Incidental Mutation 'IGL01833:1700061G19Rik'
ID154839
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol 1700061G19Rik
Ensembl Gene ENSMUSG00000024209
Gene NameRIKEN cDNA 1700061G19 gene
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.069) question?
Stock #IGL01833
Quality Score
Status
Chromosome17
Chromosomal Location56875477-56888904 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 56881062 bp
ZygosityHeterozygous
Amino Acid Change Asparagine to Serine at position 190 (N190S)
Ref Sequence ENSEMBL: ENSMUSP00000025048 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000025048]
Predicted Effect probably benign
Transcript: ENSMUST00000025048
AA Change: N190S

PolyPhen 2 Score 0.016 (Sensitivity: 0.95; Specificity: 0.79)
SMART Domains Protein: ENSMUSP00000025048
Gene: ENSMUSG00000024209
AA Change: N190S

DomainStartEndE-ValueType
low complexity region 16 27 N/A INTRINSIC
Pfam:AMP-binding 80 554 6.5e-68 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000125425
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 36 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adamts18 T A 8: 113,743,096 Y658F probably benign Het
Camsap3 T A 8: 3,608,508 L1151Q probably damaging Het
Casp14 T A 10: 78,715,403 Y16F probably damaging Het
Clip2 A T 5: 134,498,084 probably benign Het
Clip4 G A 17: 71,827,790 probably benign Het
Cyb5r4 G A 9: 87,059,452 probably null Het
Ep400 A T 5: 110,680,008 N2329K unknown Het
Fam163a T A 1: 156,079,996 I17F probably damaging Het
Fam213b G T 4: 154,896,602 probably benign Het
Galnt1 T A 18: 24,267,560 I241N probably damaging Het
Galnt14 T G 17: 73,504,904 I441L probably benign Het
Gpr45 T C 1: 43,032,242 L15P probably benign Het
Hivep1 A T 13: 42,154,988 K235* probably null Het
Kcnip2 T C 19: 45,794,307 probably null Het
Kpna3 T C 14: 61,370,445 N437S possibly damaging Het
Lmtk2 A T 5: 144,175,935 R1158* probably null Het
Lpo A G 11: 87,807,333 V612A possibly damaging Het
Myh15 T C 16: 49,114,058 C663R probably damaging Het
Nacad G A 11: 6,605,700 R17C unknown Het
Olfr1351 A T 10: 79,017,936 M205L probably benign Het
Pcsk2 A G 2: 143,687,580 Q99R possibly damaging Het
Pkd1l2 T C 8: 117,060,525 N593S probably benign Het
Plce1 G A 19: 38,720,981 S1093N probably damaging Het
Rhpn2 T A 7: 35,376,171 Y258N probably benign Het
Serpinb9d T C 13: 33,200,705 Y222H probably damaging Het
Shprh T C 10: 11,191,062 L1401P probably damaging Het
Slc5a7 A G 17: 54,281,833 L262P probably damaging Het
Stat2 T G 10: 128,281,176 F293V probably benign Het
Stpg4 T A 17: 87,395,157 probably null Het
Styk1 G T 6: 131,302,366 probably benign Het
Sult2a2 T A 7: 13,734,796 D62E probably damaging Het
Sytl2 G A 7: 90,396,537 V632M probably damaging Het
Themis C T 10: 28,782,311 Q445* probably null Het
Tmem225 A T 9: 40,148,429 E35V probably damaging Het
Vmn1r48 T A 6: 90,036,283 T187S probably damaging Het
Xpnpep1 A G 19: 53,000,393 Y463H probably damaging Het
Other mutations in 1700061G19Rik
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01287:1700061G19Rik APN 17 56882203 nonsense probably null
IGL02420:1700061G19Rik APN 17 56880494 missense probably damaging 1.00
