Mutagenetix > Incidental Mutation

Incidental Mutation 'R1340:Naip2'

157017

Institutional Source

Beutler Lab

Gene Symbol

Naip2

Ensembl Gene

ENSMUSG00000078945

Gene Name

NLR family, apoptosis inhibitory protein 2

Synonyms

Birc1b, Naip2, Naip-rs6

MMRRC Submission

039405-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.066) question?

Stock #

R1340 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

100144063-100202092 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 100189122 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Leucine to Phenylalanine at position 93 (L93F)

Ref Sequence

ENSEMBL: ENSMUSP00000113890 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000067975] [ENSMUST00000117913] [ENSMUST00000167986]

AlphaFold

Q9QUK4

Predicted Effect

possibly damaging
Transcript: ENSMUST00000067975
AA Change: L93F

PolyPhen 2 Score 0.797 (Sensitivity: 0.84; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000070827
Gene: ENSMUSG00000078945
AA Change: L93F

Domain	Start	End	E-Value	Type
BIR	58	129	7.95e-18	SMART
BIR	157	229	5.31e-37	SMART
BIR	276	347	4.22e-31	SMART
Pfam:NACHT	508	662	1.9e-36	PFAM
low complexity region	954	964	N/A	INTRINSIC
low complexity region	1116	1126	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000117913
AA Change: L93F

PolyPhen 2 Score 0.797 (Sensitivity: 0.84; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000113890
Gene: ENSMUSG00000078945
AA Change: L93F

Domain	Start	End	E-Value	Type
BIR	58	129	7.95e-18	SMART
BIR	157	229	5.31e-37	SMART
BIR	276	347	4.22e-31	SMART
Pfam:NACHT	508	662	1.9e-36	PFAM
low complexity region	954	964	N/A	INTRINSIC
low complexity region	1116	1126	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000167986
AA Change: L93F

PolyPhen 2 Score 0.066 (Sensitivity: 0.94; Specificity: 0.84)

SMART Domains

Protein: ENSMUSP00000125852
Gene: ENSMUSG00000078945
AA Change: L93F

Domain	Start	End	E-Value	Type
BIR	58	129	7.95e-18	SMART
BIR	157	229	5.31e-37	SMART
BIR	276	347	4.22e-31	SMART
Pfam:NACHT	508	662	8.6e-35	PFAM
low complexity region	954	964	N/A	INTRINSIC
low complexity region	1116	1126	N/A	INTRINSIC

Meta Mutation Damage Score

0.1795

Coding Region Coverage

1x: 98.9%
3x: 98.0%
10x: 95.4%
20x: 89.9%

Validation Efficiency

100% (52/52)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Nov 2016]

