Incidental Mutation 'R1301:Camta2'
| ID |
158378 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Camta2
|
| Ensembl Gene |
ENSMUSG00000040712 |
| Gene Name |
calmodulin binding transcription activator 2 |
| Synonyms |
Kiaa0909-hp |
| MMRRC Submission |
039367-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.496)
|
| Stock # |
R1301 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
70560289-70578931 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 70567230 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Threonine
at position 675
(I675T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000098493
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000036299]
[ENSMUST00000100933]
[ENSMUST00000108544]
[ENSMUST00000108545]
[ENSMUST00000119120]
[ENSMUST00000120261]
[ENSMUST00000145823]
|
| AlphaFold |
Q80Y50 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000036299
AA Change: I678T
PolyPhen 2
Score 0.034 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000043792
Gene: ENSMUSG00000040712
AA Change: I678T
| Domain | Start | End | E-Value | Type |
|---|
|
CG-1
|
34 |
155 |
1.07e-83 |
SMART |
|
low complexity region
|
232 |
243 |
N/A |
INTRINSIC |
|
low complexity region
|
273 |
291 |
N/A |
INTRINSIC |
|
low complexity region
|
294 |
305 |
N/A |
INTRINSIC |
|
low complexity region
|
314 |
329 |
N/A |
INTRINSIC |
|
low complexity region
|
370 |
380 |
N/A |
INTRINSIC |
|
low complexity region
|
417 |
435 |
N/A |
INTRINSIC |
|
low complexity region
|
461 |
485 |
N/A |
INTRINSIC |
|
low complexity region
|
501 |
514 |
N/A |
INTRINSIC |
|
Pfam:TIG
|
541 |
621 |
6.2e-13 |
PFAM |
|
low complexity region
|
660 |
679 |
N/A |
INTRINSIC |
|
Blast:ANK
|
717 |
750 |
7e-12 |
BLAST |
|
SCOP:d1myo__
|
718 |
816 |
2e-15 |
SMART |
|
Blast:ANK
|
762 |
792 |
4e-11 |
BLAST |
|
low complexity region
|
829 |
839 |
N/A |
INTRINSIC |
|
low complexity region
|
844 |
853 |
N/A |
INTRINSIC |
|
low complexity region
|
861 |
882 |
N/A |
INTRINSIC |
|
IQ
|
1053 |
1075 |
2.59e2 |
SMART |
|
IQ
|
1076 |
1092 |
2.38e2 |
SMART |
|
IQ
|
1106 |
1128 |
5.42e0 |
SMART |
|
low complexity region
|
1140 |
1157 |
N/A |
INTRINSIC |
|
low complexity region
|
1180 |
1190 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000100933
AA Change: I675T
PolyPhen 2
Score 0.178 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000098493
Gene: ENSMUSG00000040712
AA Change: I675T
| Domain | Start | End | E-Value | Type |
|---|
|
CG-1
|
36 |
152 |
8.08e-88 |
SMART |
|
low complexity region
|
229 |
240 |
N/A |
INTRINSIC |
|
low complexity region
|
270 |
288 |
N/A |
INTRINSIC |
|
low complexity region
|
291 |
302 |
N/A |
INTRINSIC |
|
low complexity region
|
311 |
326 |
N/A |
INTRINSIC |
|
low complexity region
|
367 |
377 |
N/A |
INTRINSIC |
|
low complexity region
|
414 |
432 |
N/A |
INTRINSIC |
|
low complexity region
|
458 |
482 |
N/A |
INTRINSIC |
|
low complexity region
|
498 |
511 |
N/A |
INTRINSIC |
|
Pfam:TIG
|
538 |
618 |
1.2e-8 |
PFAM |
|
low complexity region
|
657 |
676 |
N/A |
INTRINSIC |
|
Blast:ANK
|
714 |
747 |
8e-12 |
BLAST |
|
SCOP:d1myo__
|
715 |
813 |