IGL02969:1700061G19Rik APN 17 56883751 missense probably damaging 1.00
IGL03054:1700061G19Rik UTSW 17 56886528 missense possibly damaging 0.67
R0197:1700061G19Rik UTSW 17 56883835 missense probably benign 0.01
R0257:1700061G19Rik UTSW 17 56885169 nonsense probably null
R0279:1700061G19Rik UTSW 17 56885169 nonsense probably null
R0280:1700061G19Rik UTSW 17 56885169 nonsense probably null
R0281:1700061G19Rik UTSW 17 56885169 nonsense probably null
R0282:1700061G19Rik UTSW 17 56885169 nonsense probably null
R0329:1700061G19Rik UTSW 17 56883631 missense probably benign 0.02
R0330:1700061G19Rik UTSW 17 56883631 missense probably benign 0.02
R0349:1700061G19Rik UTSW 17 56885169 nonsense probably null
R0518:1700061G19Rik UTSW 17 56885169 nonsense probably null
R0519:1700061G19Rik UTSW 17 56885169 nonsense probably null
R0521:1700061G19Rik UTSW 17 56885169 nonsense probably null
R0604:1700061G19Rik UTSW 17 56885169 nonsense probably null
R0883:1700061G19Rik UTSW 17 56883835 missense probably benign 0.01
R1561:1700061G19Rik UTSW 17 56877431 missense probably benign
R1779:1700061G19Rik UTSW 17 56885169 nonsense probably null
R2008:1700061G19Rik UTSW 17 56886478 missense probably benign 0.04
R2102:1700061G19Rik UTSW 17 56884949 nonsense probably null
R2247:1700061G19Rik UTSW 17 56877435 missense possibly damaging 0.83
R2484:1700061G19Rik UTSW 17 56882641 missense probably benign 0.00
R2917:1700061G19Rik UTSW 17 56885141 missense probably damaging 1.00
R3149:1700061G19Rik UTSW 17 56876348 missense probably benign
R3773:1700061G19Rik UTSW 17 56876262 start codon destroyed probably null 0.00
R4829:1700061G19Rik UTSW 17 56883500 splice site probably null
R4860:1700061G19Rik UTSW 17 56888655 missense probably benign 0.09
R4860:1700061G19Rik UTSW 17 56888655 missense probably benign 0.09
R4887:1700061G19Rik UTSW 17 56876324 missense possibly damaging 0.84
R5043:1700061G19Rik UTSW 17 56885198 missense probably damaging 1.00
R5112:1700061G19Rik UTSW 17 56877465 missense probably benign 0.03
R5161:1700061G19Rik UTSW 17 56882888 missense possibly damaging 0.84
R5214:1700061G19Rik UTSW 17 56886493 missense probably benign
R5287:1700061G19Rik UTSW 17 56876221 unclassified probably benign
R5403:1700061G19Rik UTSW 17 56876221 unclassified probably benign
R5779:1700061G19Rik UTSW 17 56881061 missense probably benign 0.02
R5997:1700061G19Rik UTSW 17 56876373 missense probably benign 0.02
R6198:1700061G19Rik UTSW 17 56882679 missense probably damaging 1.00
R6259:1700061G19Rik UTSW 17 56877513 missense probably benign 0.04
R6357:1700061G19Rik UTSW 17 56877591 critical splice donor site probably null
R6754:1700061G19Rik UTSW 17 56883358 missense probably damaging 0.99
R6842:1700061G19Rik UTSW 17 56877432 missense probably benign 0.00
R7042:1700061G19Rik UTSW 17 56885098 missense possibly damaging 0.73
R7181:1700061G19Rik UTSW 17 56881037 missense probably benign 0.03
R7445:1700061G19Rik UTSW 17 56882973 missense possibly damaging 0.64
R7511:1700061G19Rik UTSW 17 56882954 missense probably damaging 0.98
Z1177:1700061G19Rik UTSW 17 56883463 frame shift probably null
Posted On2014-02-04