Allele List at MGI

Other mutations in this stock

Total: 50 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcc9	A	T	6: 142,682,855 (GRCm38)		probably benign	Het
Acat3	C	T	17: 12,929,677 (GRCm38)		probably benign	Het
Actn1	T	C	12: 80,173,144 (GRCm38)		probably null	Het
Adam8	G	A	7: 139,991,377 (GRCm38)	S38F	probably damaging	Het
Aldh9a1	T	G	1: 167,357,344 (GRCm38)	I275S	probably benign	Het
Alkbh2	C	T	5: 114,124,226 (GRCm38)	E148K	probably damaging	Het
Alms1	G	A	6: 85,667,957 (GRCm38)		probably null	Het
Cacna1d	A	G	14: 30,072,067 (GRCm38)	V1539A	probably damaging	Het
Cacna1e	A	G	1: 154,472,657 (GRCm38)	L724P	probably damaging	Het
Ccdc110	A	G	8: 45,942,181 (GRCm38)	T370A	probably benign	Het
Ccdc9	G	A	7: 16,275,390 (GRCm38)		probably benign	Het
Cep120	A	T	18: 53,724,391 (GRCm38)	V334E	probably damaging	Het
Ces3a	C	T	8: 105,057,913 (GRCm38)	P462L	probably damaging	Het
Cgref1	A	G	5: 30,945,346 (GRCm38)		probably benign	Het
Cndp1	G	A	18: 84,634,652 (GRCm38)		probably benign	Het
Csrnp3	T	A	2: 66,002,396 (GRCm38)	F81Y	probably damaging	Het
Ddr2	T	C	1: 169,998,084 (GRCm38)	T316A	probably benign	Het
Dync1h1	G	A	12: 110,636,509 (GRCm38)	E2195K	probably benign	Het
Epb41l5	A	T	1: 119,549,131 (GRCm38)	*740R	probably null	Het
Gfpt2	A	G	11: 49,832,861 (GRCm38)	K559E	probably damaging	Het
Gm2381	A	G	7: 42,820,404 (GRCm38)	Y99H	possibly damaging	Het
Gsdma2	T	C	11: 98,657,649 (GRCm38)	V242A	probably damaging	Het
Lrp1b	T	C	2: 40,702,794 (GRCm38)	N3771S	probably benign	Het
Lrriq4	A	C	3: 30,650,323 (GRCm38)	T167P	possibly damaging	Het
Marc2	T	C	1: 184,822,547 (GRCm38)	T254A	probably benign	Het
Nefh	G	GNNNNNNNNNNNNNNNNNN	11: 4,941,002 (GRCm38)		probably benign	Het
Nrp1	T	C	8: 128,434,355 (GRCm38)	S321P	probably damaging	Het
Nt5c1b	T	C	12: 10,377,276 (GRCm38)	V342A	probably damaging	Het
Nt5c3	A	G	6: 56,883,033 (GRCm38)	M273T	probably benign	Het
Olfr364-ps1	T	G	2: 37,146,757 (GRCm38)	L182V	probably benign	Het
Olfr449	G	A	6: 42,838,009 (GRCm38)	V43M	probably benign	Het
Olfr527	A	G	7: 140,336,125 (GRCm38)	T88A	probably benign	Het
Polr3f	A	G	2: 144,538,628 (GRCm38)	H297R	probably benign	Het
Ptgs2	T	G	1: 150,105,477 (GRCm38)	F504V	probably damaging	Het
Ptpro	C	T	6: 137,441,081 (GRCm38)	P142L	possibly damaging	Het
Rps17	A	G	7: 81,343,733 (GRCm38)		probably null	Het
Ryr1	A	G	7: 29,116,012 (GRCm38)	S132P	probably damaging	Het
Sacs	T	C	14: 61,204,509 (GRCm38)	S1335P	probably damaging	Het
Senp6	T	C	9: 80,122,023 (GRCm38)	V383A	possibly damaging	Het
Skint7	T	C	4: 111,980,219 (GRCm38)	F65L	probably damaging	Het
Slc35f1	T	C	10: 53,089,454 (GRCm38)	Y322H	probably damaging	Het
Slc38a4	C	A	15: 97,010,272 (GRCm38)		probably benign	Het
Sned1	G	A	1: 93,281,654 (GRCm38)	V830M	possibly damaging	Het
Sox15	T	A	11: 69,655,547 (GRCm38)	S59T	probably damaging	Het
Srcap	T	A	7: 127,560,738 (GRCm38)		probably benign	Het
Txlnb	A	T	10: 17,842,740 (GRCm38)	I440F	probably damaging	Het
Uhrf1bp1	A	G	17: 27,894,721 (GRCm38)	N1289S	probably benign	Het
Vmn1r178	A	G	7: 23,893,856 (GRCm38)	S37G	probably benign	Het
Vmn2r75	T	C	7: 86,148,590 (GRCm38)	T672A	probably damaging	Het
Wscd1	T	C	11: 71,768,760 (GRCm38)	V222A	probably benign	Het

