Incidental Mutation 'IGL01817:Vmn1r64'
ID154411
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r64
Ensembl Gene ENSMUSG00000058399
Gene Namevomeronasal 1 receptor 64
SynonymsV1rd11
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.054) question?
Stock #IGL01817
Quality Score
Status
Chromosome7
Chromosomal Location5883580-5884590 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) G to A at 5884223 bp
ZygosityHeterozygous
Amino Acid Change Threonine to Isoleucine at position 107 (T107I)
Ref Sequence ENSEMBL: ENSMUSP00000077568 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000078475]
Predicted Effect probably damaging
Transcript: ENSMUST00000078475
AA Change: T107I

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
SMART Domains Protein: ENSMUSP00000077568
Gene: ENSMUSG00000058399
AA Change: T107I

DomainStartEndE-ValueType
Pfam:TAS2R 8 296 3.3e-13 PFAM
Pfam:V1R 41 296 1.5e-19 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 21 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Eif4g3 T C 4: 138,120,362 V198A probably benign Het
Exoc6b T C 6: 85,069,338 E23G probably damaging Het
Fam46c T C 3: 100,472,855 Y195C probably damaging Het
Gm20390 G T 11: 93,955,621 probably benign Het
Gm4847 C A 1: 166,634,902 D340Y probably damaging Het
Gm5152 C A 5: 10,245,330 A48S probably damaging Het
Gtf3c5 T C 2: 28,569,289 probably null Het
Ighv1-13 G A 12: 114,630,980 probably benign Het
Ighv1-43 C A 12: 114,946,094 E69D probably benign Het
Ighv1-43 T C 12: 114,946,095 E69G probably benign Het
Itln1 C A 1: 171,529,160 L138F probably damaging Het
Nsun5 G T 5: 135,370,039 G19V probably damaging Het
Olfr1223 A G 2: 89,144,358 F222L probably benign Het
Olfr1251 A G 2: 89,667,004 I294T probably benign Het
Olfr632 A G 7: 103,937,823 I148V probably benign Het
Per1 T C 11: 69,104,199 L615P probably damaging Het
Pibf1 C A 14: 99,186,472 probably benign Het
Pik3r4 T A 9: 105,650,822 I458N probably damaging Het
Ppp1r14a T C 7: 29,293,197 V108A probably benign Het
Scamp2 T A 9: 57,581,620 C201* probably null Het
Stambpl1 G T 19: 34,233,993 L151F possibly damaging Het
Other mutations in Vmn1r64
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00161:Vmn1r64 APN 7 5883828 missense probably damaging 0.98
IGL01070:Vmn1r64 APN 7 5883942 missense probably benign 0.04
IGL02026:Vmn1r64 APN 7 5883650 missense possibly damaging 0.84
IGL02657:Vmn1r64 APN 7 5883728 missense probably benign 0.33
IGL03352:Vmn1r64 APN 7 5884071 missense probably benign 0.12
R0200:Vmn1r64 UTSW 7 5883818 missense probably benign 0.38
R0540:Vmn1r64 UTSW 7 5884097 missense probably damaging 1.00
R0655:Vmn1r64 UTSW 7 5884208 missense probably benign 0.25
R1212:Vmn1r64 UTSW 7 5884211 missense probably damaging 1.00
R1579:Vmn1r64 UTSW 7 5883804 missense probably damaging 1.00
R2034:Vmn1r64 UTSW 7 5883989 missense probably benign 0.09
R2221:Vmn1r64 UTSW 7 5884449 missense probably benign 0.00
R2240:Vmn1r64 UTSW 7 5884370 nonsense probably null
R2305:Vmn1r64 UTSW 7 5884536 missense probably benign 0.04
R3019:Vmn1r64 UTSW 7 5884227 missense probably damaging 1.00
R4256:Vmn1r64 UTSW 7 5883896 missense probably benign 0.05
R4666:Vmn1r64 UTSW 7 5884358 missense probably damaging 0.99
R4996:Vmn1r64 UTSW 7 5884053 missense probably benign 0.03
R5682:Vmn1r64 UTSW 7 5883623 missense possibly damaging 0.79
R5730:Vmn1r64 UTSW 7 5884523 missense probably benign 0.01
R7397:Vmn1r64 UTSW 7 5884014 missense possibly damaging 0.87
X0063:Vmn1r64 UTSW 7 5884350 missense probably benign 0.00
Posted On2014-02-04