Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01784:Mphosph9'

154259

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Mphosph9

Ensembl Gene

ENSMUSG00000038126

Gene Name

M-phase phosphoprotein 9

Synonyms

4930548D04Rik, MPP9, B930097C17Rik, 9630025B04Rik, MPP-9

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL01784

Quality Score

Status

Chromosome

Chromosomal Location

124389022-124466001 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

T to C at 124403373 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000138982 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000031344] [ENSMUST00000147737] [ENSMUST00000184951]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000031344

SMART Domains

Protein: ENSMUSP00000031344
Gene: ENSMUSG00000038126

Domain	Start	End	E-Value	Type
low complexity region	102	119	N/A	INTRINSIC
low complexity region	128	140	N/A	INTRINSIC
low complexity region	414	428	N/A	INTRINSIC
coiled coil region	574	736	N/A	INTRINSIC
low complexity region	879	898	N/A	INTRINSIC
low complexity region	957	971	N/A	INTRINSIC
coiled coil region	1040	1105	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000128027

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000142498

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000143476

Predicted Effect

probably benign
Transcript: ENSMUST00000147737

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000156745

Predicted Effect

probably benign
Transcript: ENSMUST00000184951

SMART Domains

Protein: ENSMUSP00000138982
Gene: ENSMUSG00000038126

Domain	Start	End	E-Value	Type
coiled coil region	102	130	N/A	INTRINSIC
low complexity region	132	149	N/A	INTRINSIC
low complexity region	158	170	N/A	INTRINSIC
low complexity region	444	458	N/A	INTRINSIC
coiled coil region	604	766	N/A	INTRINSIC
low complexity region	909	928	N/A	INTRINSIC
low complexity region	987	1001	N/A	INTRINSIC
coiled coil region	1070	1135	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 38 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2810021J22Rik	C	T	11: 58,771,445 (GRCm39)	P309L	possibly damaging	Het
Abca4	A	T	3: 121,932,154 (GRCm39)	K269N	probably benign	Het
Abcb5	T	C	12: 118,854,399 (GRCm39)	T839A	probably benign	Het
Adcy7	A	G	8: 89,040,751 (GRCm39)	D30G	probably damaging	Het
Aldh3b1	A	G	19: 3,971,217 (GRCm39)	I149T	probably benign	Het
Ap3b1	A	G	13: 94,630,247 (GRCm39)	D199G	probably damaging	Het
Cplx3	T	C	9: 57,527,847 (GRCm39)	Y36C	probably damaging	Het
Ddo	A	G	10: 40,507,784 (GRCm39)		probably benign	Het
Ensa	T	A	3: 95,535,844 (GRCm39)		probably benign	Het
Etnppl	A	G	3: 130,425,427 (GRCm39)	I405V	possibly damaging	Het
Fam171b	T	A	2: 83,710,031 (GRCm39)	L568M	possibly damaging	Het
Fmn2	A	G	1: 174,329,994 (GRCm39)	D128G	unknown	Het
Fra10ac1	T	A	19: 38,208,125 (GRCm39)	H43L	probably benign	Het
Gm7589	T	C	9: 59,053,310 (GRCm39)		noncoding transcript	Het
Gsx1	A	G	5: 147,126,939 (GRCm39)	D254G	probably benign	Het
Hoxb6	A	G	11: 96,191,639 (GRCm39)	E187G	probably damaging	Het
Kmt2c	A	T	5: 25,518,524 (GRCm39)	I2385N	probably damaging	Het
Mc3r	T	A	2: 172,091,290 (GRCm39)	C171S	probably benign	Het
Mccc1	T	G	3: 36,030,897 (GRCm39)	N390H	probably damaging	Het
Nfic	T	C	10: 81,241,982 (GRCm39)	D364G	possibly damaging	Het
Niban1	T	A	1: 151,525,116 (GRCm39)	Y174N	probably damaging	Het
Npy	A	G	6: 49,806,314 (GRCm39)		probably benign	Het
Or6c8	C	T	10: 128,915,224 (GRCm39)	V203M	probably benign	Het
Osbpl3	A	G	6: 50,321,902 (GRCm39)	S75P	probably damaging	Het
Plekhg4	G	T	8: 106,105,589 (GRCm39)	A685S	probably damaging	Het
Pramel51	A	G	12: 88,143,085 (GRCm39)	Y178H	probably benign	Het
Prss53	T	C	7: 127,485,724 (GRCm39)	T539A	probably benign	Het
Rnf43	T	A	11: 87,622,632 (GRCm39)	S537T	possibly damaging	Het
Rpgrip1l	G	A	8: 91,997,089 (GRCm39)	T597I	possibly damaging	Het
Rtn4	C	A	11: 29,657,291 (GRCm39)	Q482K	probably damaging	Het
Sema3g	T	C	14: 30,944,924 (GRCm39)	I349T	probably damaging	Het
Sh3gl1	A	C	17: 56,326,325 (GRCm39)	S108A	possibly damaging	Het
Tmc7	A	T	7: 118,146,538 (GRCm39)		probably null	Het
Tmem131	G	A	1: 36,854,564 (GRCm39)	T131I	probably damaging	Het
Vac14	T	C	8: 111,397,800 (GRCm39)	L505P	probably benign	Het
Wasf2	A	G	4: 132,919,439 (GRCm39)	Q231R	unknown	Het
Wnt7a	A	G	6: 91,342,839 (GRCm39)	C348R	probably damaging	Het
Zkscan6	T	A	11: 65,705,547 (GRCm39)	L86Q	probably damaging	Het