Other mutations in Naip2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00515:Naip2	APN	13	100,154,887 (GRCm38)	missense	probably benign	0.00
IGL00676:Naip2	APN	13	100,152,632 (GRCm38)	missense	probably damaging	1.00
IGL00870:Naip2	APN	13	100,152,060 (GRCm38)	splice site	probably benign
IGL00908:Naip2	APN	13	100,160,649 (GRCm38)	missense	probably benign	0.01
IGL00916:Naip2	APN	13	100,161,431 (GRCm38)	missense	probably damaging	0.97
IGL00949:Naip2	APN	13	100,161,591 (GRCm38)	missense	probably damaging	1.00
IGL01010:Naip2	APN	13	100,154,938 (GRCm38)	missense	probably damaging	0.99
IGL01642:Naip2	APN	13	100,160,937 (GRCm38)	missense	probably damaging	0.97
IGL01884:Naip2	APN	13	100,188,821 (GRCm38)	splice site	probably benign
IGL01917:Naip2	APN	13	100,162,083 (GRCm38)	missense	probably benign	0.00
IGL02015:Naip2	APN	13	100,161,607 (GRCm38)	missense	possibly damaging	0.57
IGL02315:Naip2	APN	13	100,161,236 (GRCm38)	missense	probably damaging	1.00
IGL02328:Naip2	APN	13	100,161,369 (GRCm38)	missense	probably damaging	1.00
IGL02735:Naip2	APN	13	100,160,214 (GRCm38)	missense	probably damaging	0.99
IGL02738:Naip2	APN	13	100,189,177 (GRCm38)	missense	probably benign	0.01
IGL02887:Naip2	APN	13	100,161,512 (GRCm38)	missense	possibly damaging	0.90
IGL02894:Naip2	APN	13	100,183,789 (GRCm38)	missense	probably benign
IGL02894:Naip2	APN	13	100,160,997 (GRCm38)	missense	probably damaging	1.00
IGL02974:Naip2	APN	13	100,161,678 (GRCm38)	missense	probably damaging	1.00
IGL03024:Naip2	APN	13	100,189,354 (GRCm38)	missense	possibly damaging	0.50
IGL03056:Naip2	APN	13	100,162,287 (GRCm38)	missense	possibly damaging	0.90
IGL03281:Naip2	APN	13	100,161,620 (GRCm38)	missense	probably damaging	0.99
R0131:Naip2	UTSW	13	100,183,788 (GRCm38)	missense	probably benign	0.01
R0131:Naip2	UTSW	13	100,183,788 (GRCm38)	missense	probably benign	0.01
R0132:Naip2	UTSW	13	100,183,788 (GRCm38)	missense	probably benign	0.01
R0310:Naip2	UTSW	13	100,148,842 (GRCm38)	missense	probably damaging	1.00
R0367:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R0368:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R0422:Naip2	UTSW	13	100,161,113 (GRCm38)	missense	probably benign	0.10
R0441:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R0445:Naip2	UTSW	13	100,161,887 (GRCm38)	missense	possibly damaging	0.91
R0446:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R0464:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R0466:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R0467:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R0486:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R0533:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R0853:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R0853:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R0855:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R0855:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R0904:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R0904:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R0906:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R0906:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R0908:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R0908:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R0959:Naip2	UTSW	13	100,154,911 (GRCm38)	missense	probably benign	0.03
R0959:Naip2	UTSW	13	100,154,878 (GRCm38)	missense	probably benign	0.01
R0962:Naip2	UTSW	13	100,179,385 (GRCm38)	missense	probably damaging	1.00
R1024:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R1024:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R1186:Naip2	UTSW	13	100,162,037 (GRCm38)	frame shift	probably null
R1186:Naip2	UTSW	13	100,161,981 (GRCm38)	missense	possibly damaging	0.63
R1217:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R1217:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R1342:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R1342:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R1404:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R1423:Naip2	UTSW	13	100,154,847 (GRCm38)	intron	probably benign
