Incidental Mutation 'IGL01828:Vmn1r88'
ID154700
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r88
Ensembl Gene ENSMUSG00000095902
Gene Namevomeronasal 1 receptor, 88
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.062) question?
Stock #IGL01828
Quality Score
Status
Chromosome7
Chromosomal Location13177719-13178669 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) C to T at 13177735 bp
ZygosityHeterozygous
Amino Acid Change Threonine to Isoleucine at position 6 (T6I)
Ref Sequence ENSEMBL: ENSMUSP00000128946 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000171783]
Predicted Effect noncoding transcript
Transcript: ENSMUST00000122190
Predicted Effect probably damaging
Transcript: ENSMUST00000171783
AA Change: T6I

PolyPhen 2 Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
SMART Domains Protein: ENSMUSP00000128946
Gene: ENSMUSG00000095902
AA Change: T6I

DomainStartEndE-ValueType
Pfam:TAS2R 1 306 2e-14 PFAM
Pfam:V1R 35 301 1.4e-30 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 20 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca5 T C 11: 110,287,695 I1151V probably benign Het
Abcc4 C T 14: 118,553,279 probably benign Het
Asxl3 T A 18: 22,525,558 probably benign Het
Car4 C A 11: 84,964,745 Q198K probably benign Het
Ces1a T C 8: 93,025,201 H435R probably damaging Het
Chdh T A 14: 30,036,608 F503L probably damaging Het
Dennd4a C T 9: 64,842,561 R145* probably null Het
Dse T A 10: 34,152,776 T773S probably damaging Het
Fbxw11 T A 11: 32,720,505 L123H probably damaging Het
Gigyf2 A G 1: 87,419,098 D550G probably damaging Het
Krcc1 T A 6: 71,284,367 Y128N probably damaging Het
Myh8 T C 11: 67,303,826 M1621T possibly damaging Het
Notch2 T A 3: 98,072,613 C148S probably damaging Het
Plcg2 C A 8: 117,590,233 H616Q probably damaging Het
Plec T C 15: 76,183,755 E1218G probably damaging Het
Plekhm2 T C 4: 141,629,585 E749G probably benign Het
RP24-77E13.10 T C 7: 7,231,323 probably null Het
Slco1a6 C T 6: 142,096,411 V480M probably damaging Het
Vmn2r14 A G 5: 109,224,577 F16L possibly damaging Het
Ywhab G A 2: 164,011,774 R57H possibly damaging Het
Other mutations in Vmn1r88
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01879:Vmn1r88 APN 7 13178302 missense probably benign 0.12
IGL02028:Vmn1r88 APN 7 13177792 missense probably benign
IGL02586:Vmn1r88 APN 7 13177808 nonsense probably null
IGL03176:Vmn1r88 APN 7 13177852 missense probably damaging 1.00
PIT4466001:Vmn1r88 UTSW 7 13178476 missense possibly damaging 0.83
R1163:Vmn1r88 UTSW 7 13178133 missense probably benign
R1478:Vmn1r88 UTSW 7 13177951 missense probably damaging 1.00
R2376:Vmn1r88 UTSW 7 13177858 missense probably damaging 0.99
R3624:Vmn1r88 UTSW 7 13177863 missense probably benign 0.08
R4543:Vmn1r88 UTSW 7 13177980 missense possibly damaging 0.52
R4593:Vmn1r88 UTSW 7 13177842 missense probably damaging 0.96
R4721:Vmn1r88 UTSW 7 13178524 nonsense probably null
R5927:Vmn1r88 UTSW 7 13178513 missense probably benign 0.12
R6411:Vmn1r88 UTSW 7 13178043 missense probably damaging 1.00
R6535:Vmn1r88 UTSW 7 13178185 missense probably benign 0.03
R6598:Vmn1r88 UTSW 7 13178223 missense probably damaging 1.00
R6857:Vmn1r88 UTSW 7 13178331 missense possibly damaging 0.87
Posted On2014-02-04