Incidental Mutation 'IGL01788:Ifna9'
ID155107
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Ifna9
Ensembl Gene ENSMUSG00000095270
Gene Nameinterferon alpha 9
SynonymsIfa9
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.059) question?
Stock #IGL01788
Quality Score
Status
Chromosome4
Chromosomal Location88591813-88592385 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 88591860 bp
ZygosityHeterozygous
Amino Acid Change Serine to Proline at position 176 (S176P)
Ref Sequence ENSEMBL: ENSMUSP00000099871 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000102807]
Predicted Effect probably damaging
Transcript: ENSMUST00000102807
AA Change: S176P

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000099871
Gene: ENSMUSG00000095270
AA Change: S176P

DomainStartEndE-ValueType
signal peptide 1 23 N/A INTRINSIC
IFabd 58 175 1.68e-67 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 41 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
9230009I02Rik T G 11: 51,091,715 noncoding transcript Het
Acp6 A G 3: 97,165,882 T80A probably damaging Het
Adamtsl5 T C 10: 80,344,923 T102A probably benign Het
Adcy6 C A 15: 98,596,519 E812* probably null Het
Apol6 G A 15: 77,051,016 V162I possibly damaging Het
Atp6v1h T A 1: 5,149,983 M396K possibly damaging Het
B3gnt8 A G 7: 25,629,188 T348A probably damaging Het
Cgnl1 A G 9: 71,655,390 V869A probably benign Het
Dcaf5 A T 12: 80,348,324 I357N probably damaging Het
Dennd4a A G 9: 64,842,621 I165V probably benign Het
Dlgap2 T A 8: 14,843,631 I982K probably benign Het
Dopey1 A T 9: 86,531,719 H1891L probably benign Het
Fhad1 A C 4: 141,932,802 S65R probably benign Het
Fn1 A G 1: 71,613,837 I1331T probably damaging Het
Fto A T 8: 91,409,731 Y211F probably benign Het
Gm3278 A C 14: 4,893,332 R60S probably benign Het
Klk1 T C 7: 44,228,983 I189T probably benign Het
Mcph1 G A 8: 18,632,403 G519R probably damaging Het
Mcph1 G A 8: 18,632,404 G519E probably damaging Het
N4bp1 A T 8: 86,860,996 V438E probably benign Het
Ncapg T A 5: 45,671,081 V58E probably damaging Het
Nid2 T A 14: 19,807,979 S1054T probably damaging Het
Nlrp4a A T 7: 26,454,067 Y681F probably benign Het
Olfr1308 T C 2: 111,961,007 D22G probably benign Het
Olfr1442 G A 19: 12,675,078 R291K probably damaging Het
Olfr603 C A 7: 103,383,563 M146I probably benign Het
Olfr726 A G 14: 50,084,502 Y60H probably damaging Het
Papln A T 12: 83,775,462 T364S probably benign Het
Pcdh18 C A 3: 49,755,922 E315* probably null Het
Pmel G A 10: 128,717,832 R445Q probably damaging Het
Ppp1r12b C T 1: 134,893,507 V182I possibly damaging Het
Ptprn2 A G 12: 116,900,987 T541A probably damaging Het
Rbl1 A T 2: 157,163,656 N813K probably benign Het
Sash1 C A 10: 8,733,646 R713L probably benign Het
Slc13a1 T G 6: 24,134,372 T171P probably damaging Het
Slc18b1 G T 10: 23,826,001 E407D probably damaging Het
Slc2a6 G A 2: 27,024,215 Q297* probably null Het
Vmn1r209 T C 13: 22,805,662 H286R probably damaging Het
Vmn1r28 C A 6: 58,265,537 H122N probably benign Het
Wfs1 A G 5: 36,968,636 Y304H probably benign Het
Zfp512b A G 2: 181,588,763 S445P possibly damaging Het
Other mutations in Ifna9
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02268:Ifna9 APN 4 88592354 nonsense probably null
R0579:Ifna9 UTSW 4 88592271 missense possibly damaging 0.84
R1530:Ifna9 UTSW 4 88592172 missense possibly damaging 0.83
R1663:Ifna9 UTSW 4 88591983 missense probably benign 0.00
R1872:Ifna9 UTSW 4 88592255 missense probably damaging 0.97
R3923:Ifna9 UTSW 4 88592271 missense possibly damaging 0.84
R4534:Ifna9 UTSW 4 88592048 missense possibly damaging 0.76
R4882:Ifna9 UTSW 4 88592303 missense probably benign 0.01
R5440:Ifna9 UTSW 4 88591811 splice site probably null
R6008:Ifna9 UTSW 4 88592363 missense probably null 1.00
R6464:Ifna9 UTSW 4 88592250 missense possibly damaging 0.93
R6584:Ifna9 UTSW 4 88592138 missense probably damaging 0.99
R6899:Ifna9 UTSW 4 88592063 missense probably damaging 1.00
Posted On2014-02-04