Other mutations in Mphosph9

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01363:Mphosph9	APN	5	124,400,084 (GRCm39)	missense	probably damaging	1.00
IGL01527:Mphosph9	APN	5	124,421,687 (GRCm39)	splice site	probably benign
IGL01958:Mphosph9	APN	5	124,463,053 (GRCm39)	utr 5 prime	probably benign
IGL02020:Mphosph9	APN	5	124,397,013 (GRCm39)	missense	probably damaging	0.99
IGL02190:Mphosph9	APN	5	124,403,488 (GRCm39)	missense	possibly damaging	0.92
IGL02261:Mphosph9	APN	5	124,398,150 (GRCm39)	missense	probably damaging	1.00
IGL02569:Mphosph9	APN	5	124,435,634 (GRCm39)	nonsense	probably null
IGL02640:Mphosph9	APN	5	124,453,563 (GRCm39)	missense	possibly damaging	0.66
IGL02702:Mphosph9	APN	5	124,398,052 (GRCm39)	missense	probably damaging	1.00
IGL02793:Mphosph9	APN	5	124,421,800 (GRCm39)	critical splice acceptor site	probably null
IGL02813:Mphosph9	APN	5	124,453,691 (GRCm39)	missense	probably benign	0.37
IGL02875:Mphosph9	APN	5	124,421,800 (GRCm39)	critical splice acceptor site	probably null
IGL03149:Mphosph9	APN	5	124,401,074 (GRCm39)	missense	probably damaging	1.00
PIT4445001:Mphosph9	UTSW	5	124,436,853 (GRCm39)	missense	possibly damaging	0.82
R0304:Mphosph9	UTSW	5	124,436,892 (GRCm39)	missense	probably benign	0.01
R0437:Mphosph9	UTSW	5	124,453,631 (GRCm39)	missense	probably benign	0.27
R0483:Mphosph9	UTSW	5	124,445,033 (GRCm39)	nonsense	probably null
R0811:Mphosph9	UTSW	5	124,436,822 (GRCm39)	missense	probably damaging	1.00
R0812:Mphosph9	UTSW	5	124,436,822 (GRCm39)	missense	probably damaging	1.00
R0942:Mphosph9	UTSW	5	124,400,100 (GRCm39)	nonsense	probably null
R1175:Mphosph9	UTSW	5	124,453,739 (GRCm39)	missense	possibly damaging	0.94
R1372:Mphosph9	UTSW	5	124,421,808 (GRCm39)	splice site	probably null
R1442:Mphosph9	UTSW	5	124,403,461 (GRCm39)	missense	possibly damaging	0.62
R1533:Mphosph9	UTSW	5	124,405,204 (GRCm39)	missense	probably damaging	1.00
R1959:Mphosph9	UTSW	5	124,453,764 (GRCm39)	missense	possibly damaging	0.92
R2036:Mphosph9	UTSW	5	124,442,274 (GRCm39)	missense	probably damaging	0.97
R2256:Mphosph9	UTSW	5	124,421,722 (GRCm39)	missense	probably benign	0.00
R2919:Mphosph9	UTSW	5	124,399,069 (GRCm39)	missense	probably benign	0.22
R2920:Mphosph9	UTSW	5	124,399,069 (GRCm39)	missense	probably benign	0.22
R4064:Mphosph9	UTSW	5	124,428,980 (GRCm39)	missense	probably damaging	1.00
R4272:Mphosph9	UTSW	5	124,442,266 (GRCm39)	missense	probably damaging	0.96
R4430:Mphosph9	UTSW	5	124,403,509 (GRCm39)	missense	possibly damaging	0.83