2e-15 |
SMART |
|
Blast:ANK
|
759 |
789 |
4e-11 |
BLAST |
|
low complexity region
|
826 |
836 |
N/A |
INTRINSIC |
|
low complexity region
|
841 |
850 |
N/A |
INTRINSIC |
|
low complexity region
|
858 |
879 |
N/A |
INTRINSIC |
|
IQ
|
1050 |
1072 |
2.59e2 |
SMART |
|
IQ
|
1073 |
1095 |
1.18e1 |
SMART |
|
IQ
|
1096 |
1118 |
5.42e0 |
SMART |
|
low complexity region
|
1130 |
1147 |
N/A |
INTRINSIC |
|
low complexity region
|
1170 |
1180 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108544
AA Change: I673T
PolyPhen 2
Score 0.011 (Sensitivity: 0.96; Specificity: 0.78)
|
| SMART Domains |
Protein: ENSMUSP00000104184
Gene: ENSMUSG00000040712
AA Change: I673T
| Domain | Start | End | E-Value | Type |
|---|
|
CG-1
|
34 |
150 |
8.08e-88 |
SMART |
|
low complexity region
|
227 |
238 |
N/A |
INTRINSIC |
|
low complexity region
|
268 |
286 |
N/A |
INTRINSIC |
|
low complexity region
|
289 |
300 |
N/A |
INTRINSIC |
|
low complexity region
|
309 |
324 |
N/A |
INTRINSIC |
|
low complexity region
|
365 |
375 |
N/A |
INTRINSIC |
|
low complexity region
|
412 |
430 |
N/A |
INTRINSIC |
|
low complexity region
|
456 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
496 |
509 |
N/A |
INTRINSIC |
|
Pfam:TIG
|
536 |
616 |
1.2e-8 |
PFAM |
|
low complexity region
|
655 |
674 |
N/A |
INTRINSIC |
|
Blast:ANK
|
712 |
745 |
7e-12 |
BLAST |
|
SCOP:d1myo__
|
713 |
811 |
2e-15 |
SMART |
|
Blast:ANK
|
757 |
787 |
4e-11 |
BLAST |
|
low complexity region
|
824 |
834 |
N/A |
INTRINSIC |
|
low complexity region
|
839 |
848 |
N/A |
INTRINSIC |
|
low complexity region
|
856 |
877 |
N/A |
INTRINSIC |
|
IQ
|
1048 |
1070 |
2.59e2 |
SMART |
|
IQ
|
1071 |
1087 |
2.38e2 |
SMART |
|
IQ
|
1101 |
1123 |
5.42e0 |
SMART |
|
low complexity region
|
1135 |
1152 |
N/A |
INTRINSIC |
|
low complexity region
|
1175 |
1185 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108545
AA Change: I649T
PolyPhen 2
Score 0.038 (Sensitivity: 0.94; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000104185
Gene: ENSMUSG00000040712
AA Change: I649T
| Domain | Start | End | E-Value | Type |
|---|
|
CG-1
|
34 |
126 |
3.23e-55 |
SMART |
|
low complexity region
|
203 |
214 |
N/A |
INTRINSIC |
|
low complexity region
|
244 |
262 |
N/A |
INTRINSIC |
|
low complexity region
|
265 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
285 |
300 |
N/A |
INTRINSIC |
|
low complexity region
|
341 |
351 |
N/A |
INTRINSIC |
|
low complexity region
|
388 |
406 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
456 |
N/A |
INTRINSIC |
|
low complexity region
|
472 |
485 |
N/A |
INTRINSIC |
|
Pfam:TIG
|
512 |
592 |
1.1e-8 |
PFAM |
|
low complexity region
|
631 |
650 |
N/A |
INTRINSIC |
|
Blast:ANK
|
688 |
721 |
7e-12 |
BLAST |
|
SCOP:d1myo__
|
689 |
787 |
2e-15 |
SMART |
|
Blast:ANK
|
733 |
763 |
5e-13 |
BLAST |
|
low complexity region
|
800 |
810 |
N/A |
INTRINSIC |
|
low complexity region
|
815 |
824 |
N/A |
INTRINSIC |
|
low complexity region
|
832 |
853 |
N/A |
INTRINSIC |
|
IQ
|
1024 |
1046 |
2.59e2 |
SMART |
|
IQ
|
1047 |
1069 |
1.18e1 |
SMART |
|
IQ
|
1070 |
1092 |
5.42e0 |
SMART |
|
low complexity region
