Incidental Mutation 'IGL01782:Zfp410'
| ID |
153979 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Zfp410
|
| Ensembl Gene |
ENSMUSG00000042472 |
| Gene Name |
zinc finger protein 410 |
| Synonyms |
D12Ertd748e |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.197)
|
| Stock # |
IGL01782
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
12 |
| Chromosomal Location |
84363626-84390497 bp(+) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
T to A
at 84374048 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000152817
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000045931]
[ENSMUST00000220931]
[ENSMUST00000221656]
[ENSMUST00000222258]
[ENSMUST00000222606]
[ENSMUST00000222832]
[ENSMUST00000222471]
|
| AlphaFold |
Q8BKX7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000045931
|
| SMART Domains |
Protein: ENSMUSP00000045550
Gene: ENSMUSG00000042472
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
219 |
243 |
1.04e-3 |
SMART |
|
ZnF_C2H2
|
249 |
273 |
6.88e-4 |
SMART |
|
ZnF_C2H2
|
279 |
303 |
1.13e-4 |
SMART |
|
ZnF_C2H2
|
309 |
333 |
1.45e-2 |
SMART |
|
ZnF_C2H2
|
339 |
361 |
5.59e-4 |
SMART |
|
low complexity region
|
400 |
417 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000220931
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000220955
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000221490
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000221656
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000222258
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000222431
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000222606
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000222773
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000222832
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000222450
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000222471
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 40 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aagab |
T |
C |
9: 63,523,995 (GRCm39) |
V34A |
probably benign |
Het |
| Acacb |
G |
T |
5: 114,338,581 (GRCm39) |
G764W |
probably damaging |
Het |
| Adam34l |
T |
A |
8: 44,079,772 (GRCm39) |
T151S |
probably benign |
Het |
| Ankib1 |
A |
G |
5: 3,777,607 (GRCm39) |
C428R |
probably damaging |
Het |
| Card11 |
A |
G |
5: 140,913,481 (GRCm39) |
M1T |
probably null |
Het |
| Ccdc62 |
T |
A |
5: 124,092,639 (GRCm39) |
N541K |
possibly damaging |
Het |
| Cep290 |
C |
T |
10: 100,380,987 (GRCm39) |
Q1742* |
probably null |
Het |
| Cyp2c23 |
T |
C |
19: 44,017,554 (GRCm39) |
T25A |
possibly damaging |
Het |
| Dtx2 |
C |
A |
5: 136,038,981 (GRCm39) |
Y13* |
probably null |
Het |
| Dync1h1 |
T |
C |
12: 110,581,374 (GRCm39) |
I273T |
probably damaging |
Het |
| Etfb |
A |
G |
7: 43,103,966 (GRCm39) |
T134A |
probably damaging |
Het |
| Fig4 |
A |
C |
10: 41,146,396 (GRCm39) |
L182R |
probably benign |
Het |
| Gm10220 |
A |
T |
5: 26,322,021 (GRCm39) |
L217Q |
probably damaging |
Het |
| Gm4871 |
T |
G |
5: 144,967,170 (GRCm39) |
|
probably benign |
Het |
| Gm5464 |
T |
C |
14: 67,106,837 (GRCm39) |
|
probably benign |
Het |
| Lurap1 |
A |
G |
4: 116,001,700 (GRCm39) |
|
probably benign |
Het |
| Mmp17 |
T |
A |
5: 129,679,205 (GRCm39) |
V368E |
probably damaging |
Het |
| Mrpl22 |
T |
A |
11: 58,062,670 (GRCm39) |
|
probably null |
Het |
| Nisch |
G |
A |
14: 30,898,596 (GRCm39) |
|
probably benign |
Het |
| Odf4 |
A |
T |
11: 68,817,459 (GRCm39) |
H76Q |
probably damaging |
Het |
| Or2t48 |
T |
A |
11: 58,419,985 (GRCm39) |
M276L |
probably benign |
Het |
| Or6c207 |
C |
T |
10: 129,104,908 (GRCm39) |
V95I |
probably benign |
Het |
| Orc1 |
T |
C |
4: 108,463,465 (GRCm39) |
S661P |
possibly damaging |