R1423:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R1423:Naip2	UTSW	13	100,154,878 (GRCm38)	missense	probably benign	0.01
R1423:Naip2	UTSW	13	100,154,872 (GRCm38)	missense	possibly damaging	0.59
R1426:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R1426:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R1472:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R1575:Naip2	UTSW	13	100,155,029 (GRCm38)	intron	probably benign
R1575:Naip2	UTSW	13	100,155,021 (GRCm38)	missense	probably benign	0.00
R1576:Naip2	UTSW	13	100,155,021 (GRCm38)	missense	probably benign	0.00
R1576:Naip2	UTSW	13	100,155,029 (GRCm38)	intron	probably benign
R1599:Naip2	UTSW	13	100,161,981 (GRCm38)	missense	possibly damaging	0.63
R1640:Naip2	UTSW	13	100,161,981 (GRCm38)	missense	possibly damaging	0.63
R1641:Naip2	UTSW	13	100,161,981 (GRCm38)	missense	possibly damaging	0.63
R1642:Naip2	UTSW	13	100,161,981 (GRCm38)	missense	possibly damaging	0.63
R1643:Naip2	UTSW	13	100,161,981 (GRCm38)	missense	possibly damaging	0.63
R1644:Naip2	UTSW	13	100,182,929 (GRCm38)	missense	possibly damaging	0.83
R1681:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R1681:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R1891:Naip2	UTSW	13	100,154,887 (GRCm38)	missense	probably benign	0.00
R1913:Naip2	UTSW	13	100,152,157 (GRCm38)	critical splice acceptor site	probably null
R1937:Naip2	UTSW	13	100,161,860 (GRCm38)	missense	probably benign	0.00
R1937:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign
R1993:Naip2	UTSW	13	100,162,007 (GRCm38)	missense	probably benign	0.03
R2001:Naip2	UTSW	13	100,144,588 (GRCm38)	missense	probably damaging	1.00
R2055:Naip2	UTSW	13	100,179,372 (GRCm38)	missense	probably benign	0.07
R2198:Naip2	UTSW	13	100,152,592 (GRCm38)	missense	probably damaging	1.00
R2906:Naip2	UTSW	13	100,161,996 (GRCm38)	missense	probably damaging	1.00
R2931:Naip2	UTSW	13	100,155,021 (GRCm38)	missense	probably benign	0.00
R3014:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R3016:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R3037:Naip2	UTSW	13	100,154,949 (GRCm38)	missense	probably benign	0.08
R3414:Naip2	UTSW	13	100,189,263 (GRCm38)	nonsense	probably null
R3437:Naip2	UTSW	13	100,154,911 (GRCm38)	missense	probably benign	0.03
R3713:Naip2	UTSW	13	100,161,902 (GRCm38)	missense	probably damaging	1.00
R3806:Naip2	UTSW	13	100,152,634 (GRCm38)	missense	possibly damaging	0.92
R3847:Naip2	UTSW	13	100,179,432 (GRCm38)	missense	probably damaging	1.00
R3847:Naip2	UTSW	13	100,179,433 (GRCm38)	missense	probably damaging	1.00
R3848:Naip2	UTSW	13	100,179,432 (GRCm38)	missense	probably damaging	1.00
R3848:Naip2	UTSW	13	100,179,433 (GRCm38)	missense	probably damaging	1.00
R3849:Naip2	UTSW	13	100,179,432 (GRCm38)	missense	probably damaging	1.00
R3849:Naip2	UTSW	13	100,179,433 (GRCm38)	missense	probably damaging	1.00
R3850:Naip2	UTSW	13	100,179,432 (GRCm38)	missense	probably damaging	1.00
R3850:Naip2	UTSW	13	100,179,433 (GRCm38)	missense	probably damaging	1.00
R3891:Naip2	UTSW	13	100,161,098 (GRCm38)	missense	probably damaging	0.99
R4419:Naip2	UTSW	13	100,160,625 (GRCm38)	missense	probably benign	0.03
R4456:Naip2	UTSW	13	100,154,911 (GRCm38)	missense	probably benign	0.03
R4458:Naip2	UTSW	13	100,154,911 (GRCm38)	missense	probably benign	0.03
R4689:Naip2	UTSW	13	100,148,812 (GRCm38)	missense	probably damaging	1.00
R4797:Naip2	UTSW	13	100,161,735 (GRCm38)	missense	probably damaging	1.00
R4852:Naip2	UTSW	13	100,161,536 (GRCm38)	missense	probably benign
R4922:Naip2	UTSW	13	100,154,960 (GRCm38)	missense	probably benign
R5135:Naip2	UTSW	13	100,179,440 (GRCm38)	missense	probably damaging	0.98
R5185:Naip2	UTSW	13	100,189,351 (GRCm38)	missense	probably damaging	1.00
R5265:Naip2	UTSW	13	100,152,560 (GRCm38)	missense	probably damaging	1.00
R5451:Naip2	UTSW	13	100,188,860 (GRCm38)	missense	probably benign	0.12
R5521:Naip2	UTSW	13	100,154,914 (GRCm38)	missense	probably damaging	1.00
R5737:Naip2	UTSW	13	100,161,854 (GRCm38)	missense	probably benign	0.38
R6244:Naip2	UTSW	13	100,152,137 (GRCm38)	missense	probably damaging	1.00