|
1104 |
1121 |
N/A |
INTRINSIC |
|
low complexity region
|
1144 |
1154 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000119120
AA Change: I673T
PolyPhen 2
Score 0.112 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000113847
Gene: ENSMUSG00000040712
AA Change: I673T
| Domain | Start | End | E-Value | Type |
|---|
|
CG-1
|
34 |
150 |
8.08e-88 |
SMART |
|
low complexity region
|
227 |
238 |
N/A |
INTRINSIC |
|
low complexity region
|
268 |
286 |
N/A |
INTRINSIC |
|
low complexity region
|
289 |
300 |
N/A |
INTRINSIC |
|
low complexity region
|
309 |
324 |
N/A |
INTRINSIC |
|
low complexity region
|
365 |
375 |
N/A |
INTRINSIC |
|
low complexity region
|
412 |
430 |
N/A |
INTRINSIC |
|
low complexity region
|
456 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
496 |
509 |
N/A |
INTRINSIC |
|
Pfam:TIG
|
536 |
616 |
1.1e-8 |
PFAM |
|
low complexity region
|
655 |
674 |
N/A |
INTRINSIC |
|
Blast:ANK
|
712 |
745 |
7e-12 |
BLAST |
|
SCOP:d1myo__
|
713 |
811 |
2e-15 |
SMART |
|
Blast:ANK
|
757 |
787 |
8e-13 |
BLAST |
|
low complexity region
|
824 |
834 |
N/A |
INTRINSIC |
|
low complexity region
|
839 |
848 |
N/A |
INTRINSIC |
|
low complexity region
|
856 |
877 |
N/A |
INTRINSIC |
|
IQ
|
1048 |
1070 |
2.59e2 |
SMART |
|
IQ
|
1071 |
1093 |
1.18e1 |
SMART |
|
IQ
|
1094 |
1116 |
5.42e0 |
SMART |
|
low complexity region
|
1128 |
1145 |
N/A |
INTRINSIC |
|
low complexity region
|
1168 |
1178 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000120261
AA Change: I649T
PolyPhen 2
Score 0.023 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000113667
Gene: ENSMUSG00000040712
AA Change: I649T
| Domain | Start | End | E-Value | Type |
|---|
|
CG-1
|
34 |
126 |
3.23e-55 |
SMART |
|
low complexity region
|
203 |
214 |
N/A |
INTRINSIC |
|
low complexity region
|
244 |
262 |
N/A |
INTRINSIC |
|
low complexity region
|
265 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
285 |
300 |
N/A |
INTRINSIC |
|
low complexity region
|
341 |
351 |
N/A |
INTRINSIC |
|
low complexity region
|
388 |
406 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
456 |
N/A |
INTRINSIC |
|
low complexity region
|
472 |
485 |
N/A |
INTRINSIC |
|
Pfam:TIG
|
512 |
592 |
1e-8 |
PFAM |
|
low complexity region
|
631 |
650 |
N/A |
INTRINSIC |
|
Blast:ANK
|
688 |
721 |
7e-12 |
BLAST |
|
SCOP:d1myo__
|
689 |
787 |
2e-15 |
SMART |
|
Blast:ANK
|
733 |
763 |
7e-13 |
BLAST |
|
low complexity region
|
800 |
810 |
N/A |
INTRINSIC |
|
low complexity region
|
815 |
824 |
N/A |
INTRINSIC |
|
low complexity region
|
832 |
853 |
N/A |
INTRINSIC |
|
IQ
|
1024 |
1046 |
2.59e2 |
SMART |
|
IQ
|
1047 |
1063 |
2.38e2 |
SMART |
|
IQ
|
1077 |
1099 |
5.42e0 |
SMART |
|
low complexity region
|
1111 |
1128 |
N/A |
INTRINSIC |
|
low complexity region
|
1151 |
1161 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000125687
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000145823
|
| SMART Domains |
Protein: ENSMUSP00000123602
Gene: ENSMUSG00000040712
| Domain | Start | End | E-Value | Type |
|---|
|
CG-1
|
34 |
137 |
2.55e-44 |
SMART |
|
low complexity region
|
146 |