Het |
| Otud4 |
T |
G |
8: 80,399,640 (GRCm39) |
F784V |
possibly damaging |
Het |
| Prkch |
A |
G |
12: 73,806,436 (GRCm39) |
D561G |
probably damaging |
Het |
| Pttg1ip |
T |
C |
10: 77,417,763 (GRCm39) |
|
probably null |
Het |
| Ranbp2 |
A |
G |
10: 58,314,131 (GRCm39) |
K1617R |
probably damaging |
Het |
| Rarb |
T |
G |
14: 16,434,180 (GRCm38) |
S333R |
probably damaging |
Het |
| Rps6ka2 |
A |
G |
17: 7,503,523 (GRCm39) |
K99E |
probably benign |
Het |
| Sel1l2 |
A |
T |
2: 140,085,855 (GRCm39) |
W542R |
probably damaging |
Het |
| Sema3g |
G |
T |
14: 30,949,748 (GRCm39) |
R643L |
probably damaging |
Het |
| Sltm |
T |
A |
9: 70,480,923 (GRCm39) |
D258E |
probably damaging |
Het |
| Stx18 |
G |
A |
5: 38,263,955 (GRCm39) |
V80I |
possibly damaging |
Het |
| Taar2 |
A |
T |
10: 23,817,042 (GRCm39) |
N194I |
probably damaging |
Het |
| Ube2r2 |
T |
C |
4: 41,174,129 (GRCm39) |
|
probably null |
Het |
| Unk |
C |
A |
11: 115,949,205 (GRCm39) |
N645K |
probably benign |
Het |
| Vmn1r73 |
A |
G |
7: 11,490,665 (GRCm39) |
K161R |
probably benign |
Het |
| Vps13a |
T |
C |
19: 16,731,701 (GRCm39) |
D137G |
probably damaging |
Het |
| Xrra1 |
A |
G |
7: 99,524,401 (GRCm39) |
T104A |
possibly damaging |
Het |
| Zfp764l1 |
T |
C |
7: 126,992,476 (GRCm39) |
T45A |
probably benign |
Het |
|
| Other mutations in Zfp410 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01871:Zfp410
|
APN |
12 |
84,372,565 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02152:Zfp410
|
APN |
12 |
84,379,702 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02702:Zfp410
|
APN |
12 |
84,372,550 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02902:Zfp410
|
APN |
12 |
84,378,594 (GRCm39) |
splice site |
probably null |
|
|
R0453:Zfp410
|
UTSW |
12 |
84,378,486 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1525:Zfp410
|
UTSW |
12 |
84,369,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1569:Zfp410
|
UTSW |
12 |
84,379,726 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1694:Zfp410
|
UTSW |
12 |
84,372,494 (GRCm39) |
missense |
probably benign |
|
|
R2263:Zfp410
|
UTSW |
12 |
84,369,794 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2878:Zfp410
|
UTSW |
12 |
84,378,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3941:Zfp410
|
UTSW |
12 |
84,385,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4155:Zfp410
|
UTSW |
12 |
84,374,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4156:Zfp410
|
UTSW |
12 |
84,374,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4157:Zfp410
|
UTSW |
12 |
84,374,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4630:Zfp410
|
UTSW |
12 |
84,372,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4632:Zfp410
|
UTSW |
12 |
84,372,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4633:Zfp410
|
UTSW |
12 |
84,372,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4880:Zfp410
|
UTSW |
12 |
84,384,449 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4969:Zfp410
|
UTSW |
12 |
84,378,582 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5893:Zfp410
|
UTSW |
12 |
84,384,385 (GRCm39) |
splice site |
probably null |
|
|
R5981:Zfp410
|
UTSW |
12 |
84,378,414 (GRCm39) |
missense |
probably benign |
0.17 |
|
R6268:Zfp410
|
UTSW |
12 |
84,378,612 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7318:Zfp410
|
UTSW |
12 |
84,372,464 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7599:Zfp410
|
UTSW |
12 |
84,378,630 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8357:Zfp410
|
UTSW |
12 |
84,374,086 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8457:Zfp410
|
UTSW |
12 |
84,374,086 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
| Posted On |
2014-02-04 |
Incidental Mutation