R6478:Naip2	UTSW	13	100,162,041 (GRCm38)	missense	probably benign
R6480:Naip2	UTSW	13	100,162,041 (GRCm38)	missense	probably benign
R6481:Naip2	UTSW	13	100,162,041 (GRCm38)	missense	probably benign
R6490:Naip2	UTSW	13	100,160,685 (GRCm38)	missense	probably benign
R6653:Naip2	UTSW	13	100,152,136 (GRCm38)	missense	probably benign	0.00
R6653:Naip2	UTSW	13	100,161,844 (GRCm38)	missense	probably benign
R6768:Naip2	UTSW	13	100,178,324 (GRCm38)	nonsense	probably null
R6791:Naip2	UTSW	13	100,154,960 (GRCm38)	missense	probably benign
R6793:Naip2	UTSW	13	100,154,960 (GRCm38)	missense	probably benign
R6890:Naip2	UTSW	13	100,162,041 (GRCm38)	missense	probably benign
R7036:Naip2	UTSW	13	100,155,021 (GRCm38)	missense	probably benign	0.00
R7213:Naip2	UTSW	13	100,187,483 (GRCm38)	missense	probably damaging	1.00
R7342:Naip2	UTSW	13	100,189,356 (GRCm38)	missense	probably benign	0.09
R7445:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R7572:Naip2	UTSW	13	100,154,960 (GRCm38)	missense	probably benign
R7699:Naip2	UTSW	13	100,160,369 (GRCm38)	missense	probably benign	0.00
R7840:Naip2	UTSW	13	100,144,409 (GRCm38)	missense	probably benign	0.14
R7874:Naip2	UTSW	13	100,154,960 (GRCm38)	missense	probably benign
R7874:Naip2	UTSW	13	100,154,951 (GRCm38)	missense	probably benign	0.00
R8038:Naip2	UTSW	13	100,162,062 (GRCm38)	missense	probably benign	0.00
R8065:Naip2	UTSW	13	100,189,222 (GRCm38)	missense	probably damaging	1.00
R8094:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R8166:Naip2	UTSW	13	100,162,007 (GRCm38)	missense	probably benign	0.03
R8378:Naip2	UTSW	13	100,161,782 (GRCm38)	missense	probably benign	0.01
R8669:Naip2	UTSW	13	100,188,969 (GRCm38)	missense	probably benign	0.05
R8691:Naip2	UTSW	13	100,161,168 (GRCm38)	missense	probably damaging	1.00
R8716:Naip2	UTSW	13	100,144,406 (GRCm38)	missense	probably benign
R8720:Naip2	UTSW	13	100,162,122 (GRCm38)	missense	probably benign	0.04
R8888:Naip2	UTSW	13	100,189,136 (GRCm38)	missense	probably benign	0.01
R8895:Naip2	UTSW	13	100,189,136 (GRCm38)	missense	probably benign	0.01
R9031:Naip2	UTSW	13	100,178,268 (GRCm38)	missense	possibly damaging	0.55
R9072:Naip2	UTSW	13	100,154,960 (GRCm38)	missense	probably benign
R9072:Naip2	UTSW	13	100,154,951 (GRCm38)	missense	probably benign	0.00
R9074:Naip2	UTSW	13	100,154,960 (GRCm38)	missense	probably benign
R9074:Naip2	UTSW	13	100,154,951 (GRCm38)	missense	probably benign	0.00
R9077:Naip2	UTSW	13	100,154,960 (GRCm38)	missense	probably benign
R9077:Naip2	UTSW	13	100,154,951 (GRCm38)	missense	probably benign	0.00
R9176:Naip2	UTSW	13	100,162,199 (GRCm38)	missense	probably damaging	1.00
R9219:Naip2	UTSW	13	100,160,705 (GRCm38)	missense	probably benign	0.06
R9358:Naip2	UTSW	13	100,161,572 (GRCm38)	missense	probably damaging	1.00
R9371:Naip2	UTSW	13	100,161,846 (GRCm38)	nonsense	probably null
R9414:Naip2	UTSW	13	100,161,735 (GRCm38)	missense	probably damaging	1.00
R9415:Naip2	UTSW	13	100,161,735 (GRCm38)	missense	probably damaging	1.00
R9416:Naip2	UTSW	13	100,161,735 (GRCm38)	missense	probably damaging	1.00
R9708:Naip2	UTSW	13	100,161,579 (GRCm38)	missense	probably damaging	0.99
V5622:Naip2	UTSW	13	100,155,029 (GRCm38)	intron	probably benign
V5622:Naip2	UTSW	13	100,155,021 (GRCm38)	missense	probably benign	0.00
V5622:Naip2	UTSW	13	100,155,021 (GRCm38)	missense	probably benign	0.00
X0063:Naip2	UTSW	13	100,161,758 (GRCm38)	missense	probably damaging	1.00
Y5405:Naip2	UTSW	13	100,154,960 (GRCm38)	missense	probably benign
Z1088:Naip2	UTSW	13	100,161,909 (GRCm38)	missense	probably benign
Z1176:Naip2	UTSW	13	100,161,909 (GRCm38)	missense	probably benign
Z1176:Naip2	UTSW	13	100,161,593 (GRCm38)	missense	probably benign	0.02
Z1177:Naip2	UTSW	13	100,161,909 (GRCm38)	missense	probably benign
Z1177:Naip2	UTSW	13	100,152,629 (GRCm38)	missense	possibly damaging	0.65
Z1177:Naip2	UTSW	13	100,162,865 (GRCm38)	missense	probably benign	0.01

Predicted Primers

PCR Primer
(F):5'- AAAGGACTCCAGTCTTGCCTCCTC -3'
(R):5'- TTTGATGACGACTTGGTCTCTGAGC -3'

Sequencing Primer
(F):5'- GCTTTGTCACCTCTCAGCATC -3'
(R):5'- CTCAGAGTGGATGCACTTTCAG -3'

Posted On

2014-02-11