Incidental Mutation 'IGL01817:Vmn1r64'
| ID |
154411 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r64
|
| Ensembl Gene |
ENSMUSG00000058399 |
| Gene Name |
vomeronasal 1 receptor 64 |
| Synonyms |
V1rd11 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.053)
|
| Stock # |
IGL01817
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
5886579-5887541 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 5887222 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Isoleucine
at position 107
(T107I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000077568
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000078475]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000078475
AA Change: T107I
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000077568
Gene: ENSMUSG00000058399
AA Change: T107I
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
8 |
296 |
3.3e-13 |
PFAM |
|
Pfam:V1R
|
41 |
296 |
1.5e-19 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 21 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Eif4g3 |
T |
C |
4: 137,847,673 (GRCm39) |
V198A |
probably benign |
Het |
| Exoc6b |
T |
C |
6: 85,046,320 (GRCm39) |
E23G |
probably damaging |
Het |
| Gm4847 |
C |
A |
1: 166,462,471 (GRCm39) |
D340Y |
probably damaging |
Het |
| Gtf3c5 |
T |
C |
2: 28,459,301 (GRCm39) |
|
probably null |
Het |
| Ighv1-13 |
G |
A |
12: 114,594,600 (GRCm39) |
|
probably benign |
Het |
| Ighv1-43 |
C |
A |
12: 114,909,714 (GRCm39) |
E69D |
probably benign |
Het |
| Ighv1-43 |
T |
C |
12: 114,909,715 (GRCm39) |
E69G |
probably benign |
Het |
| Itln1 |
C |
A |
1: 171,356,728 (GRCm39) |
L138F |
probably damaging |
Het |
| Nme1nme2 |
G |
T |
11: 93,846,447 (GRCm39) |
|
probably benign |
Het |
| Nsun5 |
G |
T |
5: 135,398,893 (GRCm39) |
G19V |
probably damaging |
Het |
| Or4a78 |
A |
G |
2: 89,497,348 (GRCm39) |
I294T |
probably benign |
Het |
| Or4c118 |
A |
G |
2: 88,974,702 (GRCm39) |
F222L |
probably benign |
Het |
| Or51ai2 |
A |
G |
7: 103,587,030 (GRCm39) |
I148V |
probably benign |
Het |
| Per1 |
T |
C |
11: 68,995,025 (GRCm39) |
L615P |
probably damaging |
Het |
| Pibf1 |
C |
A |
14: 99,423,908 (GRCm39) |
|
probably benign |
Het |
| Pik3r4 |
T |
A |
9: 105,528,021 (GRCm39) |
I458N |
probably damaging |
Het |
| Ppp1r14a |
T |
C |
7: 28,992,622 (GRCm39) |
V108A |
probably benign |
Het |
| Scamp2 |
T |
A |
9: 57,488,903 (GRCm39) |
C201* |
probably null |
Het |
| Speer1c |
C |
A |
5: 10,295,297 (GRCm39) |
A48S |
probably damaging |
Het |
| Stambpl1 |
G |
T |
19: 34,211,393 (GRCm39) |
L151F |
possibly damaging |
Het |
| Tent5c |
T |
C |
3: 100,380,171 (GRCm39) |
Y195C |
probably damaging |
Het |
|
| Other mutations in Vmn1r64 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00161:Vmn1r64
|
APN |
7 |
5,886,827 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01070:Vmn1r64
|
APN |
7 |
5,886,941 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02026:Vmn1r64
|
APN |
7 |
5,886,649 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL02657:Vmn1r64
|
APN |
7 |
5,886,727 (GRCm39) |
missense |
probably benign |
0.33 |
|
IGL03352:Vmn1r64
|
APN |
7 |
5,887,070 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0200:Vmn1r64
|
UTSW |
7 |
5,886,817 (GRCm39) |
missense |
probably benign |
0.38 |
|
R0540:Vmn1r64
|
UTSW |
7 |
5,887,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0655:Vmn1r64
|
UTSW |
7 |
5,887,207 (GRCm39) |
missense |
probably benign |
0.25 |
|
R1212:Vmn1r64
|
UTSW |
7 |
5,887,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1579:Vmn1r64
|
UTSW |
7 |
5,886,803 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2034:Vmn1r64
|
UTSW |
7 |
5,886,988 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2221:Vmn1r64
|
UTSW |
7 |
5,887,448 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2240:Vmn1r64
|
UTSW |
7 |
5,887,369 (GRCm39) |
nonsense |
probably null |
|
|
R2305:Vmn1r64
|
UTSW |
7 |
5,887,535 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3019:Vmn1r64
|
UTSW |
7 |
5,887,226 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4256:Vmn1r64
|
UTSW |
7 |
5,886,895 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4666:Vmn1r64
|
UTSW |
7 |
5,887,357 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4996:Vmn1r64
|
UTSW |
7 |
5,887,052 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5682:Vmn1r64
|
UTSW |
7 |
5,886,622 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5730:Vmn1r64
|
UTSW |
7 |
5,887,522 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7397:Vmn1r64
|
UTSW |
7 |
5,887,013 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R9697:Vmn1r64
|
UTSW |
7 |
5,886,859 (GRCm39) |
missense |
probably benign |
0.04 |
|
X0063:Vmn1r64
|
UTSW |
7 |
5,887,349 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Posted On |
2014-02-04 |
Incidental Mutation