Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL01782:Vmn1r73'

153967

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r73

Ensembl Gene

ENSMUSG00000051687

Gene Name

vomeronasal 1 receptor 73

Synonyms

V1rg2

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.067) question?

Stock #

IGL01782

Quality Score

Status

Chromosome

Chromosomal Location

11730266-11762081 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 11756738 bp

Zygosity

Heterozygous

Amino Acid Change

Lysine to Arginine at position 161 (K161R)

Ref Sequence

ENSEMBL: ENSMUSP00000153827 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000055070] [ENSMUST00000226516]

Predicted Effect

probably benign
Transcript: ENSMUST00000055070
AA Change: K161R

PolyPhen 2 Score 0.021 (Sensitivity: 0.95; Specificity: 0.80)

SMART Domains

Protein: ENSMUSP00000055353
Gene: ENSMUSG00000051687
AA Change: K161R

Domain	Start	End	E-Value	Type
Pfam:TAS2R	1	301	7.5e-7	PFAM
Pfam:V1R	32	297	1.9e-27	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000226516
AA Change: K161R

PolyPhen 2 Score 0.021 (Sensitivity: 0.95; Specificity: 0.80)

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 40 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aagab	T	C	9: 63,616,713	V34A	probably benign	Het
Acacb	G	T	5: 114,200,520	G764W	probably damaging	Het
Ankib1	A	G	5: 3,727,607	C428R	probably damaging	Het
Card11	A	G	5: 140,927,726	M1T	probably null	Het
Ccdc62	T	A	5: 123,954,576	N541K	possibly damaging	Het
Cep290	C	T	10: 100,545,125	Q1742*	probably null	Het
Cyp2c23	T	C	19: 44,029,115	T25A	possibly damaging	Het
Dtx2	C	A	5: 136,010,127	Y13*	probably null	Het
Dync1h1	T	C	12: 110,614,940	I273T	probably damaging	Het
E430018J23Rik	T	C	7: 127,393,304	T45A	probably benign	Het
Etfb	A	G	7: 43,454,542	T134A	probably damaging	Het
Fig4	A	C	10: 41,270,400	L182R	probably benign	Het
Gm10220	A	T	5: 26,117,023	L217Q	probably damaging	Het
Gm4871	T	G	5: 145,030,360		probably benign	Het
Gm5346	T	A	8: 43,626,735	T151S	probably benign	Het
Gm5464	T	C	14: 66,869,388		probably benign	Het
Lurap1	A	G	4: 116,144,503		probably benign	Het
Mmp17	T	A	5: 129,602,141	V368E	probably damaging	Het
Mrpl22	T	A	11: 58,171,844		probably null	Het
Nisch	G	A	14: 31,176,639		probably benign	Het
Odf4	A	T	11: 68,926,633	H76Q	probably damaging	Het
Olfr330	T	A	11: 58,529,159	M276L	probably benign	Het
Olfr777	C	T	10: 129,269,039	V95I	probably benign	Het
Orc1	T	C	4: 108,606,268	S661P	possibly damaging	Het
Otud4	T	G	8: 79,673,011	F784V	possibly damaging	Het
Prkch	A	G	12: 73,759,662	D561G	probably damaging	Het
Pttg1ip	T	C	10: 77,581,929		probably null	Het
Ranbp2	A	G	10: 58,478,309	K1617R	probably damaging	Het
Rarb	T	G	14: 16,434,180	S333R	probably damaging	Het
Rps6ka2	A	G	17: 7,236,124	K99E	probably benign	Het
Sel1l2	A	T	2: 140,243,935	W542R	probably damaging	Het
Sema3g	G	T	14: 31,227,791	R643L	probably damaging	Het
Sltm	T	A	9: 70,573,641	D258E	probably damaging	Het
Stx18	G	A	5: 38,106,611	V80I	possibly damaging	Het
Taar2	A	T	10: 23,941,144	N194I	probably damaging	Het
Ube2r2	T	C	4: 41,174,129		probably null	Het
Unk	C	A	11: 116,058,379	N645K	probably benign	Het
Vps13a	T	C	19: 16,754,337	D137G	probably damaging	Het
Xrra1	A	G	7: 99,875,194	T104A	possibly damaging	Het
Zfp410	T	A	12: 84,327,274		probably benign	Het

Other mutations in Vmn1r73

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02337:Vmn1r73	APN	7	11756713	missense	possibly damaging	0.69
IGL02666:Vmn1r73	APN	7	11756938	missense	probably damaging	1.00
IGL02741:Vmn1r73	APN	7	11756783	missense	probably benign	0.05
IGL02756:Vmn1r73	APN	7	11756647	missense	possibly damaging	0.95
IGL03113:Vmn1r73	APN	7	11756600	missense	probably benign
IGL03195:Vmn1r73	APN	7	11757080	missense	probably damaging	1.00
R0023:Vmn1r73	UTSW	7	11757070	missense	probably benign	0.43
R0379:Vmn1r73	UTSW	7	11756846	missense	probably benign	0.16
R3941:Vmn1r73	UTSW	7	11756755	missense	probably damaging	1.00
R4224:Vmn1r73	UTSW	7	11756579	missense	probably damaging	0.99
R4631:Vmn1r73	UTSW	7	11756831	missense	probably benign	0.22
R4912:Vmn1r73	UTSW	7	11756669	missense	probably damaging	0.99
R5060:Vmn1r73	UTSW	7	11756756	missense	probably damaging	1.00
R5450:Vmn1r73	UTSW	7	11756449	missense	possibly damaging	0.63
R5609:Vmn1r73	UTSW	7	11756664	nonsense	probably null
R6059:Vmn1r73	UTSW	7	11756611	missense	probably benign	0.40
R6508:Vmn1r73	UTSW	7	11756704	missense	possibly damaging	0.73
R6967:Vmn1r73	UTSW	7	11756617	nonsense	probably null
R7099:Vmn1r73	UTSW	7	11756393	missense	probably damaging	1.00
R7304:Vmn1r73	UTSW	7	11756897	missense	probably damaging	1.00
R7579:Vmn1r73	UTSW	7	11757155	missense	probably benign	0.08
R7891:Vmn1r73	UTSW	7	11757109	missense	possibly damaging	0.87
Z1176:Vmn1r73	UTSW	7	11756956	missense	probably benign	0.02

Posted On

2014-02-04