165 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 98.7%
- 3x: 97.5%
- 10x: 93.3%
- 20x: 82.6%
|
| Validation Efficiency |
96% (67/70) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the calmodulin-binding transcription activator protein family. Members of this family share a common domain structure that consists of a transcription activation domain, a DNA-binding domain, and a calmodulin-binding domain. The encoded protein may be a transcriptional coactivator of genes involved in cardiac growth. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jan 2010]
PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and free of obvious cardiac defects, but show reduced pathophysiologic cardiac hypertrophy in response to diverse stress stimuli. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 56 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadacl4fm2 |
T |
A |
4: 144,291,635 (GRCm39) |
I24L |
probably benign |
Het |
| Ano1 |
A |
G |
7: 144,187,426 (GRCm39) |
W447R |
possibly damaging |
Het |
| Blm |
T |
A |
7: 80,105,165 (GRCm39) |
K103* |
probably null |
Het |
| Catsperz |
G |
A |
19: 6,902,450 (GRCm39) |
R15C |
probably damaging |
Het |
| Chd1l |
T |
C |
3: 97,510,964 (GRCm39) |
|
probably benign |
Het |
| Corin |
C |
A |
5: 72,462,276 (GRCm39) |
E844D |
possibly damaging |
Het |
| Cyb5rl |
T |
G |
4: 106,938,104 (GRCm39) |
M127R |
probably damaging |
Het |
| Dcdc2a |
A |
T |
13: 25,286,569 (GRCm39) |
N164I |
possibly damaging |
Het |
| Dnah6 |
A |
G |
6: 73,185,528 (GRCm39) |
|
probably null |
Het |
| Emilin2 |
T |
C |
17: 71,562,960 (GRCm39) |
|
probably benign |
Het |
| Epb41l2 |
T |
A |
10: 25,319,800 (GRCm39) |
V211D |
probably damaging |
Het |
| Fbxo47 |
C |
T |
11: 97,759,427 (GRCm39) |
M166I |
probably benign |
Het |
| Golm1 |
T |
C |
13: 59,786,187 (GRCm39) |
D335G |
probably damaging |
Het |
| Gpn1 |
T |
A |
5: 31,660,773 (GRCm39) |
M188K |
probably damaging |
Het |
| Gpr84 |
T |
A |
15: 103,217,646 (GRCm39) |
S144C |
probably damaging |
Het |
| Grm8 |
G |
T |
6: 27,981,200 (GRCm39) |
Q237K |
possibly damaging |
Het |
| Gsdmd |
C |
A |
15: 75,738,908 (GRCm39) |
|
probably null |
Het |
| Hmgcr |
G |
A |
13: 96,795,528 (GRCm39) |
T347I |
probably damaging |
Het |
| Hsd17b7 |
T |
A |
1: 169,788,774 (GRCm39) |
|
probably benign |
Het |
| Hsd3b9 |
G |
A |
3: 98,354,182 (GRCm39) |
Q106* |
probably null |
Het |
| Klhl7 |
T |
G |
5: 24,364,489 (GRCm39) |
W508G |
probably damaging |
Het |
| Lrp2 |
C |
A |
2: 69,258,948 (GRCm39) |
D4581Y |
probably damaging |
Het |
| Lrrc7 |
T |
C |
3: 157,840,968 (GRCm39) |
N1357D |
probably benign |
Het |
| Macf1 |
T |
C |
4: 123,380,451 (GRCm39) |
|
probably benign |
Het |
| Mroh7 |
T |
C |
4: 106,577,692 (GRCm39) |
T329A |
probably damaging |
Het |
| Mroh9 |
C |
T |
1: 162,871,552 (GRCm39) |
|
probably null |
Het |
| Mta2 |
A |
G |
19: 8,926,550 (GRCm39) |
|
probably benign |
Het |
| Myo3a |
A |
T |
2: 22,271,906 (GRCm39) |
|
probably benign |
Het |
| Nrip2 |
A |
G |
6: 128,384,352 (GRCm39) |
D153G |
probably benign |
Het |
| Nup133 |
T |
C |
8: 124,644,156 (GRCm39) |
|
probably benign |
Het |
