086,299 (GRCm39) |
|
probably benign |
Het |
| Pcsk4 |
A |
G |
10: 80,158,657 (GRCm39) |
Y532H |
probably damaging |
Het |
| Pkd1l1 |
A |
G |
11: 8,879,353 (GRCm39) |
|
probably null |
Het |
| Potefam3e |
T |
C |
8: 19,799,499 (GRCm39) |
|
probably benign |
Het |
| Prex1 |
A |
G |
2: 166,480,321 (GRCm39) |
Y140H |
probably damaging |
Het |
| Ptpdc1 |
C |
T |
13: 48,740,534 (GRCm39) |
R238Q |
possibly damaging |
Het |
| Rdx |
A |
G |
9: 51,997,646 (GRCm39) |
D540G |
probably damaging |
Het |
| Rnase10 |
T |
G |
14: 51,247,238 (GRCm39) |
D168E |
possibly damaging |
Het |
| Slc30a5 |
A |
C |
13: 100,943,174 (GRCm39) |
D561E |
probably damaging |
Het |
| Spag1 |
C |
T |
15: 36,195,562 (GRCm39) |
R252* |
probably null |
Het |
| Spata31g1 |
A |
T |
4: 42,973,982 (GRCm39) |
H1105L |
probably benign |
Het |
| Stox1 |
T |
C |
10: 62,503,692 (GRCm39) |
E121G |
probably damaging |
Het |
| Synm |
T |
C |
7: 67,384,663 (GRCm39) |
M558V |
probably benign |
Het |
| Tenm2 |
C |
T |
11: 36,097,726 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Vmn1r64 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01070:Vmn1r64
|
APN |
7 |
5,886,941 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01817:Vmn1r64
|
APN |
7 |
5,887,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02026:Vmn1r64
|
APN |
7 |
5,886,649 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL02657:Vmn1r64
|
APN |
7 |
5,886,727 (GRCm39) |
missense |
probably benign |
0.33 |
|
IGL03352:Vmn1r64
|
APN |
7 |
5,887,070 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0200:Vmn1r64
|
UTSW |
7 |
5,886,817 (GRCm39) |
missense |
probably benign |
0.38 |
|
R0540:Vmn1r64
|
UTSW |
7 |
5,887,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0655:Vmn1r64
|
UTSW |
7 |
5,887,207 (GRCm39) |
missense |
probably benign |
0.25 |
|
R1212:Vmn1r64
|
UTSW |
7 |
5,887,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1579:Vmn1r64
|
UTSW |
7 |
5,886,803 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2034:Vmn1r64
|
UTSW |
7 |
5,886,988 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2221:Vmn1r64
|
UTSW |
7 |
5,887,448 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2240:Vmn1r64
|
UTSW |
7 |
5,887,369 (GRCm39) |
nonsense |
probably null |
|
|
R2305:Vmn1r64
|
UTSW |
7 |
5,887,535 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3019:Vmn1r64
|
UTSW |
7 |
5,887,226 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4256:Vmn1r64
|
UTSW |
7 |
5,886,895 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4666:Vmn1r64
|
UTSW |
7 |
5,887,357 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4996:Vmn1r64
|
UTSW |
7 |
5,887,052 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5682:Vmn1r64
|
UTSW |
7 |
5,886,622 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5730:Vmn1r64
|
UTSW |
7 |
5,887,522 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7397:Vmn1r64
|
UTSW |
7 |
5,887,013 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R9697:Vmn1r64
|
UTSW |
7 |
5,886,859 (GRCm39) |
missense |
probably benign |
0.04 |
|
X0063:Vmn1r64
|
UTSW |
7 |
5,887,349 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Posted On |
2011-07-12 |
Incidental Mutation