Incidental Mutation 'IGL01776:Naxd'
ID153874
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Naxd
Ensembl Gene ENSMUSG00000031505
Gene NameNAD(P)HX dehydratase
Synonyms0710008K08Rik, Carkd, 2810407E01Rik
Accession Numbers
Is this an essential gene? Possibly non essential (E-score: 0.407) question?
Stock #IGL01776
Quality Score
Status
Chromosome8
Chromosomal Location11497506-11514960 bp(+) (GRCm38)
Type of Mutationsplice site (6 bp from exon)
DNA Base Change (assembly) T to C at 11505525 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000136535 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000033901] [ENSMUST00000177955] [ENSMUST00000178721] [ENSMUST00000178817]
Predicted Effect probably null
Transcript: ENSMUST00000033901
SMART Domains Protein: ENSMUSP00000033901
Gene: ENSMUSG00000031505

DomainStartEndE-ValueType
transmembrane domain 24 46 N/A INTRINSIC
Pfam:Carb_kinase 94 356 6.2e-63 PFAM
Predicted Effect probably null
Transcript: ENSMUST00000177955
SMART Domains Protein: ENSMUSP00000136363
Gene: ENSMUSG00000031505

DomainStartEndE-ValueType
Pfam:Carb_kinase 56 319 2.5e-62 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000178364
Predicted Effect noncoding transcript
Transcript: ENSMUST00000178382
Predicted Effect probably null
Transcript: ENSMUST00000178721
SMART Domains Protein: ENSMUSP00000136535
Gene: ENSMUSG00000031505

DomainStartEndE-ValueType
Pfam:Carb_kinase 56 242 1.4e-47 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000178817
SMART Domains Protein: ENSMUSP00000137488
Gene: ENSMUSG00000031505

DomainStartEndE-ValueType
Pfam:Carb_kinase 56 79 1.6e-8 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000180269
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 23 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ankrd17 G A 5: 90,283,364 Q854* probably null Het
Armc8 A G 9: 99,526,883 probably benign Het
Chrna7 A G 7: 63,099,519 V405A probably benign Het
Col8a2 C A 4: 126,309,805 probably benign Het
Dcn A G 10: 97,495,076 I91V possibly damaging Het
Dock7 T A 4: 98,940,941 R2069S possibly damaging Het
Gm7247 A G 14: 51,521,899 S112G possibly damaging Het
Hmcn1 T G 1: 150,672,038 T2721P possibly damaging Het
Hsd3b3 T C 3: 98,743,847 T96A probably benign Het
Ifi207 G A 1: 173,725,044 L936F probably damaging Het
Kcp G A 6: 29,497,908 P477S probably damaging Het
Mei1 T C 15: 82,095,932 probably null Het
Mgmt T A 7: 137,121,564 L121* probably null Het
Mrps35 G A 6: 147,070,716 V286I probably benign Het
Pam A G 1: 97,885,600 probably null Het
Plcxd1 G A 5: 110,101,380 probably benign Het
Rasgrp1 A G 2: 117,286,840 probably null Het
Spag9 C T 11: 94,116,727 probably benign Het
Spire2 T C 8: 123,359,392 S288P probably damaging Het
Stk11ip T C 1: 75,527,821 V322A probably benign Het
Syt17 A C 7: 118,409,953 L343R probably damaging Het
Tap1 G A 17: 34,193,128 V436I possibly damaging Het
Virma C T 4: 11,527,792 R1228C probably damaging Het
Other mutations in Naxd
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01983:Naxd APN 8 11510218 unclassified probably benign
R0496:Naxd UTSW 8 11510224 unclassified probably benign
R2044:Naxd UTSW 8 11509510 missense probably benign 0.02
R4183:Naxd UTSW 8 11502757 missense probably damaging 0.97
R4618:Naxd UTSW 8 11509489 missense probably damaging 0.98
R5015:Naxd UTSW 8 11513032 missense probably damaging 1.00
R5636:Naxd UTSW 8 11502676 missense probably benign 0.02
R6947:Naxd UTSW 8 11502757 missense probably damaging 0.97
R7121:Naxd UTSW 8 11506745 missense probably damaging 1.00
Posted On2014-02-04