| Nup210 |
C |
T |
6: 91,019,329 (GRCm39) |
V259M |
possibly damaging |
Het |
| Or10ak14 |
C |
T |
4: 118,610,816 (GRCm39) |
M308I |
probably benign |
Het |
| Or5b112 |
A |
T |
19: 13,319,211 (GRCm39) |
I30F |
probably benign |
Het |
| Or9i14 |
A |
T |
19: 13,792,726 (GRCm39) |
V76D |
probably damaging |
Het |
| Otog |
C |
T |
7: 45,939,113 (GRCm39) |
R2048C |
probably damaging |
Het |
| Pacc1 |
T |
C |
1: 191,080,632 (GRCm39) |
V284A |
probably damaging |
Het |
| Paqr7 |
T |
C |
4: 134,235,124 (GRCm39) |
L327P |
probably damaging |
Het |
| Parl |
A |
G |
16: 20,105,676 (GRCm39) |
S249P |
probably damaging |
Het |
| Phc1 |
A |
G |
6: 122,302,833 (GRCm39) |
I230T |
probably benign |
Het |
| Pitpnm1 |
T |
G |
19: 4,160,831 (GRCm39) |
|
probably null |
Het |
| Plpp1 |
A |
G |
13: 112,971,477 (GRCm39) |
Y48C |
probably damaging |
Het |
| Pxdc1 |
A |
G |
13: 34,812,870 (GRCm39) |
F194L |
probably benign |
Het |
| Rp1 |
A |
T |
1: 4,416,159 (GRCm39) |
V1651D |
possibly damaging |
Het |
| Serpinb1c |
T |
A |
13: 33,080,943 (GRCm39) |
R47* |
probably null |
Het |
| Sis |
T |
C |
3: 72,853,915 (GRCm39) |
T521A |
possibly damaging |
Het |
| Slc16a9 |
A |
G |
10: 70,118,308 (GRCm39) |
D209G |
probably benign |
Het |
| Slc26a4 |
A |
T |
12: 31,575,567 (GRCm39) |
C706* |
probably null |
Het |
| Slc37a2 |
A |
G |
9: 37,148,177 (GRCm39) |
V325A |
probably benign |
Het |
| Speg |
T |
A |
1: 75,378,145 (GRCm39) |
D784E |
probably damaging |
Het |
| Sycp1 |
T |
C |
3: 102,827,938 (GRCm39) |
I270V |
probably benign |
Het |
| Tatdn2 |
T |
A |
6: 113,681,076 (GRCm39) |
F309I |
probably damaging |
Het |
| Tmem67 |
T |
C |
4: 12,089,400 (GRCm39) |
|
probably benign |
Het |
| Trpm1 |
T |
A |
7: 63,852,801 (GRCm39) |
|
probably null |
Het |
| Wrn |
T |
C |
8: 33,782,714 (GRCm39) |
R496G |
probably damaging |
Het |
| Zfhx2 |
A |
G |
14: 55,300,854 (GRCm39) |
V2299A |
probably benign |
Het |
| Zfp819 |
T |
A |
7: 43,266,524 (GRCm39) |
S260T |
possibly damaging |
Het |
|
| Other mutations in Camta2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01022:Camta2
|
APN |
11 |
70,562,308 (GRCm39) |
nonsense |
probably null |
|
|
IGL01472:Camta2
|
APN |
11 |
70,574,950 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02548:Camta2
|
APN |
11 |
70,561,511 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02794:Camta2
|
APN |
11 |
70,566,484 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02983:Camta2
|
APN |
11 |
70,562,848 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03035:Camta2
|
APN |
11 |
70,562,335 (GRCm39) |
nonsense |
probably null |
|
|
weeping
|
UTSW |
11 |
70,574,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Willow
|
UTSW |
11 |
70,569,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
P0027:Camta2
|
UTSW |
11 |
70,574,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0360:Camta2
|
UTSW |
11 |
70,574,136 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0364:Camta2
|
UTSW |
11 |
70,574,136 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0541:Camta2
|
UTSW |
11 |
70,572,447 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0600:Camta2
