Incidental Mutation 'IGL01833:Fam163a'
ID154847
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Fam163a
Ensembl Gene ENSMUSG00000015484
Gene Namefamily with sequence similarity 163, member A
SynonymsA230106N23Rik
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL01833
Quality Score
Status
Chromosome1
Chromosomal Location156075966-156205026 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) T to A at 156079996 bp
ZygosityHeterozygous
Amino Acid Change Isoleucine to Phenylalanine at position 17 (I17F)
Ref Sequence ENSEMBL: ENSMUSP00000015628 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000015628]
Predicted Effect probably damaging
Transcript: ENSMUST00000015628
AA Change: I17F

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000015628
Gene: ENSMUSG00000015484
AA Change: I17F

DomainStartEndE-ValueType
Pfam:FAM163 1 168 7.9e-65 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 36 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700061G19Rik A G 17: 56,881,062 N190S probably benign Het
Adamts18 T A 8: 113,743,096 Y658F probably benign Het
Camsap3 T A 8: 3,608,508 L1151Q probably damaging Het
Casp14 T A 10: 78,715,403 Y16F probably damaging Het
Clip2 A T 5: 134,498,084 probably benign Het
Clip4 G A 17: 71,827,790 probably benign Het
Cyb5r4 G A 9: 87,059,452 probably null Het
Ep400 A T 5: 110,680,008 N2329K unknown Het
Fam213b G T 4: 154,896,602 probably benign Het
Galnt1 T A 18: 24,267,560 I241N probably damaging Het
Galnt14 T G 17: 73,504,904 I441L probably benign Het
Gpr45 T C 1: 43,032,242 L15P probably benign Het
Hivep1 A T 13: 42,154,988 K235* probably null Het
Kcnip2 T C 19: 45,794,307 probably null Het
Kpna3 T C 14: 61,370,445 N437S possibly damaging Het
Lmtk2 A T 5: 144,175,935 R1158* probably null Het
Lpo A G 11: 87,807,333 V612A possibly damaging Het
Myh15 T C 16: 49,114,058 C663R probably damaging Het
Nacad G A 11: 6,605,700 R17C unknown Het
Olfr1351 A T 10: 79,017,936 M205L probably benign Het
Pcsk2 A G 2: 143,687,580 Q99R possibly damaging Het
Pkd1l2 T C 8: 117,060,525 N593S probably benign Het
Plce1 G A 19: 38,720,981 S1093N probably damaging Het
Rhpn2 T A 7: 35,376,171 Y258N probably benign Het
Serpinb9d T C 13: 33,200,705 Y222H probably damaging Het
Shprh T C 10: 11,191,062 L1401P probably damaging Het
Slc5a7 A G 17: 54,281,833 L262P probably damaging Het
Stat2 T G 10: 128,281,176 F293V probably benign Het
Stpg4 T A 17: 87,395,157 probably null Het
Styk1 G T 6: 131,302,366 probably benign Het
Sult2a2 T A 7: 13,734,796 D62E probably damaging Het
Sytl2 G A 7: 90,396,537 V632M probably damaging Het
Themis C T 10: 28,782,311 Q445* probably null Het
Tmem225 A T 9: 40,148,429 E35V probably damaging Het
Vmn1r48 T A 6: 90,036,283 T187S probably damaging Het
Xpnpep1 A G 19: 53,000,393 Y463H probably damaging Het
Other mutations in Fam163a
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0318:Fam163a UTSW 1 156079969 missense probably damaging 1.00
R1813:Fam163a UTSW 1 156080041 missense probably damaging 1.00
R6216:Fam163a UTSW 1 156078995 missense probably benign 0.00
R7202:Fam163a UTSW 1 156079088 missense probably damaging 1.00
R7754:Fam163a UTSW 1 156079983 missense probably damaging 1.00
Posted On2014-02-04