Incidental Mutation 'IGL01836:Adh6a'
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ID154968
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Adh6a
Ensembl Gene ENSMUSG00000053054
Gene Namealcohol dehydrogenase 6A (class V)
Synonyms1810009C16Rik, Adh5a
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.113) question?
Stock #IGL01836
Quality Score
Status
Chromosome3
Chromosomal Location138313286-138331134 bp(+) (GRCm38)
Type of Mutationutr 5 prime
DNA Base Change (assembly) A to G at 138313336 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000101854 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000013455] [ENSMUST00000106247]
Predicted Effect probably benign
Transcript: ENSMUST00000013455
SMART Domains Protein: ENSMUSP00000013455
Gene: ENSMUSG00000053054

DomainStartEndE-ValueType
Pfam:ADH_N 34 161 3.9e-27 PFAM
Pfam:ADH_zinc_N 203 334 1.2e-21 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000106247
SMART Domains Protein: ENSMUSP00000101854
Gene: ENSMUSG00000053054

DomainStartEndE-ValueType
Pfam:ADH_N 34 161 6.1e-25 PFAM
Pfam:ADH_zinc_N 203 334 2.4e-20 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 27 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Atp1a1 C T 3: 101,591,414 G188R probably damaging Het
Cadps A G 14: 12,522,311 Y618H probably damaging Het
Dot1l T C 10: 80,785,866 S451P probably benign Het
Dpysl4 G A 7: 139,096,173 V294I possibly damaging Het
Ehmt1 T A 2: 24,863,220 probably null Het
Eps8 C T 6: 137,483,541 probably null Het
Gm7247 T A 14: 51,365,396 I63K probably damaging Het
Gsdme T A 6: 50,222,789 D270V probably damaging Het
Kel T A 6: 41,697,438 T353S possibly damaging Het
Krt73 T C 15: 101,795,896 H403R probably benign Het
Mrnip A G 11: 50,199,848 T280A probably benign Het
Olfr342 C T 2: 36,527,825 Q138* probably null Het
Pkdrej A G 15: 85,820,958 L259P probably damaging Het
Plod2 T C 9: 92,606,498 probably benign Het
Rad54l2 A G 9: 106,716,157 S415P probably benign Het
Rag1 A T 2: 101,641,894 F968I probably damaging Het
Rreb1 T C 13: 37,931,457 S931P probably damaging Het
Sec23a T C 12: 58,971,287 I618V probably damaging Het
Smtnl1 A T 2: 84,815,370 F386I probably damaging Het
Sppl2b C T 10: 80,861,386 T30I probably benign Het
Srf T C 17: 46,549,182 probably benign Het
Tbc1d22b A G 17: 29,599,958 T429A probably damaging Het
Tcf20 A T 15: 82,855,155 D698E probably damaging Het
Tmem106c C A 15: 97,969,686 S250R probably benign Het
Tmprss3 A G 17: 31,191,044 S199P probably benign Het
Ush2a C T 1: 188,759,863 probably benign Het
Zfp595 A G 13: 67,332,461 probably benign Het
Other mutations in Adh6a
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02535:Adh6a APN 3 138327390 missense probably benign
IGL02942:Adh6a APN 3 138324881 missense probably damaging 1.00
IGL03162:Adh6a APN 3 138329119 nonsense probably null
R0785:Adh6a UTSW 3 138329068 splice site probably benign
R1809:Adh6a UTSW 3 138330961 missense possibly damaging 0.68
R2065:Adh6a UTSW 3 138325237 missense probably benign 0.05
R2269:Adh6a UTSW 3 138329096 missense probably benign 0.03
R3834:Adh6a UTSW 3 138327514 critical splice donor site probably null
R3835:Adh6a UTSW 3 138327514 critical splice donor site probably null
R4616:Adh6a UTSW 3 138324947 missense probably damaging 1.00
R4652:Adh6a UTSW 3 138326115 missense probably benign 0.00
R4690:Adh6a UTSW 3 138326171 missense possibly damaging 0.50
R5481:Adh6a UTSW 3 138325958 missense probably damaging 1.00
R8152:Adh6a UTSW 3 138327514 critical splice donor site probably null
R8377:Adh6a UTSW 3 138326123 missense probably damaging 1.00
R8475:Adh6a UTSW 3 138325218 missense probably benign 0.05
Posted On2014-02-04