|
UTSW |
11 |
70,564,785 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0630:Camta2
|
UTSW |
11 |
70,569,131 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1346:Camta2
|
UTSW |
11 |
70,567,293 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1826:Camta2
|
UTSW |
11 |
70,574,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1881:Camta2
|
UTSW |
11 |
70,562,842 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1980:Camta2
|
UTSW |
11 |
70,573,308 (GRCm39) |
missense |
probably benign |
0.43 |
|
R2144:Camta2
|
UTSW |
11 |
70,562,401 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2145:Camta2
|
UTSW |
11 |
70,562,401 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2763:Camta2
|
UTSW |
11 |
70,573,356 (GRCm39) |
nonsense |
probably null |
|
|
R2881:Camta2
|
UTSW |
11 |
70,570,490 (GRCm39) |
splice site |
probably null |
|
|
R2917:Camta2
|
UTSW |
11 |
70,571,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4115:Camta2
|
UTSW |
11 |
70,567,300 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4321:Camta2
|
UTSW |
11 |
70,569,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4470:Camta2
|
UTSW |
11 |
70,571,766 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4499:Camta2
|
UTSW |
11 |
70,565,512 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4509:Camta2
|
UTSW |
11 |
70,571,844 (GRCm39) |
missense |
probably benign |
0.28 |
|
R6154:Camta2
|
UTSW |
11 |
70,569,211 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6166:Camta2
|
UTSW |
11 |
70,565,087 (GRCm39) |
splice site |
probably null |
|
|
R6287:Camta2
|
UTSW |
11 |
70,572,295 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6382:Camta2
|
UTSW |
11 |
70,562,867 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6864:Camta2
|
UTSW |
11 |
70,562,792 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6922:Camta2
|
UTSW |
11 |
70,564,964 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7438:Camta2
|
UTSW |
11 |
70,574,714 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7611:Camta2
|
UTSW |
11 |
70,572,372 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7883:Camta2
|
UTSW |
11 |
70,566,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8094:Camta2
|
UTSW |
11 |
70,576,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8232:Camta2
|
UTSW |
11 |
70,573,841 (GRCm39) |
missense |
unknown |
|
|
R8271:Camta2
|
UTSW |
11 |
70,561,886 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8973:Camta2
|
UTSW |
11 |
70,561,184 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9072:Camta2
|
UTSW |
11 |
70,567,234 (GRCm39) |
missense |
probably benign |
0.21 |
|
T0722:Camta2
|
UTSW |
11 |
70,574,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0066:Camta2
|
UTSW |
11 |
70,572,504 (GRCm39) |
missense |
probably benign |
0.08 |
|
Z1177:Camta2
|
UTSW |
11 |
70,566,047 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AAATAGTCCCAAGCCTGTCATGCC -3'
(R):5'- GCGTAGAGGAAGAACAAGCTCCATC -3'
Sequencing Primer
(F):5'- AAGCCTGTCATGCCACGAG -3'
(R):5'- GAGTACAACTCCTAGTAGTGTTCC -3'
|
| Posted On |
2014-02-18 |
Incidental Mutation