R4883:Mphosph9	UTSW	5	124,437,108 (GRCm39)	missense	probably damaging	1.00
R4992:Mphosph9	UTSW	5	124,442,253 (GRCm39)	missense	probably damaging	1.00
R5815:Mphosph9	UTSW	5	124,453,481 (GRCm39)	missense	probably damaging	1.00
R5993:Mphosph9	UTSW	5	124,454,161 (GRCm39)	missense	probably benign	0.40
R6102:Mphosph9	UTSW	5	124,435,772 (GRCm39)	missense	possibly damaging	0.86
R6295:Mphosph9	UTSW	5	124,458,978 (GRCm39)	missense	possibly damaging	0.46
R6320:Mphosph9	UTSW	5	124,463,024 (GRCm39)	missense	probably damaging	0.99
R6628:Mphosph9	UTSW	5	124,436,825 (GRCm39)	missense	probably damaging	0.98
R6692:Mphosph9	UTSW	5	124,398,179 (GRCm39)	missense	probably damaging	1.00
R6705:Mphosph9	UTSW	5	124,429,027 (GRCm39)	missense	possibly damaging	0.83
R6747:Mphosph9	UTSW	5	124,435,762 (GRCm39)	missense	possibly damaging	0.93
R6787:Mphosph9	UTSW	5	124,399,090 (GRCm39)	missense	probably damaging	0.99
R6850:Mphosph9	UTSW	5	124,399,019 (GRCm39)	missense	probably damaging	1.00
R6956:Mphosph9	UTSW	5	124,435,621 (GRCm39)	missense	probably damaging	1.00
R7075:Mphosph9	UTSW	5	124,458,922 (GRCm39)	missense	probably damaging	0.99
R7604:Mphosph9	UTSW	5	124,454,180 (GRCm39)	missense	probably benign	0.01
R7789:Mphosph9	UTSW	5	124,453,650 (GRCm39)	missense	probably damaging	1.00
R7808:Mphosph9	UTSW	5	124,399,009 (GRCm39)	missense	probably damaging	0.99
R7823:Mphosph9	UTSW	5	124,442,319 (GRCm39)	missense	probably damaging	0.99
R7891:Mphosph9	UTSW	5	124,428,967 (GRCm39)	missense	probably damaging	1.00
R8210:Mphosph9	UTSW	5	124,405,174 (GRCm39)	missense	probably damaging	1.00
R8256:Mphosph9	UTSW	5	124,393,169 (GRCm39)	missense	probably damaging	1.00
R8385:Mphosph9	UTSW	5	124,450,785 (GRCm39)	missense	probably benign	0.19
R8438:Mphosph9	UTSW	5	124,430,455 (GRCm39)	missense	probably benign	0.19
R8692:Mphosph9	UTSW	5	124,450,875 (GRCm39)	missense	probably damaging	0.99
R8790:Mphosph9	UTSW	5	124,453,736 (GRCm39)	missense	probably damaging	1.00
R8818:Mphosph9	UTSW	5	124,463,027 (GRCm39)	nonsense	probably null
R8847:Mphosph9	UTSW	5	124,454,209 (GRCm39)	missense	possibly damaging	0.91
R9018:Mphosph9	UTSW	5	124,436,713 (GRCm39)	missense	probably benign	0.12
R9208:Mphosph9	UTSW	5	124,450,854 (GRCm39)	missense	probably damaging	0.97
R9221:Mphosph9	UTSW	5	124,403,427 (GRCm39)	missense	probably benign	0.10
R9603:Mphosph9	UTSW	5	124,463,015 (GRCm39)	nonsense	probably null
R9721:Mphosph9	UTSW	5	124,436,738 (GRCm39)	missense	possibly damaging	0.87

Posted On

2014-02-04