Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01817:Nme1nme2'

154430

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Nme1nme2

Ensembl Gene

ENSMUSG00000091228

Gene Name

NME/NM23 nucleoside diphosphate kinase 1 and 2 readthrough

Synonyms

Gm20390

Accession Numbers

Essential gene?

Not available question?

Stock #

IGL01817

Quality Score

Status

Chromosome

Chromosomal Location

93840645-93859119 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

G to T at 93846447 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000117022 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000021217] [ENSMUST00000021220] [ENSMUST00000072566] [ENSMUST00000135884] [ENSMUST00000170303]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000021217

SMART Domains

Protein: ENSMUSP00000021217
Gene: ENSMUSG00000020857

Domain	Start	End	E-Value	Type
NDK	4	141	2.8e-90	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000021220

SMART Domains

Protein: ENSMUSP00000021220
Gene: ENSMUSG00000037601

Domain	Start	End	E-Value	Type
NDK	4	127	8.86e-70	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000072566

SMART Domains

Protein: ENSMUSP00000103476
Gene: ENSMUSG00000020857

Domain	Start	End	E-Value	Type
NDK	4	141	2.8e-90	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000135884

SMART Domains

Protein: ENSMUSP00000117022
Gene: ENSMUSG00000037601

Domain	Start	End	E-Value	Type
NDK	4	141	5.74e-87	SMART

Predicted Effect

silent
Transcript: ENSMUST00000170303

SMART Domains

Protein: ENSMUSP00000132590
Gene: ENSMUSG00000091228

Domain	Start	End	E-Value	Type
NDK	4	118	7.56e-55	SMART
NDK	119	256	2.8e-90	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 21 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Eif4g3	T	C	4: 137,847,673 (GRCm39)	V198A	probably benign	Het
Exoc6b	T	C	6: 85,046,320 (GRCm39)	E23G	probably damaging	Het
Gm4847	C	A	1: 166,462,471 (GRCm39)	D340Y	probably damaging	Het
Gtf3c5	T	C	2: 28,459,301 (GRCm39)		probably null	Het
Ighv1-13	G	A	12: 114,594,600 (GRCm39)		probably benign	Het
Ighv1-43	C	A	12: 114,909,714 (GRCm39)	E69D	probably benign	Het
Ighv1-43	T	C	12: 114,909,715 (GRCm39)	E69G	probably benign	Het
Itln1	C	A	1: 171,356,728 (GRCm39)	L138F	probably damaging	Het
Nsun5	G	T	5: 135,398,893 (GRCm39)	G19V	probably damaging	Het
Or4a78	A	G	2: 89,497,348 (GRCm39)	I294T	probably benign	Het
Or4c118	A	G	2: 88,974,702 (GRCm39)	F222L	probably benign	Het
Or51ai2	A	G	7: 103,587,030 (GRCm39)	I148V	probably benign	Het
Per1	T	C	11: 68,995,025 (GRCm39)	L615P	probably damaging	Het
Pibf1	C	A	14: 99,423,908 (GRCm39)		probably benign	Het
Pik3r4	T	A	9: 105,528,021 (GRCm39)	I458N	probably damaging	Het
Ppp1r14a	T	C	7: 28,992,622 (GRCm39)	V108A	probably benign	Het
Scamp2	T	A	9: 57,488,903 (GRCm39)	C201*	probably null	Het
Speer1c	C	A	5: 10,295,297 (GRCm39)	A48S	probably damaging	Het
Stambpl1	G	T	19: 34,211,393 (GRCm39)	L151F	possibly damaging	Het
Tent5c	T	C	3: 100,380,171 (GRCm39)	Y195C	probably damaging	Het
Vmn1r64	G	A	7: 5,887,222 (GRCm39)	T107I	probably damaging	Het

Other mutations in Nme1nme2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02475:Nme1nme2	APN	11	93,846,400 (GRCm39)	missense	probably damaging	1.00
IGL02620:Nme1nme2	APN	11	93,843,682 (GRCm39)	missense	possibly damaging	0.69

Posted On

2014-02-04