Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL01788:Ifna9'

155107

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Ifna9

Ensembl Gene

ENSMUSG00000095270

Gene Name

interferon alpha 9

Synonyms

Ifa9

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.059) question?

Stock #

IGL01788

Quality Score

Status

Chromosome

Chromosomal Location

88591813-88592385 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 88591860 bp

Zygosity

Heterozygous

Amino Acid Change

Serine to Proline at position 176 (S176P)

Ref Sequence

ENSEMBL: ENSMUSP00000099871 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000102807]

Predicted Effect

probably damaging
Transcript: ENSMUST00000102807
AA Change: S176P

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000099871
Gene: ENSMUSG00000095270
AA Change: S176P

Domain	Start	End	E-Value	Type
signal peptide	1	23	N/A	INTRINSIC
IFabd	58	175	1.68e-67	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 41 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
9230009I02Rik	T	G	11: 51,091,715		noncoding transcript	Het
Acp6	A	G	3: 97,165,882	T80A	probably damaging	Het
Adamtsl5	T	C	10: 80,344,923	T102A	probably benign	Het
Adcy6	C	A	15: 98,596,519	E812*	probably null	Het
Apol6	G	A	15: 77,051,016	V162I	possibly damaging	Het
Atp6v1h	T	A	1: 5,149,983	M396K	possibly damaging	Het
B3gnt8	A	G	7: 25,629,188	T348A	probably damaging	Het
Cgnl1	A	G	9: 71,655,390	V869A	probably benign	Het
Dcaf5	A	T	12: 80,348,324	I357N	probably damaging	Het
Dennd4a	A	G	9: 64,842,621	I165V	probably benign	Het
Dlgap2	T	A	8: 14,843,631	I982K	probably benign	Het
Dopey1	A	T	9: 86,531,719	H1891L	probably benign	Het
Fhad1	A	C	4: 141,932,802	S65R	probably benign	Het
Fn1	A	G	1: 71,613,837	I1331T	probably damaging	Het
Fto	A	T	8: 91,409,731	Y211F	probably benign	Het
Gm3278	A	C	14: 4,893,332	R60S	probably benign	Het
Klk1	T	C	7: 44,228,983	I189T	probably benign	Het
Mcph1	G	A	8: 18,632,403	G519R	probably damaging	Het
Mcph1	G	A	8: 18,632,404	G519E	probably damaging	Het
N4bp1	A	T	8: 86,860,996	V438E	probably benign	Het
Ncapg	T	A	5: 45,671,081	V58E	probably damaging	Het
Nid2	T	A	14: 19,807,979	S1054T	probably damaging	Het
Nlrp4a	A	T	7: 26,454,067	Y681F	probably benign	Het
Olfr1308	T	C	2: 111,961,007	D22G	probably benign	Het
Olfr1442	G	A	19: 12,675,078	R291K	probably damaging	Het
Olfr603	C	A	7: 103,383,563	M146I	probably benign	Het
Olfr726	A	G	14: 50,084,502	Y60H	probably damaging	Het
Papln	A	T	12: 83,775,462	T364S	probably benign	Het
Pcdh18	C	A	3: 49,755,922	E315*	probably null	Het
Pmel	G	A	10: 128,717,832	R445Q	probably damaging	Het
Ppp1r12b	C	T	1: 134,893,507	V182I	possibly damaging	Het
Ptprn2	A	G	12: 116,900,987	T541A	probably damaging	Het
Rbl1	A	T	2: 157,163,656	N813K	probably benign	Het
Sash1	C	A	10: 8,733,646	R713L	probably benign	Het
Slc13a1	T	G	6: 24,134,372	T171P	probably damaging	Het
Slc18b1	G	T	10: 23,826,001	E407D	probably damaging	Het
Slc2a6	G	A	2: 27,024,215	Q297*	probably null	Het
Vmn1r209	T	C	13: 22,805,662	H286R	probably damaging	Het
Vmn1r28	C	A	6: 58,265,537	H122N	probably benign	Het
Wfs1	A	G	5: 36,968,636	Y304H	probably benign	Het
Zfp512b	A	G	2: 181,588,763	S445P	possibly damaging	Het

Other mutations in Ifna9

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02268:Ifna9	APN	4	88592354	nonsense	probably null
R0579:Ifna9	UTSW	4	88592271	missense	possibly damaging	0.84
R1530:Ifna9	UTSW	4	88592172	missense	possibly damaging	0.83
R1663:Ifna9	UTSW	4	88591983	missense	probably benign	0.00
R1872:Ifna9	UTSW	4	88592255	missense	probably damaging	0.97
R3923:Ifna9	UTSW	4	88592271	missense	possibly damaging	0.84
R4534:Ifna9	UTSW	4	88592048	missense	possibly damaging	0.76
R4882:Ifna9	UTSW	4	88592303	missense	probably benign	0.01
R5440:Ifna9	UTSW	4	88591811	splice site	probably null
R6008:Ifna9	UTSW	4	88592363	missense	probably null	1.00
R6464:Ifna9	UTSW	4	88592250	missense	possibly damaging	0.93
R6584:Ifna9	UTSW	4	88592138	missense	probably damaging	0.99
R6899:Ifna9	UTSW	4	88592063	missense	probably damaging	1.00

Posted On

2014-02-04