Incidental Mutation 'IGL01813:Vmn1r183'
ID154303
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r183
Ensembl Gene ENSMUSG00000066723
Gene Namevomeronasal 1 receptor 183
SynonymsLOC209824, V1rd15
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.053) question?
Stock #IGL01813
Quality Score
Status
Chromosome7
Chromosomal Location24054774-24055691 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 24055560 bp
ZygosityHeterozygous
Amino Acid Change Phenylalanine to Isoleucine at position 263 (F263I)
Ref Sequence ENSEMBL: ENSMUSP00000083176 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000086012]
Predicted Effect probably benign
Transcript: ENSMUST00000086012
AA Change: F263I

PolyPhen 2 Score 0.192 (Sensitivity: 0.92; Specificity: 0.87)
SMART Domains Protein: ENSMUSP00000083176
Gene: ENSMUSG00000066723
AA Change: F263I

DomainStartEndE-ValueType
Pfam:TAS2R 8 297 5.6e-15 PFAM
Pfam:7tm_1 31 285 1.4e-9 PFAM
Pfam:V1R 41 296 2.5e-18 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000205855
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 32 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4932438A13Rik G A 3: 36,928,520 S778N possibly damaging Het
Abcb11 T A 2: 69,287,592 probably benign Het
Adgrb2 T C 4: 130,012,566 V929A probably benign Het
Aldh2 T C 5: 121,572,073 I400V probably benign Het
Atxn2l T C 7: 126,500,253 D84G probably damaging Het
Avpr1a T A 10: 122,449,011 N69K probably damaging Het
BC022687 C T 12: 112,815,559 T272M probably damaging Het
BC034090 G A 1: 155,226,339 Q60* probably null Het
Bub3 T C 7: 131,568,633 S295P probably benign Het
Cacna1b T C 2: 24,609,890 S161G probably damaging Het
Col6a4 T A 9: 106,077,253 S296C probably damaging Het
Cyp4f15 G A 17: 32,686,157 R38H probably benign Het
Dync2h1 T C 9: 7,122,799 I2052M probably damaging Het
Gm11627 T C 11: 102,578,808 probably benign Het
Jmjd8 A T 17: 25,829,238 probably null Het
Kmt2c A G 5: 25,290,804 V629A possibly damaging Het
Kremen1 T C 11: 5,199,667 T335A probably benign Het
Olfr109 A G 17: 37,466,758 E184G probably damaging Het
Olfr282 A G 15: 98,437,649 Y60C possibly damaging Het
Oosp2 T C 19: 11,651,483 T85A probably benign Het
Pex5l T C 3: 33,082,055 E5G probably benign Het
Pigk A T 3: 152,742,519 Q173L probably damaging Het
Pik3c2g T A 6: 139,622,409 N174K possibly damaging Het
Plb1 C T 5: 32,329,085 H893Y probably damaging Het
Pus7 T C 5: 23,760,304 probably benign Het
R3hdm1 G A 1: 128,175,233 probably null Het
Samd7 C T 3: 30,754,286 P83S probably benign Het
Supt5 T A 7: 28,323,975 Y293F probably damaging Het
Tbc1d30 T C 10: 121,267,051 D692G probably benign Het
Tmpo G A 10: 91,163,242 R228C probably benign Het
Tnn A T 1: 160,088,438 H1236Q probably damaging Het
Ubr3 T C 2: 69,951,570 I667T probably benign Het
Other mutations in Vmn1r183
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00987:Vmn1r183 APN 7 24055224 missense probably damaging 1.00
IGL03377:Vmn1r183 APN 7 24055392 missense possibly damaging 0.70
PIT4791001:Vmn1r183 UTSW 7 24054841 missense probably damaging 0.99
R0463:Vmn1r183 UTSW 7 24055501 missense probably damaging 1.00
R0616:Vmn1r183 UTSW 7 24054825 missense probably benign 0.03
R0666:Vmn1r183 UTSW 7 24055176 missense probably benign
R3928:Vmn1r183 UTSW 7 24055572 missense probably damaging 0.98
R4425:Vmn1r183 UTSW 7 24055548 missense probably benign 0.00
R4767:Vmn1r183 UTSW 7 24055106 frame shift probably null
R4835:Vmn1r183 UTSW 7 24055139 missense probably benign 0.07
R5267:Vmn1r183 UTSW 7 24055546 missense possibly damaging 0.90
R5693:Vmn1r183 UTSW 7 24054802 missense possibly damaging 0.94
R6291:Vmn1r183 UTSW 7 24055557 missense possibly damaging 0.70
R6439:Vmn1r183 UTSW 7 24055279 missense possibly damaging 0.73
R7073:Vmn1r183 UTSW 7 24055501 missense probably damaging 1.00
Posted On2014-02-04